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ABSTRACT: Shoemaker, ME, Smith, CM, Gillen, ZM, and Cramer, JT. Sex differences in test-retest reliability of near-infrared spectroscopy during postocclusive reactive hyperemia of the vastus lateralis. J Strength Cond Res 38(2): e40-e48, 2024-The purpose of this study was to determine test-retest reliability for vascular reactivity measures and ranges for normalization of near-infrared spectroscopy (NIRS) variables from the vastus lateralis using postocclusive reactive hyperemia (PORH) procedure in male subjects, female subjects, and combined. Concentrations of oxygenated hemoglobin (Hb) + myoglobin (Mb) (O 2 Hb) and deoxygenated Hb + Mb (HHb) to derive total Hb + Mb (THb), difference in Hb + Mb signal (Hbdiff), and muscle tissue oxygen saturation (StO 2 ) from the vastus lateralis were measured during the PORH in 12 male subjects (age: 23.17 ± 1.77 years; stature: 180.88 ± 4.59 cm; and mass: 81.47 ± 9.68 kg) and 10 female subjects (age: 23.80 ± 2.07 years; stature: 165.95 ± 4.92 cm; and mass: 70.93 ± 10.55 kg) on 2 separate days. Adipose tissue thickness at the NIRS site was measured with ultrasonography. There were no significant differences between the mean values from visit 1 to visit 2 ( p > 0.076-0.985). In the composite sample, intraclass correlation coefficient (ICC) and coefficient of variation (CV) ranged from 0.35 to 0.91 and 4.74 to 39.18%, respectively. In male subjects, ICC and CV values ranged from 0.57 to 0.89 and 2.44 to 28.55%, respectively. In female subjects, ICC and CV values ranged from -0.05 to 0.75 and 7.83 to 61.19%, respectively. Although NIRS variables were overall reliable during PORH, when separated by sex, reliability in male subjects generally increased, whereas female subjects were not reliable, suggesting adipose tissue thickness may be a contributing factor. Understanding sex differences in reliability is important when using this technique for normalization or examining vascular reactivity during athletic performance. With greater utilization of NIRS monitoring in athletes to examine training adaptations, it is important for practitioners to understand the capabilities and potential limitations of the tool.
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Hiperemia , Músculo Quadríceps , Humanos , Masculino , Feminino , Adulto Jovem , Adulto , Músculo Quadríceps/diagnóstico por imagem , Músculo Quadríceps/química , Espectroscopia de Luz Próxima ao Infravermelho/métodos , Hiperemia/metabolismo , Reprodutibilidade dos Testes , Caracteres Sexuais , Músculo Esquelético/metabolismo , Mioglobina/metabolismo , Consumo de Oxigênio/fisiologia , Oxigênio/metabolismoRESUMO
ABSTRACT: Gillen, ZM, Shoemaker, ME, McKay, BD, Bohannon, NA, Gibson, SM, and Cramer, JT. Influences of the stretch-shortening cycle and arm swing on vertical jump performance in children and adolescents. J Strength Cond Res 36(5): 1245-1256, 2022-This study compared the influences of the stretch-shortening cycle and arm swing on vertical jump performance during static jumps (SJs), counter-movement jumps (CMJs), and CMJs with arm swing (CMJAs) in young male and female athletes. Twenty-one boys (age = 12.1 ± 1.1 years) and 21 girls (age = 12.1 ± 1.1 years) performed SJs, CMJs, and CMJAs on force plates that sampled at 1 kHz. Measurements included peak force, rate of force development, peak power (PP), eccentric impulse (ECC), concentric impulse (CON), estimated jump height (JH), and changes in PP and JH across vertical jumps. Measurements of growth included age, maturity offset, height, body mass, fat-free mass, and thigh muscle cross-sectional area. Analyses of variance were used to analyze growth measurements across sex, as well as vertical jump outcome measures. Pearson product moment correlation coefficients were used to determine the relationships between changes in PP and JH across vertical jumps and growth measurements. There were differences in PP and JH such that SJ < CMJ < CMJA (p < 0.001), and ECC such that SJ < CMJA < CMJ (p ≤ 0.048). Changes in PP were greater from the SJ to CMJ than CMJ to CMJA (p ≤ 0.001). The change in PP from the SJ to CMJ exhibited moderate-to-high relationships with growth measurements for boys and girls (r = 0.543-0.803). Because young children may not have the skeletal musculature or strength necessary to absorb and reapply large eccentric preloading forces, future studies should consider using the CMJA, rather than the CMJ, to maximize vertical jump performance and minimize ECC. Coaches and practitioners can expect approximately 27-33% greater PP and 15-17% greater estimated JH when an arm swing is included during the CMJ.
