Detalhe da pesquisa
1.
Design, Synthesis of Biaryl Piperidine Derivatives and Their Evaluation as Potential Antileishmanial Agents against Leishmania donovani Strain Ag83.
Chem Biodivers
; 18(7): e2100105, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34036717
2.
Macrocyclic hexaoxazoles: Influence of aminoalkyl substituents on RNA and DNA G-quadruplex stabilization and cytotoxicity.
Bioorg Med Chem Lett
; 20(10): 3150-4, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20409709
3.
12-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridines as novel topoisomerase I-targeting antitumor agents.
Bioorg Med Chem
; 17(7): 2877-85, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19303306
4.
A review on HCV inhibitors: Significance of non-structural polyproteins.
Eur J Med Chem
; 164: 576-601, 2019 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639895
5.
Ring-closing metathesis for the synthesis of a highly G-quadruplex selective macrocyclic hexaoxazole having enhanced cytotoxic potency.
Bioorg Med Chem Lett
; 18(13): 3802-4, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18515097
6.
Facile formation of hydrophilic derivatives of 5H-8,9-dimethoxy-5-[2-(N,N-dimethylamino)ethyl]-2,3-methylenedioxydibenzo[c,h] [1,6]naphthyridin-6-one (ARC-111) and its 12-aza analog via quaternary ammonium intermediates.
Bioorg Med Chem Lett
; 18(12): 3570-2, 2008 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18511275
7.
11-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridine derivatives as novel topoisomerase I-targeting agents.
Bioorg Med Chem
; 16(18): 8598-606, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18771930
8.
Syntheses and biological evaluation of topoisomerase I-targeting agents related to 11-[2-(N,N-dimethylamino)ethyl]-2,3-dimethoxy-8,9-methylenedioxy-11H-isoquino[4,3-c]cinnolin-12-one (ARC-31).
Bioorg Med Chem
; 16(16): 7824-31, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18676151
9.
Synthesis of N-substituted 5-[2-(N-alkylamino)ethyl]dibenzo[c,h][1,6]naphthyridines as novel topoisomerase I-targeting antitumor agents.
Bioorg Med Chem
; 16(20): 9295-301, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18829334
10.
Flavone-based novel antidiabetic and antidyslipidemic agents.
J Med Chem
; 55(10): 4551-67, 2012 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22524508
11.
Novel topoisomerase I-targeting antitumor agents synthesized from the N,N,N-trimethylammonium derivative of ARC-111, 5H-2,3-dimethoxy-8,9-methylenedioxy-5-[(2-N,N,N-trimethylammonium)ethyl]dibenzo[c,h][1,6]naphthyridin-6-one iodide.
Eur J Med Chem
; 44(9): 3433-8, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19299037