Detalhe da pesquisa
1.
Pervasive lesion segregation shapes cancer genome evolution.
Nature
; 583(7815): 265-270, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32581361
2.
Mutational bias in spermatogonia impacts the anatomy of regulatory sites in the human genome.
Genome Res
; 31(11): 1994-2007, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417209
3.
Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions.
PLoS Genet
; 15(11): e1008480, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31765389
4.
A promoter-level mammalian expression atlas.
Nature
; 507(7493): 462-70, 2014 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24670764
5.
Clinical and molecular characterization of ovarian carcinoma displaying isolated lymph node relapse.
Am J Obstet Gynecol
; 221(3): 245.e1-245.e15, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31055034
6.
Mutational Biases Drive Elevated Rates of Substitution at Regulatory Sites across Cancer Types.
PLoS Genet
; 12(8): e1006207, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27490693
7.
Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations.
BMC Cancer
; 18(1): 16, 2018 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29298688
8.
Homozygous loss-of-function variants in European cosmopolitan and isolate populations.
Hum Mol Genet
; 24(19): 5464-74, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26173456
9.
Abundant local interactions in the 4p16.1 region suggest functional mechanisms underlying SLC2A9 associations with human serum uric acid.
Hum Mol Genet
; 23(19): 5061-8, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24821702
10.
Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation.
Mol Syst Biol
; 11(12): 852, 2015 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26700852
11.
Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response.
PLoS Comput Biol
; 11(4): e1004217, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25885578
12.
Posttranscriptional regulation of miRNAs harboring conserved terminal loops.
Mol Cell
; 32(3): 383-93, 2008 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18995836
13.
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.
Proc Natl Acad Sci U S A
; 109(16): E944-53, 2012 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22451944
14.
Genome-wide analysis of mammalian promoter architecture and evolution.
Nat Genet
; 38(6): 626-35, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16645617
15.
Widespread signatures of recent selection linked to nucleosome positioning in the human lineage.
Genome Res
; 21(11): 1777-87, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21903742
16.
Divergence of mammalian higher order chromatin structure is associated with developmental loci.
PLoS Comput Biol
; 9(4): e1003017, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23592965
17.
BiForce Toolbox: powerful high-throughput computational analysis of gene-gene interactions in genome-wide association studies.
Nucleic Acids Res
; 40(Web Server issue): W628-32, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22689639
18.
The genomic signature of trait-associated variants.
BMC Genomics
; 14: 108, 2013 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23418889
19.
High-throughput analysis of epistasis in genome-wide association studies with BiForce.
Bioinformatics
; 28(15): 1957-64, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22618535
20.
IMPROVE-DD: Integrating multiple phenotype resources optimizes variant evaluation in genetically determined developmental disorders.
HGG Adv
; 4(1): 100162, 2023 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36561149