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Desempenho Atlético , Força Muscular , Adolescente , Braço/fisiologia , Atletas , Desempenho Atlético/fisiologia , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Movimento/fisiologia , Força Muscular/fisiologia , Músculo Esquelético/fisiologiaRESUMO
PURPOSE: The purpose of this study was to compare measurements of muscle strength, size, and activation of the forearm flexors in pre- and post-pubescent males and females. METHODS: Forty pre-pubescent (mean ± 95% confidence interval, age = 9.79 ± 0.35 years, n = 10 males, n = 10 females) and post-pubescent (age = 17.23 ± 0.58 years, n = 10 males, n = 10 females) youth participated. Subjects completed maximal voluntary isometric contractions (MVICs) of the forearm flexors, and submaximal isometric step muscle actions at 30, 50, and 70% of the peak MVIC. Percent voluntary activation (VA) was quantified during all isometric muscle actions. Forearm flexor (biceps brachii and brachialis) muscle cross-sectional area (CSA) was quantified from ultrasound images. RESULTS: MVIC strength was expressed in absolute terms and normalized to CSA. Post-pubertal males were 130% stronger, had 101% greater CSA, and 17% greater maximal VA than pre-pubertal males, while post-pubertal females were 72% stronger, had 54% greater CSA, and 23% greater maximal VA than pre-pubertal females. When MVIC strength was normalized to CSA, the post-pubertal males were still 15% stronger than the pre-pubertal males, while the post-pubertal females were only 12% stronger than the pre-pubertal females. The responses for VA across intensity reflected differences in muscle activation strategies between pre- and post-pubertal males and females. CONCLUSION: These results suggest that muscle size may account for a greater proportion of the growth and development-related differences in strength among males, while females may be more affected by changes in muscle activation. Regardless of sex, changes in muscle size and neuromuscular function influence strength increases during growth and development.
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Força Muscular/fisiologia , Músculo Esquelético/anatomia & histologia , Músculo Esquelético/fisiologia , Puberdade/fisiologia , Adolescente , Criança , Feminino , Humanos , Masculino , Fatores SexuaisRESUMO
Objective: The purpose of this study was to determine the prevalence of poor iron status in young athletes throughout the stages of iron deficiency and assess sex differences with iron deficiency in relation to growth and development and dietary intake.Methods: A cross-sectional analysis evaluated young male and female athletes (n = 91) between the ages 8 and 16 years. Anthropometric assessments, body composition, dietary intakes, and blood samples measuring ferritin, soluble transferrin receptor (sTfR), and hemoglobin (Hb) were examined. Prevalence was calculated as percentages, and independent samples t tests examined sex differences. Pearson product-moment correlation coefficient analyses quantified relationships among variables for the composite sample and each sex separately.Results: Iron depletion (low ferritin) was present in 65% and 86%, low iron levels (sTfR) in 51% and 68%, and anemia (low Hb) in 46% and 53% of the males and females, respectively. As iron deficiency progressed from low ferritin to high sTfR to anemia, prevalence decreased in both sexes, but always remained higher in females. Males were greater than females for weight, arm muscle size, and ferritin concentrations, while females were greater than males for biological maturity (p ≤ 0.05). Dietary iron intake was moderately to highly correlated (r = 0.543-0.723, p ≤ 0.05) with growth and development in females, but not males.Conclusions: Prevalence of poor iron status was higher than expected, particularly in adolescent females. Since rapid growth combined with sports participation may create high demands for iron bioavailability, emphasis may need to be placed on dietary iron intake for young athletes, particularly females.
