Detalhe da pesquisa
1.
TCR-induced alteration of primary MHC peptide anchor residue.
Eur J Immunol
; 49(7): 1052-1066, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31091334
2.
Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases.
Chemistry
; 23(52): 12815-12824, 2017 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28703303
3.
T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions.
J Biol Chem
; 289(2): 628-38, 2014 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24196962
4.
T-cell receptor specificity maintained by altered thermodynamics.
J Biol Chem
; 288(26): 18766-75, 2013 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23698002
5.
Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors.
Cancer Immunol Immunother
; 62(4): 773-85, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23263452
6.
Structural and kinetic basis for heightened immunogenicity of T cell vaccines.
J Exp Med
; 201(8): 1243-55, 2005 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15837811
7.
Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA.
J Clin Invest
; 130(5): 2673-2688, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32310221
8.
T cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding.
Mol Immunol
; 45(9): 2700-9, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18243322
9.
Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor.
Proteins
; 67(1): 65-74, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17243170
10.
Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry.
Protein Eng Des Sel
; 20(8): 397-403, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17644531
11.
Crystallization and preliminary X-ray structural studies of a Melan-A pMHC-TCR complex.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 63(Pt 9): 758-60, 2007 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17768347
12.
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci
; 15(4): 710-21, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16600963
13.
Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep
; 6: 18851, 2016 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26758806
14.
Crystallization and preliminary X-ray structural studies of a high-affinity CD8alphaalpha co-receptor to pMHC.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 61(Pt 3): 285-7, 2005 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16511019
15.
Increased Peptide Contacts Govern High Affinity Binding of a Modified TCR Whilst Maintaining a Native pMHC Docking Mode.
Front Immunol
; 4: 168, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23805144
16.
Monoclonal TCR-redirected tumor cell killing.
Nat Med
; 18(6): 980-7, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22561687
17.
High affinity soluble ILT2 receptor: a potent inhibitor of CD8(+) T cell activation.
Protein Cell
; 1(12): 1118-27, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21213105
18.
Human TCR-binding affinity is governed by MHC class restriction.
J Immunol
; 178(9): 5727-34, 2007 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17442956
19.
Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur J Immunol
; 36(1): 170-9, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16323248
20.
Stable, soluble T-cell receptor molecules for crystallization and therapeutics.
Protein Eng
; 16(9): 707-11, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-14560057