Detalhe da pesquisa
1.
Mechanistic incorporation of FcRn binding in plasma and endosomes in a whole body PBPK model for large molecules.
J Pharmacokinet Pharmacodyn
; 50(3): 229-241, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36877385
2.
Pharmacokinetics, Safety, and Tolerability of Brivaracetam in Healthy Elderly Participants.
Clin Pharmacol Drug Dev
; 12(11): 1121-1127, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37212183
3.
Caplacizumab Model-Based Dosing Recommendations in Pediatric Patients With Acquired Thrombotic Thrombocytopenic Purpura.
J Clin Pharmacol
; 62(3): 409-421, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699078
4.
Physiologically based pharmacokinetics (PBPK).
Drug Metab Rev
; 41(3): 391-407, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19601719
5.
Population pharmacokinetic and pharmacodynamic analysis in allergic diseases.
Drug Metab Rev
; 41(3): 475-85, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19601723
6.
From pharmacokinetics to therapeutics.
Drug Metab Rev
; 41(3): 455-74, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19601722
7.
Clinical pharmacology of caplacizumab for the treatment of patients with acquired thrombotic thrombocytopenic purpura.
Expert Rev Clin Pharmacol
; 12(6): 537-545, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30977686
8.
Retrospective population pharmacokinetic analysis of levetiracetam in children and adolescents with epilepsy: dosing recommendations.
Clin Pharmacokinet
; 47(5): 333-41, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18399714
9.
Pharmacokinetics and metabolism of 14C-brivaracetam, a novel SV2A ligand, in healthy subjects.
Drug Metab Dispos
; 36(1): 36-45, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17908923
10.
The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after multiple increasing oral doses in healthy men.
Br J Clin Pharmacol
; 66(1): 71-5, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18341673
11.
Population pharmacokinetics of levetiracetam in Japanese and Western adults.
Clin Pharmacokinet
; 46(6): 503-12, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17518509
12.
Modeling and simulation of intravenous levetiracetam pharmacokinetic profiles in children to evaluate dose adaptation rules.
Epilepsy Res
; 76(2-3): 140-7, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17851036
13.
Brivaracetam disposition in mild to severe hepatic impairment.
J Clin Pharmacol
; 53(6): 633-41, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23649964
14.
Brivaracetam disposition in renal impairment.
J Clin Pharmacol
; 52(12): 1927-33, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22235139
15.
Assessment of levetiracetam bioavailability from targeted sites in the human intestine using remotely activated capsules and gamma scintigraphy: Open-label, single-dose, randomized, four-way crossover study in healthy male volunteers.
Clin Ther
; 32(10): 1813-21, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21194605
16.
Pharmacokinetics of levetiracetam XR 500mg tablets.
Epilepsy Res
; 84(2-3): 224-31, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19264451
17.
The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after single increasing oral doses in healthy males.
Br J Clin Pharmacol
; 63(6): 680-8, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17223857