Detalhe da pesquisa
1.
A Single-arm Phase II Study Combining NLG207, a Nanoparticle Camptothecin, with Enzalutamide in Advanced Metastatic Castration-resistant Prostate Cancer Post-Enzalutamide.
Oncologist
; 27(9): 718-e694, 2022 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35640474
2.
Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single-Dose Administration Under Fasting Conditions in Prostate Cancer.
Oncologist
; 26(9): 729-e1493, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34333820
3.
Reviewing the role of healthy volunteer studies in drug development.
J Transl Med
; 16(1): 336, 2018 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30509294
4.
Insulin potentiation therapy for cancer?
Lancet Oncol
; 20(2): 191-192, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30712796
5.
Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders.
Geroscience
; 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38532069
6.
In Silico Re-Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure-Response Simulation.
J Clin Pharmacol
; 63(6): 672-680, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36624662
7.
A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug-Drug Interaction Liabilities.
Pharmaceutics
; 14(9)2022 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36145680
8.
Resistance to second-generation androgen receptor antagonists in prostate cancer.
Nat Rev Urol
; 18(4): 209-226, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33742189
9.
Germline Genetics of Prostate Cancer: Prevalence of Risk Variants and Clinical Implications for Disease Management.
Cancers (Basel)
; 13(9)2021 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33947030
10.
Antitumor Activity of NLG207 (Formerly CRLX101) in Combination with Enzalutamide in Preclinical Prostate Cancer Models.
Mol Cancer Ther
; 20(5): 915-924, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33632874
11.
Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies.
Sci Transl Med
; 13(578)2021 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33504652
12.
Combination treatment in metastatic castration-resistant prostate cancer: can we safely boost efficacy by adding radium-223?
Cancer Biol Ther
; 21(1): 1-3, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31530074
13.
Examining HSD3B1 as a possible biomarker to detect prostate cancer patients who are likely to progress on ADT.
Cancer Biol Ther
; 21(9): 782-784, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32791030
14.
Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors.
Cancer Chemother Pharmacol
; 86(4): 475-486, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32897402
15.
Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma.
J Pharm Biomed Anal
; 181: 113073, 2020 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31927166
16.
Phase 2 Study of Seviteronel (INO-464) in Patients With Metastatic Castration-Resistant Prostate Cancer After Enzalutamide Treatment.
Clin Genitourin Cancer
; 18(4): 258-267.e1, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32327394
17.
A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer.
Cancer Chemother Pharmacol
; 84(4): 759-770, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31367790
18.
Precision Oncology Medicine: The Clinical Relevance of Patient-Specific Biomarkers Used to Optimize Cancer Treatment.
J Clin Pharmacol
; 56(12): 1484-1499, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27197880
19.
Expanding the use of abiraterone in prostate cancer: Is earlier always better?
Cancer Biol Ther
; 19(2): 97-100, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29219670
20.
The potential role of curcumin in prostate cancer: the importance of optimizing pharmacokinetics in clinical studies.
Transl Cancer Res
; 5(Suppl 6): S1107-S1110, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30613476