Detalhe da pesquisa
1.
Design, synthesis, and structure-activity relationships of a series of 2-Ar-8-methyl-5-alkylaminoquinolines as novel CRF1 receptor antagonists.
Bioorg Med Chem Lett
; 22(17): 5372-8, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22871582
2.
Design, synthesis and structure-activity relationships of 5-alkylaminolquinolines as a novel series of CRF1 receptor antagonists.
Bioorg Med Chem Lett
; 22(14): 4756-61, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22683343
3.
Synthesis and structure-activity relationships of 8-substituted-2-aryl-5-alkylaminoquinolines: Potent, orally active corticotropin-releasing factor-1 receptor antagonists.
Bioorg Med Chem
; 20(22): 6559-78, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23062820
4.
Selective corticotropin-releasing factor 1 receptor antagonist E2508 reduces restraint stress-induced defecation and visceral pain in rat models.
Psychoneuroendocrinology
; 75: 110-115, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27810704
5.
Selective corticotropin-releasing factor 1 receptor antagonist E2508 has potent antidepressant-like and anxiolytic-like properties in rodent models.
Behav Brain Res
; 312: 138-47, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27297028
6.
Synthesis and structure-activity relationships of pyrazolo[1,5-a]pyridine derivatives: potent and orally active antagonists of corticotropin-releasing factor 1 receptor.
J Med Chem
; 55(11): 5255-69, 2012 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22587443
7.
Design, synthesis, and structure-activity relationships of novel pyrazolo[5,1-b]thiazole derivatives as potent and orally active corticotropin-releasing factor 1 receptor antagonists.
J Med Chem
; 55(19): 8450-63, 2012 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22971011