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Anemia Ferropriva/epidemiologia , Atletas/estatística & dados numéricos , Biomarcadores/sangue , Crescimento e Desenvolvimento/fisiologia , Deficiências de Ferro , Ferro da Dieta/administração & dosagem , Adolescente , Anemia Ferropriva/sangue , Anemia Ferropriva/diagnóstico , Criança , Estudos Transversais , Dieta , Feminino , Ferritinas/sangue , Hemoglobinas/análise , Humanos , Masculino , Estado Nutricional/fisiologia , Receptores da Transferrina/sangue , Fatores SexuaisRESUMO
Bohannon, NA, Gillen, ZM, Shoemaker, ME, McKay, BD, Gibson, SM, Cramer, JT. Test-Retest Reliability of Static and Counter-Movement Power Push-Up Tests in Young Male Athletes. J Strength Cond Res 34(9): 2456-2464, 2020-The primary purpose of this study was to evaluate test-retest reliability of the static (SP) and countermovement (CMP) power push-up test in young male athletes. The secondary purpose was to compare the reliability of vertical ground reaction forces versus torque measurements during the power push-up tests. Twenty boys (age = 11.60 ± 1.15 years) performed SPs and CMPs on force plates with the knees as the fulcrum on 2 laboratory visits separated by 2-7 days. Performance measurements included peak force (PF), peak rate of force development (pRFD), peak torque (PT), peak rate of torque development (pRTD), peak power (PP), average power (AP), eccentric impulse (ECC), and concentric impulse (CON) for both power push-up techniques. Age, maturity offset, height, body mass, fat-free mass, and estimated arm cross sectional area were obtained as measurements of growth. Intraclass correlation coefficients (ICC), SEM, coefficients of variation, and minimum detectable changes (MDC) were reported. Only PF (ICC = 0.87-0.88, SEM = 59-84 N) and PT (ICC = 0.89-0.90, SEM = 60-88 N·m) showed acceptable reliability. Neither pRFD, pRTD, PP, AP, ECC, or CON were reliable outcomes. There were no meaningful differences between force-time and torque-time curve measurements. The SP showed slightly lower CVs (33-34%) than the CMP (CVs = 39-40%). Coaches and practitioners would need to see 58-71% increases in upper-body strength measurements evaluated via power push-up on force plates to be 95% confident that the improvements exceeded the measurement variability.
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Atletas , Teste de Esforço/métodos , Força Muscular/fisiologia , Adolescente , Criança , Humanos , Masculino , Reprodutibilidade dos Testes , TorqueRESUMO
Gillen, ZM, Shoemaker, ME, McKay, BD, Bohannon, NA, Gibson, SM, and Cramer, JT. Peak torque explains more unique variability in growth measurements than rate of torque development in young boys and girls. J Strength Cond Res 34(9): 2507-2514, 2020-This study reported test-retest reliability and evaluated collinearity for isometric leg extension and flexion peak torque (PT) and rate of torque development (RTD) in young boys and girls. Measurements of growth included height, body mass, fat-free mass, maturity offset, and leg extensor and flexor muscle cross-sectional area. Maximal isometric contractions quantified PT and RTD. Intraclass correlation coefficients (ICCs), SEM, coefficients of variation, and minimum detectable changes quantified test-retest reliability. Zero-order correlations and first-order partial correlations evaluated collinearity. Peak torque from leg extension and flexion exhibited ICCs ≥ 0.90, RTD from leg extension and flexion exhibited ICCs ≥ 0.38. Partialing out leg flexion PT reduced the relationships between leg extension PT and growth (rPText, growth.PTflex = 0.392-0.605). Partialing out leg extension PT eliminated the relationships between leg flexion PT and growth (rPTflex, growth.PText = 0.098-0.263). Partialing out leg extension RTD reduced the relationships between PT and growth (rPText, growth.RTDext = 0.516-0.775). Partialing out leg extension PT eliminated the relationships between RTD and growth (|rRTDext, growth.PText| = 0.001-0.148). Leg extension PT was more reliable and explained the most unique variability in growth among young boys and girls. In contrast, RTD was less reliable and was fully accounted for by PT, indicating that RTD may be an unnecessary measurement in studies of young boys and girls.
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Desenvolvimento do Adolescente/fisiologia , Desenvolvimento Infantil/fisiologia , Força Muscular/fisiologia , Músculo Esquelético/fisiologia , Torque , Adolescente , Pesos e Medidas Corporais , Criança , Estudos Transversais , Feminino , Humanos , Contração Isométrica/fisiologia , Masculino , Reprodutibilidade dos TestesRESUMO
PURPOSE: To compare measurements of muscle strength, size, and neuromuscular function among pre-adolescent and adolescent boys and girls with distinctly different strength capabilities. METHODS: Fifteen boys (mean age ± confidence interval: 13.0 ± 1.0 years) and 13 girls (12.9 ± 1.1 years) were categorized as low strength (LS, n = 14) or high strength (HS, n = 14) based on isometric maximal voluntary contraction strength of the leg extensors. Height (HT), seated height, and weight (WT) determined maturity offset, while percent body fat and fat-free mass (FFM) were estimated from skinfold measurements. Quadriceps femoris muscle cross-sectional area (CSA) was assessed from ultrasound images. Isometric ramp contractions of the leg extensors were performed while surface electromyographic amplitude (EMGRMS) and mechanomyographic amplitude (MMGRMS) were recorded for the vastus lateralis (VL). Neuromuscular efficiency from the EMG and MMG signals (NMEEMG and NMEMMG, respectively) and log-transformed EMG and MMG vs. torque relationships were also used to examine neuromuscular responses. RESULTS: HS was 99-117% stronger, 2.3-2.8 years older, 14.0-15.7 cm taller, 20.9-22.3 kg heavier, 2.3-2.4 years more biologically mature, and exhibited 39-43% greater CSA than LS (p ≤ 0.001). HS exhibited 74-81% higher NMEEMG than LS (p ≤ 0.022), while HS girls exhibited the highest NMEMMG (p ≤ 0.045). Even after scaling for HT, WT, CSA, and FFM, strength was still 36-90% greater for HS than LS (p ≤ 0.031). The MMGRMS patterns in the LS group displayed more type I motor unit characteristics. CONCLUSIONS: Neuromuscular adaptations likely influence strength increases from pre-adolescence to adolescence, particularly when examining large, force-producing muscles and large strength differences explained by biological maturity, rather than simply age.
