Detalhe da pesquisa
1.
Rivaroxaban, a direct Factor Xa inhibitor, versus acetylsalicylic acid as thromboprophylaxis in children post-Fontan procedure: Rationale and design of a prospective, randomized trial (the UNIVERSE study).
Am Heart J
; 213: 97-104, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31132584
2.
Pharmacokinetic-Pharmacodynamic Characterization of Relapse Risk for Paliperidone Palmitate 1-Month and 3-Month Formulations.
J Clin Psychopharmacol
; 39(6): 567-574, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31688450
3.
Prospective dose selection and acceleration of paliperidone palmitate 3-month formulation development using a pharmacometric bridging strategy.
Br J Clin Pharmacol
; 82(5): 1364-1370, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27333588
4.
Model-Informed Clinical Development of Once-Every-6-Month Injection of Paliperidone Palmitate in Patients with Schizophrenia: A Pharmacometric Bridging Approach (Part I).
Eur J Drug Metab Pharmacokinet
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38750386
5.
Considerations for Industry-Preparing for the FDA Model-Informed Drug Development (MIDD) Paired Meeting Program.
Clin Pharmacol Ther
; 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38519861
6.
Disease progression model in subjects with mild cognitive impairment from the Alzheimer's disease neuroimaging initiative: CSF biomarkers predict population subtypes.
Br J Clin Pharmacol
; 75(1): 146-61, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22534009
7.
Mixed-effects beta regression for modeling continuous bounded outcome scores using NONMEM when data are not on the boundaries.
J Pharmacokinet Pharmacodyn
; 40(4): 537-44, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23645382
8.
The ADAS-Cog revisited: novel composite scales based on ADAS-Cog to improve efficiency in MCI and early AD trials.
Alzheimers Dement
; 9(1 Suppl): S21-31, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23127469
9.
Population Pharmacokinetics and Exposure-Response with Teclistamab in Patients With Relapsed/Refractory Multiple Myeloma: Results From MajesTEC-1.
Target Oncol
; 18(5): 667-684, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37713090
10.
A one-year prospective study of the safety, tolerability and pharmacokinetics of the highest available dose of paliperidone palmitate in patients with schizophrenia.
BMC Psychiatry
; 12: 26, 2012 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22455454
11.
Efficacy and safety of glucagon-like peptide-1/glucagon receptor co-agonist JNJ-64565111 in individuals with obesity without type 2 diabetes mellitus: A randomized dose-ranging study.
Clin Obes
; 11(2): e12432, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33475255
12.
Efficacy and safety of glucagon-like peptide-1/glucagon receptor co-agonist JNJ-64565111 in individuals with type 2 diabetes mellitus and obesity: A randomized dose-ranging study.
Clin Obes
; 11(2): e12433, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33475251
13.
Population pharmacokinetics of doripenem based on data from phase 1 studies with healthy volunteers and phase 2 and 3 studies with critically ill patients.
Antimicrob Agents Chemother
; 54(6): 2354-9, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385854
14.
Pharmacokinetic-pharmacodynamic-model-guided doripenem dosing in critically ill patients.
Antimicrob Agents Chemother
; 54(6): 2360-4, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385857
15.
Simple pharmacometric tools for oral anti-diabetic drug development: competitive landscape for oral non-insulin therapies in type 2 diabetes.
Biopharm Drug Dispos
; 31(2-3): 162-77, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20213855
16.
Population Pharmacokinetics of Paliperidone Palmitate (Once-Monthly Formulation) in Japanese, Korean, and Taiwanese Patients With Schizophrenia.
Clin Pharmacol Drug Dev
; 9(2): 224-234, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31876117
17.
Pharmacodynamic profiling of ceftobiprole for treatment of complicated skin and skin structure infections.
Antimicrob Agents Chemother
; 53(8): 3371-4, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19528285
18.
Pharmacokinetic and pharmacodynamic modeling of pegylated thrombopoietin mimetic peptide (PEG-TPOm) after single intravenous dose administration in healthy subjects.
J Clin Pharmacol
; 49(3): 336-50, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19246731
19.
Dosing and Switching Strategies for Paliperidone Palmitate 3-Month Formulation in Patients with Schizophrenia Based on Population Pharmacokinetic Modeling and Simulation, and Clinical Trial Data.
CNS Drugs
; 31(4): 273-288, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28258365
20.
Population Pharmacokinetics of a Novel Once-Every 3 Months Intramuscular Formulation of Paliperidone Palmitate in Patients with Schizophrenia.
Clin Pharmacokinet
; 56(4): 421-433, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27743205