Detalhe da pesquisa
1.
FOXO3: at the crossroads of metabolic, inflammatory, and tumorigenic remodeling in the colon.
Am J Physiol Gastrointest Liver Physiol
; 326(3): G247-G251, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38193202
2.
FOXO3 Deficiency in Neutrophils Drives Colonic Inflammation and Tumorigenesis.
Int J Mol Sci
; 24(11)2023 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298680
3.
Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation.
FASEB J
; 31(5): 2013-2025, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28183804
4.
High-fat diet induced leptin and Wnt expression: RNA-sequencing and pathway analysis of mouse colonic tissue and tumors.
Carcinogenesis
; 38(3): 302-311, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28426873
5.
Intestinal inflammation requires FOXO3 and prostaglandin E2-dependent lipogenesis and elevated lipid droplets.
Am J Physiol Gastrointest Liver Physiol
; 310(10): G844-54, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26968210
6.
Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6.
Biochem Biophys Res Commun
; 469(3): 370-6, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26657850
7.
FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density.
J Biol Chem
; 288(23): 16274-16281, 2013 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23603907
8.
Comprehensive Transcriptomic Analysis of EWSR1::WT1 Targets Identifies CDK4/6 Inhibitors as an Effective Therapy for Desmoplastic Small Round Cell Tumors.
Cancer Res
; 84(9): 1426-1442, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38588409
9.
Epiploic Adipose Tissue (EPAT) in Obese Individuals Promotes Colonic Tumorigenesis: A Novel Model for EPAT-Dependent Colorectal Cancer Progression.
Cancers (Basel)
; 15(3)2023 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36765934
10.
Unraveling the Complex Interconnection between Specific Inflammatory Signaling Pathways and Mechanisms Involved in HIV-Associated Colorectal Oncogenesis.
Cancers (Basel)
; 15(3)2023 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36765706
11.
FOXO3 Expression in Macrophages Is Lowered by a High-Fat Diet and Regulates Colonic Inflammation and Tumorigenesis.
Metabolites
; 12(3)2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35323693
12.
Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells.
Am J Physiol Gastrointest Liver Physiol
; 300(2): G264-72, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21109589
13.
Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity.
BMC Cancer
; 11: 219, 2011 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21639915
14.
Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity.
Oncogenesis
; 10(11): 82, 2021 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34845203
15.
Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy.
Sci Rep
; 11(1): 9010, 2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33907256
16.
Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease.
Gut Microbes
; 11(3): 350-363, 2020 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31063017
17.
Tumor suppressor FOXO3 participates in the regulation of intestinal inflammation.
Lab Invest
; 89(9): 1053-62, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19636295
18.
Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel Targets.
Cell Mol Gastroenterol Hepatol
; 7(2): 391-408, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718226
19.
Human Adipose-Derived Hydrogel Characterization Based on In Vitro ASC Biocompatibility and Differentiation.
Stem Cells Int
; 2019: 9276398, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-32082388
20.
Tumor suppressor Foxo3a is involved in the regulation of lipopolysaccharide-induced interleukin-8 in intestinal HT-29 cells.
Infect Immun
; 76(10): 4677-85, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18678662