Detalhe da pesquisa
1.
α-[Amino(4-aminophenyl)thio]methylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solution.
Bioorg Chem
; 113: 104955, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34034134
2.
Synthesis of 13 C-labeled 5-aminoimidazole-4-carboxamide-1-ß-D-[13 C5 ] ribofuranosyl 5'-monophosphate.
J Labelled Comp Radiopharm
; 61(11): 820-825, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29902835
3.
Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signaling.
J Biol Chem
; 289(9): 5828-45, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24366865
4.
Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands.
Biochemistry
; 52(52): 9456-69, 2013 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-24274581
5.
Isolation of Hemiketal and Hydroxy Ketone Tautomers of Synthetic Intermediates Each Affording 18-Hydroxycortisol-1,6,7-d3.
ACS Omega
; 8(31): 28185-28195, 2023 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37576635
6.
Therapeutic potential of PIMSR, a novel CB1 receptor neutral antagonist, for cocaine use disorder: evidence from preclinical research.
Transl Psychiatry
; 12(1): 286, 2022 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35851573
7.
Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands.
Biochemistry
; 50(25): 5633-47, 2011 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21534610
8.
Designer drugs: a medicinal chemistry perspective (II).
Ann N Y Acad Sci
; 1489(1): 48-77, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32396701
9.
Selective targeting of peripheral cannabinoid receptors prevents behavioral symptoms and sensitization of trigeminal neurons in mouse models of migraine and medication overuse headache.
Pain
; 162(8): 2246-2262, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33534356
10.
Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and ß-arrestin2 with antinociceptive activity.
Mol Pharmacol
; 78(4): 560-8, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20826425
11.
Conformationally constrained analogues of N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4- dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716): design, synthesis, computational analysis, and biological evaluations.
J Med Chem
; 51(12): 3526-39, 2008 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-18512901
12.
Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation.
Neuropharmacology
; 139: 85-97, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29981335
13.
Caged Naloxone: Synthesis, Characterization, and Stability of 3- O-(4,5-Dimethoxy-2-nitrophenyl)carboxymethyl Naloxone (CNV-NLX).
ACS Chem Neurosci
; 9(3): 563-567, 2018 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29154536
14.
Peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain.
Pain
; 159(9): 1814-1823, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-29781960
15.
Metabolic Profiling of CB1 Neutral Antagonists.
Methods Enzymol
; 593: 199-215, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28750803
16.
Synthesis and Physicochemical Characterization of the One-Carbon Carrier 10-Formyltetrahydrofolate; A Reference Standard for Metabolomics.
Metabolomics
; 13(10)2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29399009
17.
Peripherally Selective Cannabinoid 1 Receptor (CB1R) Agonists for the Treatment of Neuropathic Pain.
J Med Chem
; 59(16): 7525-43, 2016 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27482723
18.
Novel Synthesis and Pharmacological Characterization of NOP Receptor Agonist 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (Ro 64-6198).
ACS Chem Neurosci
; 6(12): 1956-64, 2015 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26367173
19.
Preparation of monoclonal antibodies reactive to the endogenous small molecule, anandamide.
J Immunol Methods
; 285(2): 181-95, 2004 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14980433
20.
Synthesis and structure-activity relationships of amide and hydrazide analogues of the cannabinoid CB(1) receptor antagonist N-(piperidinyl)- 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716).
J Med Chem
; 45(13): 2708-19, 2002 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12061874