Detalhe da pesquisa
1.
Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis.
Cell
; 157(6): 1279-1291, 2014 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24906147
2.
A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength.
Proc Natl Acad Sci U S A
; 109(30): 12207-12, 2012 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22761317
3.
Specificity and structure of a high affinity activin receptor-like kinase 1 (ALK1) signaling complex.
J Biol Chem
; 287(33): 27313-25, 2012 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22718755
4.
Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation.
Blood
; 117(18): 4915-23, 2011 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21393479
5.
Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis.
Arterioscler Thromb Vasc Biol
; 32(3): 613-22, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22223731
6.
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease.
Proc Natl Acad Sci U S A
; 107(11): 5124-9, 2010 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20194748
7.
Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.
J Biol Chem
; 286(34): 30034-46, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737454
8.
Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy.
Am J Pathol
; 178(3): 1287-97, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21356379
9.
Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice.
Am J Pathol
; 178(2): 784-93, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21281811
10.
Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb.
J Biol Chem
; 285(27): 21037-48, 2010 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385559
11.
Soluble activin receptor type IIB increases forward pulling tension in the mdx mouse.
Muscle Nerve
; 43(5): 694-9, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21462203
12.
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity.
Proc Natl Acad Sci U S A
; 105(19): 7082-7, 2008 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18460605
13.
Pretreatment with a soluble activin type IIB receptor/Fc fusion protein improves hypoxia-induced muscle dysfunction.
Am J Physiol Regul Integr Comp Physiol
; 298(1): R96-R103, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19864340
14.
Inhibition of the Activin Receptor Type-2B Pathway Restores Regenerative Capacity in Satellite Cell-Depleted Skeletal Muscle.
Front Physiol
; 9: 515, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29881353
15.
Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme.
Structure
; 11(6): 627-36, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12791252
16.
N-linked glycosylation of platelet P2Y12 ADP receptor is essential for signal transduction but not for ligand binding or cell surface expression.
FEBS Lett
; 562(1-3): 111-7, 2004 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-15044010
17.
Transforming growth factor-ß superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis.
Nat Med
; 20(4): 408-14, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24658078
18.
A novel therapeutic approach to treating obesity through modulation of TGFß signaling.
Endocrinology
; 153(7): 3133-46, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22549226
19.
Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.
J Exp Med
; 207(1): 85-100, 2010 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20065063
20.
A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys.
Bone
; 46(4): 1082-8, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080223