Detalhe da pesquisa
1.
Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase.
Immunity
; 31(4): 587-97, 2009 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19818650
2.
Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors.
Proc Natl Acad Sci U S A
; 112(32): E4410-7, 2015 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26216984
3.
IL-2-inducible T-cell kinase modulates TH2-mediated allergic airway inflammation by suppressing IFN-γ in naive CD4+ T cells.
J Allergy Clin Immunol
; 132(4): 811-20.e1-5, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23768572
4.
Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses.
J Immunol
; 181(9): 6125-31, 2008 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18941202
5.
Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma.
Mol Cancer Ther
; 16(9): 1729-1738, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28619758
6.
Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs.
Nat Commun
; 7: 12351, 2016 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27484502
7.
Proline Starvation Induces Unresolved ER Stress and Hinders mTORC1-Dependent Tumorigenesis.
Cell Metab
; 24(5): 753-761, 2016 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27618686
8.
Modeling susceptibility versus resistance in allergic airway disease reveals regulation by Tec kinase Itk.
PLoS One
; 5(6): e11348, 2010 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20596543
9.
ITK inhibitors in inflammation and immune-mediated disorders.
Curr Top Med Chem
; 9(8): 690-703, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19689375
10.
Differential sensitivity to Itk kinase signals for T helper 2 cytokine production and chemokine-mediated migration.
J Immunol
; 180(6): 3833-8, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18322190
11.
Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma.
J Exp Med
; 205(6): 1285-92, 2008 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18490489
12.
Memory phenotype CD8+ T cells with innate function selectively develop in the absence of active Itk.
Eur J Immunol
; 37(10): 2892-9, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17724684
13.
Differential regulation of cytokine production by CD1d-restricted NKT cells in response to superantigen staphylococcal enterotoxin B exposure.
Infect Immun
; 74(1): 282-8, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16368982
14.
Tec kinase Itk forms membrane clusters specifically in the vicinity of recruiting receptors.
J Biol Chem
; 281(50): 38529-34, 2006 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17060314
15.
Reduced airway hyperresponsiveness and tracheal responses during allergic asthma in mice lacking tyrosine kinase inducible T-cell kinase.
J Allergy Clin Immunol
; 117(4): 780-6, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16630934