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Força Muscular , Músculo Esquelético/crescimento & desenvolvimento , Adolescente , Criança , Feminino , Humanos , Contração Isométrica , Masculino , Músculo Esquelético/diagnóstico por imagem , Músculo Esquelético/fisiologiaRESUMO
This study measured peak force (PF), peak rate of force development (PRFD), peak power (PP), concentric impulse, and eccentric impulse during static jump (SJ), countermovement jump (CMJ), and drop jump (DJ) in youth athletes to examine changes in vertical jump power with progressively greater eccentric preloading in relation to age, maturity, and muscle mass. Twenty-one males ranging from 6 to 16 years old performed the following vertical jumps in a random order: SJ, CMJ, and DJ from drop heights of 20, 30, and 40 cm (DJ20, DJ30, and DJ40, respectively). Measurements included PF, PRFD, PP, eccentric impulse, and concentric impulse for each vertical jump condition. Maturity offset was calculated, while ultrasound images quantified thigh muscle cross-sectional area (CSA). PF and PRFD increased from CMJ to DJ20. PP increased from SJ to CMJ. Concentric impulse remained unchanged, but eccentric impulse increased systematically from across jumps. The change in PP from SJ to CMJ was correlated with age, height, weight, maturity offset, and CSA. The CMJ resulted in the greatest concentric PP with the least amount of eccentric preloading. The inability of young athletes to translate the energy absorbed during the eccentric phase of the stretch-shortening cycle of DJs may be influenced by growth and development.
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Desempenho Atlético/fisiologia , Força Muscular , Músculo Esquelético/fisiologia , Adolescente , Atletas , Criança , Estudos Transversais , Teste de Esforço , Humanos , Masculino , Coxa da PernaRESUMO
College athletes, especially in weight class sports, often experience energy deficits. Athletes competing in weight class sports such as wrestling are at greatest risk for deficiencies and little is known about the relationships between body composition, nutrient intake, and performance in these athletes. The purposes of this study were to (1) quantify macronutrient and micronutrient intake of pre-season male collegiate wrestlers and compare to estimated needs, and (2) examine relationships among nutritional intakes, body composition, and performance measurements of strength and anaerobic capacity. Male Division I wrestlers (n = 11, age: 21.3 ± 1.7 years, wrestling experience: 14.9 ± 2.5 years) were recruited during pre-season. Nutrient intake was collected from a 3-day food diary. A 7-site skinfold assessment determined fat-free mass (FFM) to estimate total daily energy expenditure (eTEE). Isokinetic and isometric strength were evaluated by a Biodex dynamometer. Anaerobic capacity was tested on a stationary cycle ergometer. Eight of eleven wrestlers were energy deficient based on estimated needs. Mean intake of four micronutrients fell below the Recommended Dietary Allowances (RDA). Significant correlations were found between dietary intake, strength and anaerobic performance variables (r = 0.603 - 0.902, p = 0.0001 - 0.05). However, after accounting for FFM, these relationships were no longer significant. Nutrient intake in tandem with body composition affects performance for weight class athletes. Achieving high FFM during the preseason may be advantageous for wrestling performance. Nutrient intake and body composition should be monitored so coaches and health professionals can create individualized recommendations to help athletes optimize performance.
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BACKGROUND: Testing and evaluating athletes is necessary and should include performance, body composition, and nutrition. The purpose of this study was to report assessments of dietary intake, VËO2max, and body composition in D1 collegiate athletes and examine relationships between these assessments. METHODS: Dietary intake was assessed with 3-day recalls and compared to recommendations, and body composition was assessed via bioelectrical impedance analysis (BIA) (n = 48). VËO2max was evaluated using a graded exercise test (GXT) with a verification bout (n = 35). Reliability between "true" VËO2max and verification was determined. Correlations and regressions were performed. RESULTS: Energy, carbohydrate, and micronutrient intake was lower than recommendations. Mean VËO2max was 47.3 and 47.4 mL·kg-1·min-1 for GXT and verification, respectively. While correlations were apparent among dietary intake, VËO2max, and body composition, percent fat-free mass (%FFM) predicted 36% of VËO2max. CONCLUSIONS: Collegiate athletes are not meeting energy and carbohydrate recommendations and exceed fat recommendations. Vitamin D and magnesium were low in all sports, and iron and calcium were low in females. VËO2max ranged from 35.6 to 63.0 mL·kg-1·min-1, with females below average and males meeting typical values for their designated sport. Assessing D1 athletes can provide guidance for sports dietitians, coaches, and strength and conditioning specialists to track and monitor nutrition in athletes.
