Detalhe da pesquisa
1.
Hypersensitivity Reactions to Obinutuzumab in Cynomolgus Monkeys and Relevance to Humans.
Toxicol Pathol
; 45(5): 676-686, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28830332
2.
First-in-Man Study With Inclacumab, a Human Monoclonal Antibody Against P-selectin.
J Cardiovasc Pharmacol
; 65(6): 611-9, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25714598
3.
Characterization of anti-drug antibody responses to the T-cell engaging bispecific antibody cibisatamab to understand the impact on exposure.
Front Immunol
; 15: 1406353, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38881900
4.
Quantifying mutant huntingtin protein in human cerebrospinal fluid to support the development of huntingtin-lowering therapies.
Sci Rep
; 13(1): 5332, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37005488
5.
Separation of fast from slow anabolism by site-specific PEGylation of insulin-like growth factor I (IGF-I).
J Biol Chem
; 286(22): 19501-10, 2011 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21460230
6.
Novel in Vivo and in Vitro Pharmacokinetic/Pharmacodynamic-Based Human Starting Dose Selection for Glofitamab.
J Pharm Sci
; 111(4): 1208-1218, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34953862
7.
Assay concept for detecting anti-drug IgM in human serum samples by using a novel recombinant human IgM positive control.
Bioanalysis
; 13(4): 253-263, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33544012
8.
PKPD Assessment of the Anti-CD20 Antibody Obinutuzumab in Cynomolgus Monkey is Feasible Despite Marked Anti-Drug Antibody Response in This Species.
J Pharm Sci
; 108(11): 3729-3736, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31351865
9.
Novel drug and soluble target tolerant antidrug antibody assay for therapeutic antibodies bearing the P329G mutation.
Bioanalysis
; 9(11): 849-859, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28517957
10.
An apparent clinical pharmacokinetic drug-drug interaction between bevacizumab and the anti-placental growth factor monoclonal antibody RO5323441 via a target-trapping mechanism.
Cancer Chemother Pharmacol
; 79(4): 661-671, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28314990
11.
Neonatal Immune Tolerance Induction to Allow Long-Term Studies With an Immunogenic Therapeutic Monoclonal Antibody in Mice.
AAPS J
; 18(2): 354-61, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26603888
12.
Validation of a ligand-binding assay for active protein drug quantification following the 'free analyte QC concept'.
Bioanalysis
; 8(24): 2537-2549, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27807984
13.
2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 3 - LBA, biomarkers and immunogenicity).
Bioanalysis
; 8(23): 2475-2496, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27855512
14.
Epitope characterization of the ADA response directed against a targeted immunocytokine.
J Pharm Biomed Anal
; 114: 296-304, 2015 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26093509
15.
An ex vivo potency assay to assess active drug levels of a GLP-1 agonistic peptide during preclinical safety studies.
Bioanalysis
; 7(24): 3063-72, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26440381
16.
Bioanalysis of therapeutic peptides: differentiating between total and anti-drug antibody bound drug using liquid chromatography-tandem mass spectrometry quantitation.
J Chromatogr A
; 1316: 69-77, 2013 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24119751
17.
Singlicate analysis in regulated bioanalysis using ligand-binding assays: where are we heading?
Bioanalysis
; 9(18): 1357-1359, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28920450
18.
Zeptosens' protein microarrays: a novel high performance microarray platform for low abundance protein analysis.
Proteomics
; 2(4): 383-93, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12164697