Detalhe da pesquisa
1.
ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2 -/- Mice.
Mol Pharmacol
; 105(3): 194-201, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253398
2.
Optimized arylomycins are a new class of Gram-negative antibiotics.
Nature
; 561(7722): 189-194, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30209367
3.
Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening.
J Biol Chem
; 298(1): 101412, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34793835
4.
Brain-penetrant cyanoindane and cyanotetralin inhibitors of G2019S-LRRK2 kinase activity.
Bioorg Med Chem Lett
; 95: 129487, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37734423
5.
Leveraging web-based prediction calculators to set patient expectations for elective spine surgery: a qualitative study to inform implementation.
BMC Med Inform Decis Mak
; 23(1): 149, 2023 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37537577
6.
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2.
Bioorg Med Chem Lett
; 24(12): 2635-9, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24813737
7.
Combining Wearable Technology and Telehealth Counseling for Rehabilitation After Lumbar Spine Surgery: Feasibility and Acceptability of a Physical Activity Intervention.
Phys Ther
; 104(2)2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37478463
8.
Safety of early discharge after elective lumbar spine surgery with subfascial drains and association with significant reduction in length of stay.
J Neurosurg Spine
; : 1-8, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38759238
9.
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model.
J Med Chem
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38748820
10.
ent -Verticilide B1 inhibits type 2 ryanodine receptor channels and is antiarrhythmic in Casq2-/- mice.
bioRxiv
; 2023 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37461611
11.
Assessment of safety and effectiveness of non-neurosurgical management for minimal traumatic brain injury (TBI).
Injury
; 54(1): 82-86, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36028374
12.
Lipid Tales: Optimizing Arylomycin Membrane Anchors.
ACS Med Chem Lett
; 14(11): 1524-1530, 2023 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37974942
13.
RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET.
ACS Chem Biol
; 18(10): 2290-2299, 2023 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37769131
14.
Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy.
J Med Chem
; 65(19): 12895-12924, 2022 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36127295
15.
High-throughput screening in embryonic stem cell-derived neurons identifies potentiators of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate-type glutamate receptors.
J Biol Chem
; 285(22): 17209-17, 2010 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20212047
16.
Early Self-directed Home Exercise Program After Anterior Cervical Discectomy and Fusion: A Pilot Study.
Spine (Phila Pa 1976)
; 45(4): 217-225, 2020 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31490861
17.
Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory Activity.
ACS Med Chem Lett
; 11(12): 2389-2396, 2020 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33335661
18.
Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
J Med Chem
; 63(10): 5398-5420, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32302140
19.
Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity In Vitro and In Vivo.
Mol Cancer Ther
; 19(10): 1970-1980, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32788207
20.
GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.
Cell Rep
; 30(2): 381-396.e4, 2020 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31940483