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Atletas , Composição Corporal , Estado Nutricional , Humanos , Feminino , Masculino , Adulto Jovem , Desempenho Atlético/fisiologia , Ingestão de Energia , Consumo de Oxigênio/fisiologia , Universidades , Adolescente , Impedância Elétrica , Carboidratos da Dieta/administração & dosagem , Avaliação Nutricional , Teste de Esforço/métodos , Dieta , Fenômenos Fisiológicos da Nutrição EsportivaRESUMO
Metabolic flexibility can be defined as the ability of the skeletal muscle to adjust its utilization of substrate pathways [...].
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Introduction: Police officers must perform various tasks in unpredictable work environments and potentially volatile situations. This study aimed to determine if cardiovascular fitness, body composition, and physical activity levels could predict performance in a Midwest Police Department's Physical Readiness Assessment (PRA). Methods: Researchers collected data from thirty incumbent police officers (33.9 ± 8.3 years, female = 5). Anthropometric data included height, body mass, body fat percentage (BF%), fat-free mass (FFM), and maximal hand grip strength. The police officers also completed a physical activity rating (PA-R) scale to estimate maximal oxygen consumption (VËO2max) and the International Physical Activity Questionnaire (IPAQ). Police officers then conducted their department's PRA. Stepwise linear regression analyses were used to determine the relationship between predictor variables and PRA performance. Pearson's product-moment correlations investigated relationships between anthropometric, physical fitness, and physical activity variables and PRA performance using SPSS (v.28). The significance level was set at p < 0.05. Results: Descriptive data for the sample includes BF%: 27.85 ± 7.57%, FFM: 65.73 ± 10.72 kg, hand grip strength: 55.51 ± 11.07 kg, weekday sedentary time (WST): 328 ± 28.26 min, weekend day sedentary time (WDST): 310 ± 28.92 min, daily moderate-to-vigorous physical activity (MVPA): 29.02 ± 39.41 min, PRA: 273.6 ± 51.4 s and estimated VËO2max: 43.26 ± 6.35 mL kg-1 min-1. The stepwise regression analyses indicated that BF% was predictive of PRA time (R2 = 0.32, p < 0.01); estimated VËO2max predictive of PRA time (R2 = 0.45, p < 0.001). There were significant correlations between BF % and PRA time (r = 0.57, p < 0.001), PA-R and MVPA (r = 0.71, p < 0.001), %BF % and WDST (r = -0.606, p < 0.001), hand grip and FFM (r = 0.602, p < 0.001) and PA-R and PRA time (r = -0.36, p < 0.05). Discussion: The results of this exploratory study highlight that higher estimated VËO2max and lower BF% were the best predictors for faster PRA completion times, accounting for 45% and 32% of the variance, respectively. The findings of this study support the need for wellness and fitness initiatives in law enforcement agencies focused on increasing cardiovascular fitness and physical activity while decreasing BF% to ensure optimal performance in policing and overall health.
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Força da Mão , Polícia , Humanos , Feminino , Exercício Físico , Aptidão Física , Composição CorporalRESUMO
There is conflicting evidence of the roles vitamin D and iron have in isolation and combined in relation to muscle health. The purpose of this narrative review was to examine the current literature on the roles that vitamin D and iron have on skeletal muscle mass, strength, and function and how these nutrients are associated with skeletal muscle health in specific populations. Secondary purposes include exploring if low vitamin D and iron status are interrelated with skeletal muscle health and chronic inflammation and reviewing the influence of animal-source foods rich in these nutrients on health and performance. PubMed, Scopus, SPORT Discus, EMBAE, MEDLINE, and Google Scholar databases were searched to determine eligible studies. There was a positive effect of vitamin D on muscle mass, particularly in older adults. There was a positive effect of iron on aerobic and anaerobic performance. Studies reported mixed results for both vitamin D and iron on muscle strength and function. While vitamin D and iron deficiency commonly occur in combination, few studies examined effects on skeletal muscle health and inflammation. Isolated nutrients such as iron and vitamin D may have positive outcomes; however, nutrients within food sources may be most effective in improving skeletal muscle health.
