Detalhe da pesquisa
1.
Management of pharmaceutical ICH M7 (Q)SAR predictions - The impact of model updates.
Regul Toxicol Pharmacol
; 118: 104807, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33058939
2.
Computing similarity between structural environments of mutagenicity alerts.
Mutagenesis
; 34(1): 55-65, 2019 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30346583
3.
Improvement of quantitative structure-activity relationship (QSAR) tools for predicting Ames mutagenicity: outcomes of the Ames/QSAR International Challenge Project.
Mutagenesis
; 34(1): 3-16, 2019 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30357358
4.
Transitioning to composite bacterial mutagenicity models in ICH M7 (Q)SAR analyses.
Regul Toxicol Pharmacol
; 109: 104488, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586682
5.
Critical evaluation of human oral bioavailability for pharmaceutical drugs by using various cheminformatics approaches.
Pharm Res
; 31(4): 1002-14, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24306326
6.
Optimizing predictive performance of CASE Ultra expert system models using the applicability domains of individual toxicity alerts.
J Chem Inf Model
; 52(10): 2609-18, 2012 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22947043
7.
MultiCASE Platform for In Silico Toxicology.
Methods Mol Biol
; 2425: 497-518, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35188644
8.
Benchmark performance of MultiCASE Inc. software in Ames mutagenicity set.
J Chem Inf Model
; 50(9): 1521, 2010 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20695480
9.
MultiCASE Expert Systems and the REACH Initiative.
Toxicol Mech Methods
; 18(2-3): 159-75, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-20020912
10.
ADME evaluation. 2. A computer model for the prediction of intestinal absorption in humans.
Eur J Pharm Sci
; 17(4-5): 253-63, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12453615
11.
Effectiveness of CASE Ultra Expert System in Evaluating Adverse Effects of Drugs.
Mol Inform
; 32(1): 87-97, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27481026
12.
ESP: a method to predict toxicity and pharmacological properties of chemicals using multiple MCASE databases.
J Chem Inf Comput Sci
; 44(2): 704-15, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15032553