Detalhe da pesquisa
1.
The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.
Cell
; 165(2): 382-95, 2016 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27040500
2.
RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.
Mol Cell
; 43(6): 950-61, 2011 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21925383
3.
Scaffold hopping towards potent and selective JAK3 inhibitors: discovery of novel C-5 substituted pyrrolopyrazines.
Bioorg Med Chem Lett
; 24(21): 4969-75, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25262541
4.
Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors.
Bioorg Med Chem Lett
; 23(9): 2522-6, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23541670
5.
Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): optimization for JNK potency and physicochemical properties.
Bioorg Med Chem Lett
; 23(12): 3565-9, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23664880
6.
Development of amino-pyrimidine inhibitors of c-Jun N-terminal kinase (JNK): kinase profiling guided optimization of a 1,2,3-benzotriazole lead.
Bioorg Med Chem Lett
; 23(5): 1486-92, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23352510
7.
Nanolitre-scale crystallization using acoustic liquid-transfer technology.
Acta Crystallogr D Biol Crystallogr
; 68(Pt 8): 893-900, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22868754
8.
Discovery of a novel series of 4-quinolone JNK inhibitors.
Bioorg Med Chem Lett
; 22(24): 7381-7, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23142618
9.
Acoustic matrix microseeding: improving protein crystal growth with minimal chemical bias.
Acta Crystallogr D Biol Crystallogr
; 66(Pt 5): 568-76, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20445232
10.
Suppressing nonsense--a surprising function for 5-azacytidine.
EMBO Mol Med
; 6(12): 1518-20, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25378479
11.
Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway.
Cell Rep
; 6(4): 748-64, 2014 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24529710
12.
3-Amido pyrrolopyrazine JAK kinase inhibitors: development of a JAK3 vs JAK1 selective inhibitor and evaluation in cellular and in vivo models.
J Med Chem
; 56(1): 345-56, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23214979