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Deficiência de Vitamina D , Vitamina D , Animais , Suplementos Nutricionais , Inflamação , Ferro , Força Muscular/fisiologia , Músculo Esquelético/fisiologia , VitaminasRESUMO
Malnutrition and sarcopenia commonly overlap and contribute to adverse health outcomes. Previously, chronic supplementation with two oral nutritional supplements (ONS), control (CONS) and experimental ONS enriched with protein, vitamin D and ß-hydroxy ß-methylbutyrate (HMB) (EONS), improved muscle strength and quality in malnourished sarcopenic older adults, with EONS demonstrating early strength benefits at 12 weeks. To understand the underlying biological mechanisms contributing to the observed early strength benefits of EONS, we examined serum biomarker changes in response to 12-week supplementation. Serum samples (EONS (n = 90) and CONS (n = 103)) collected at baseline and 12 weeks were analyzed. Biomarkers (n = 243) were measured using multiplexed immunoassay, commercial immunoassays and ELISAs. Sixty markers were excluded with levels below assay detection limits. Sixteen biomarkers significantly changed in response to both interventions including nutritional and metabolic markers. Thirteen biomarkers significantly changed in response to EONS but not CONS. Increases in immunoglobulins, myoglobin, total protein, vitamin E and magnesium were observed with EONS. Inflammation-related ferritin and osteopontin decreased, while soluble receptors for cytokines increased, suggesting decreased inflammation. Sex hormone-binding globulin associated with sarcopenia also decreased with EONS. Biomarkers reflective of multiple biological systems were impacted by nutritional intervention in sarcopenic older adults. Incremental biomarker changes were observed in response to EONS containing HMB that possibly link to improvements in skeletal muscle health.
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Desnutrição , Sarcopenia , Idoso , Biomarcadores , Suplementos Nutricionais , Humanos , Vida Independente , Vitamina DRESUMO
Little is known about potential protective factors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), referred to as COVID-19. Suboptimal vitamin D status is a risk factor for immune dysfunction, respiratory tract infections (RTIs), and viral infections. Supplementation of vitamin D (2000-4000 IU) has decreased incidence and complications from RTIs, respiratory distress syndrome, and pneumonia and may be beneficial in high-risk populations. Given the possible link between low vitamin D status and RTIs, such as COVID-19, this review examined whether vitamin D supplementation can be supported as a nutritional strategy for reducing risk of infection, complications, and mortality from COVID-19 and found that the relationship between vitamin D and RTIs warrants further exploration.
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BACKGROUND: Metabolic flexibility is the ability of skeletal muscle to adapt fuel utilization to the demand for fuel sources [carbohydrates (CHO) and fats (FAT)]. The purpose of this study was to explore muscle energy metabolism and metabolic flexibility under various conditions in sarcopenic (S) versus nonsarcopenic (NS) older adults. METHODS: Twenty-two older adults aged 65 years or older were categorized as NS [n = 11; mean ± standard deviation (SD); age = 73.5 ± 6.0 years (males, n = 5; females, n = 6)] or S [n = 11; 81.2 ± 10.5 years (males, n = 6; females, n = 5) based on handgrip strength, body composition and physical performance. Indirect calorimetry was recorded before and after consumption of a high-CHO meal and during aerobic and anaerobic exercise. Respiratory quotient (RQ), CHO and FAT oxidation were assessed. Venous blood samples were collected for glucose and insulin concentrations. RESULTS: At rest, compared with NS, S exhibited a 5-8% higher RQ at 0 (0.72 vs. 0.76) and 120 (0.77 vs. 0.82), 150 (0.76 vs. 0.80), and 180 min (0.74 vs. 0.80) (P = 0.002-0.025); 59-195% higher CHO oxidation at 0, 120, and 180 min (0.0004-0.002 vs. 0.001-0.002 g·min-1 ·kg-1) (P = 0.010-0.047); and 20-31% lower FAT oxidation at 0, 15, and 90-180 min (0.0009-0.0022 vs. 0.0011-0.002 g·min-1 ·kg-1 ) (P = 0.004-0.038). Glucose levels were significantly elevated in S versus NS at 0, 60 and 75 min (144.64-202.78 vs. 107.70-134.20 mg·dL-1 ) but not insulin. During aerobic exercise, RQ was 5% greater (0.90 vs. 0.86) (P = 0.039), and FAT oxidation was 35% lower at 6-8 min (0.003 vs. 0.005 g·min-1 ·kg-1 ) (P = 0.033) in S versus NS. During anaerobic exercise, CHO oxidation was 31% greater in NS versus S at 60-80% time to exhaustion (0.011 vs. 0.007 g·min-1 ·kg-1 ) (P = 0.015). Per cent contribution to energy expenditure was greater in S for CHO but lower for FAT at 0 (CHO: 22% vs. 10%; FAT: 78% vs. 91%) and 120-180 min (CHO: 35-42% vs. 17-25%; FAT: 58-65% vs. 75%-84%) (P = 0.003-0.046) at rest and 6-8 min during aerobic exercise (CHO: 70% vs. 57%; FAT: 30% vs. 45%) (P = 0.046). CONCLUSIONS: The data show differences in skeletal muscle energy metabolism and substrate utilization between S and NS at rest, transitioning from fasted to fed state, and during exercise. Compared with NS, S displayed a diminished ability to adapt fuel utilization in response to feeding and exercise, reflecting metabolic inflexibility. Impaired metabolic flexibility could be a mechanism underlying the losses of strength and physical function accompanying sarcopenia.
