Detalhe da pesquisa
1.
Design, synthesis and antiviral evaluation of novel conjugates of the 1,7,7-trimethylbicyclo[2.2.1]heptane scaffold and saturated N-heterocycles via 1,2,3-triazole linker.
Arch Pharm (Weinheim)
; 357(3): e2300549, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38036303
2.
Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives.
Int J Mol Sci
; 25(2)2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38279210
3.
New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling.
Molecules
; 29(3)2024 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38338326
4.
Terpene-Containing Analogues of Glitazars as Potential Therapeutic Agents for Metabolic Syndrome.
Curr Issues Mol Biol
; 45(3): 2230-2247, 2023 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36975514
5.
On Associations between Fear-Induced Aggression, Bdnf Transcripts, and Serotonin Receptors in the Brains of Norway Rats: An Influence of Antiaggressive Drug TC-2153.
Int J Mol Sci
; 24(2)2023 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36674499
6.
Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1.
Int J Mol Sci
; 24(6)2023 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982848
7.
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties.
Int J Mol Sci
; 24(4)2023 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36835244
8.
Synthesis and Evaluation of Hypoglycemic Activity of Structural Isomers of ((Benzyloxy)phenyl)propanoic Acid Bearing an Aminobornyl Moiety.
Int J Mol Sci
; 24(9)2023 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175725
9.
Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor.
Int J Mol Sci
; 24(6)2023 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982223
10.
New 5-Hydroxycoumarin-Based Tyrosyl-DNA Phosphodiesterase I Inhibitors Sensitize Tumor Cell Line to Topotecan.
Int J Mol Sci
; 24(11)2023 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298106
11.
Identification and Study of the Action Mechanism of Small Compound That Inhibits Replication of Respiratory Syncytial Virus.
Int J Mol Sci
; 24(16)2023 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37629115
12.
A New Stereoselective Approach to the Substitution of Allyl Hydroxy Group in para-Mentha-1,2-diol in the Search for New Antiparkinsonian Agents.
Molecules
; 28(21)2023 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37959723
13.
New Inhibitors of Respiratory Syncytial Virus (RSV) Replication Based on Monoterpene-Substituted Arylcoumarins.
Molecules
; 28(6)2023 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36985645
14.
Novel O-acylated amidoximes and substituted 1,2,4-oxadiazoles synthesised from (+)-ketopinic acid possessing potent virus-inhibiting activity against phylogenetically distinct influenza A viruses.
Bioorg Med Chem Lett
; 55: 128465, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34808389
15.
Monoterpene substituted thiazolidin-4-ones as novel TDP1 inhibitors: Synthesis, biological evaluation and docking.
Bioorg Med Chem Lett
; 73: 128909, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35907608
16.
Study of Hypoglycemic Activity of Novel 9-N-alkyltetrahydroberberine Derivatives.
Int J Mol Sci
; 23(22)2022 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430664
17.
Novel Epoxides of Soloxolone Methyl: An Effect of the Formation of Oxirane Ring and Stereoisomerism on Cytotoxic Profile, Anti-Metastatic and Anti-Inflammatory Activities In Vitro and In Vivo.
Int J Mol Sci
; 23(11)2022 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35682893
18.
Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles.
Molecules
; 27(15)2022 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35897931
19.
Triterpenic Acid Amides as Potential Inhibitors of the SARS-CoV-2 Main Protease.
Molecules
; 28(1)2022 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36615498
20.
A Newly Identified Monoterpenoid-Based Small Molecule Able to Support the Survival of Primary Cultured Dopamine Neurons and Alleviate MPTP-Induced Toxicity In Vivo.
Molecules
; 27(23)2022 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36500381