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Sarcopenia , Idoso , Metabolismo Energético/fisiologia , Exercício Físico/fisiologia , Feminino , Força da Mão , Humanos , Masculino , Músculo Esquelético/metabolismo , Sarcopenia/metabolismoRESUMO
BACKGROUND & AIMS: Consumption of rapid digesting sugars by children are under increased scrutiny because of their contribution to unhealthy weight gain. Previous studies in adults and children have suggested that altering the blend of carbohydrates (CHOs) consumed may cause shifts in substrate utilization. The purpose of this study was to examine the effects of consuming a slow digesting carbohydrate (SDC) and rapid digesting carbohydrate (RDC) on CHO and fat oxidation, glucose, and insulin responses at rest, during exercise, and post-exercise rest in pre-pubescent children. METHODS: A randomized, double-blind, crossover design was used. Nineteen pre-pubescent children (n = 10 boys, n = 9 girls, mean ± standard error, age = 9.84 ± 0.37-yrs) participated. Visits to the laboratory began with a 30-min measurement of resting metabolism followed by consumption of either an RDC or SDC drink. Postprandial resting metabolism was recorded for 60-min, immediately followed by 60-min of submaximal cycling exercise while metabolism was recorded, which was immediately followed by another 60-min recording of post-exercise metabolism. Total CHO and fat oxidation, endogenous and exogenous CHO oxidation, blood glucose, and insulin were assessed. RESULTS: Total CHO oxidation rate (gâmin-1) was greater after the RDC drink at 60 min (p = 0.032). Endogenous CHO oxidation rate (gâmin-1) was greater after the SDC drink at 15 min (p ≤ 0.010). Cumulative endogenous CHO oxidation (g) was greater after the SDC drink at 45 min (p = 0.009). Endogenous CHO oxidation accounted for a greater proportion of substrate oxidation after the first 60-min rest period (p = 0.028), while exogenous CHO oxidation accounted for a greater proportion of substrate oxidation for the RDC at all time points (p ≤ 0.019). CONCLUSIONS: The present study provides novel data suggesting that an SDC promotes greater endogenous substrate utilization in pre-pubertal children, which may have beneficial health impacts on energy intake and carbohydrate regulation/metabolism during growth and development. CLINICAL TRIALS REGISTRY NUMBER: NCT03185884, clinicaltrials.gov.
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Metabolismo dos Carboidratos , Carboidratos da Dieta/metabolismo , Metabolismo Energético , Oxirredução , Glicemia/metabolismo , Criança , Estudos Cross-Over , Gorduras na Dieta/metabolismo , Método Duplo-Cego , Exercício Físico , Feminino , Humanos , Insulina/metabolismo , Masculino , Consumo de Oxigênio , Período Pós-PrandialRESUMO
The purpose of this study was to use polynomial regression analyses to examine the torque- and power-velocity relationships and calculate and compare the vertices of these nonlinear models, and how they relate to measurements of muscle size and maximal strength, between male and female children and adolescents during maximal isokinetic leg extension muscle actions. Sixteen children (n = 8 males, n = 8 females) and 22 adolescents (n = 11 males, n = 11 females) participated in this study. Measurements of growth included age, maturity offset, height, body mass, fat-free mass, and quadriceps femoris muscle cross-sectional area (CSA). Participants completed maximal voluntary isometric contractions (MVICs) of the leg extensors and maximal voluntary isokinetic leg extensions at 60, 120, 180, 240, and 300°·s-1. Variables calculated during all leg extension muscle actions included peak torque (PT, Nm) and mean power (MP, W). Polynomial regression analyses determined the model of best fit for the PT- and MP-velocity relationships. For each participant, the vertex from the PT- and MP-velocity quadratic models were quantified as the predicted maximum velocity of last measurable torque (VPT) and the predicted velocity of maximum mean power (VMP), respectively. Measurements of growth, PT and MP at all velocities, VPT, and VMP were greater in the adolescents than children. When normalized to CSA, VPT and VMP remained greater for adolescents than children, and exhibited low to very high relationships with measurements of growth. When normalized to MVIC strength, VPT and VMP were no longer different between children and adolescents and exhibited negligible to low relationships with measurements of growth. The results of the present study suggest that the ability to produce torque and power at high velocities may be more dependent on muscle strength than muscle size, which suggests that mechanisms other than muscular hypertrophy affect torque and power production at high velocities in young males and females.
Assuntos
Contração Isométrica/fisiologia , Perna (Membro)/anatomia & histologia , Perna (Membro)/fisiologia , Músculo Quadríceps/anatomia & histologia , Músculo Quadríceps/fisiologia , Torque , Adolescente , Envelhecimento/fisiologia , Fenômenos Biomecânicos/fisiologia , Estatura , Peso Corporal , Criança , Feminino , Humanos , Masculino , Força Muscular , Dinâmica não LinearRESUMO
PURPOSE: The purposes of the present study were to (a) examine resting metabolism, substrate utilization, and endogenous versus exogenous carbohydrate (CHO) oxidation before and after 30-g rapidly-digesting carbohydrate (RDC) ingestion using indirect calorimetry and breath test analysis of stable isotope concentrations in pre-pubescent children and (b) report the 13C abundances in foods consumed for three days prior. METHODS: Nineteen children (n = 10 boys, n = 9 girls) at Tanner stage I or II participated (mean age ± 95% CI = 9.84 ± 0.77 y) in this study. Food was administered to the children for three days preceding their scheduled breath tests. Breath tests and indirect calorimetry were performed after an 8-h fast before and 60 min following consumption of a 30-g simple RDC drink consisting of maltodextrin and sucrose. Open circuit spirometry and indirect calorimetry monitored resting metabolism and CHO oxidation. Separate breath samples were taken every 15 min. Samples of all foods and breath samples were analyzed for 13C and 12C abundances with a stable-isotope mass spectrometer. RESULTS: 13C in expired breath samples were -23.81 ± 1.64 at baseline and increased every 15 min after consumption of the CHO drink (p < 0.001-0.009). Cumulative total, endogenous, and exogenous CHO utilization increased during the post-prandial period (p < 0.001). Endogenous CHO oxidation was consistently greater than exogenous CHO oxidation (p < 0.001-0.002).Blood glucose was elevated from baseline at 30- and 60-min post-prandial (p < 0.001). Insulin did not change over time (p = 0.184). CONCLUSIONS: The foods provided during the 3-day controlled diet effectively minimized 13C variation prior to metabolic testing. The 13C abundances of foods reported herein should serve as practical recommendations to reduce 13C intake before breath tests. While endogenous CHO oxidation remained greater in proportion to exogenous CHO oxidation, these findings suggest that even a relatively small amount of RDC can increase exogenous CHO oxidation and blood glucose in normal-weight children. To further examine shifts in endogenous versus exogenous CHO utilization, we recommend that future studies take steps to minimize 13C variation before breath tests and examine changes in substrate metabolism at rest and during exercise in normal weight and overweight pre-pubescent children. CLINICAL TRIAL REGISTRATION NUMBER: NCT03185884.
RESUMO
PURPOSE: The purpose of this study was to determine magnitudes of differences for anthropometric and athletic performance scores between high school and elite college-level American football players. METHOD: Participants included high school-age (n = 3,666) athletes who participated in American football combines, as well as elite college-level (n = 5,537) athletes who participated in the National Football League (NFL) scouting combine. Combine data included position; height; weight; 10-, 20-, and 40-yard dash; pro-agility (PA); L-cone drill (LC); vertical jump (VJ); and broad jump (BJ). Athletes were separated into their respective position group, defensive back (DB), wide receiver (WR), linebacker (LB), quarterback (QB), running back (RB), tight end (TE), defensive line (DL), and offensive line (OL) for analysis of performance differences. Percent differences for each dependent variable were calculated to quantify magnitudes of differences. RESULTS: NFL combine participants scored 3% to 25% better on all measurements, with the largest differences between weight and VJ (14%-25%). CONCLUSION: The largest measurement-specific differences between high school-age and elite college-level American football players were body size and power. Although it may seem intuitive that elite college-level players would perform better, these data provide a unique perspective to high school players, parents, and coaches, giving new information to use when designing measurement-specific athletic development programs. Thus, strength and conditioning professionals may benefit from emphasizing increases in muscle mass and power output in strength and conditioning programs.