Pilot evaluation of an interactive multimedia platform to provide nutrition education to Portuguese adolescents.

BACKGROUND: Obesity prevalence has been rising worldwide and currently is one of the most serious public health problems. Nutrition literacy is important to the development of healthier habits that could help prevent and stem obesity and overweight. The aim of this study was to evaluate the impact of using a multimedia web platform to provide nutrition education to Portuguese adolescents. METHODS: The intervention consisted in a two-week period in which students (n = 1291) had access to an interactive multimedia web platform with nutritional content, and designed for a self-paced learning experience. Students completed a knowledge questionnaire at baseline and immediately after the end of the intervention. RESULTS: The results obtained revealed that 85.8% of the students increased their nutrition knowledge. No gender differences were observed post-intervention. There were significant differences in the knowledge acquisition regarding age (P < 0.001). The baseline knowledge seemed to influence the learning process. CONCLUSIONS: Overall, the intervention had a positive impact. The preliminary results observed will be important for the improvement of the intervention, though they need to be confirmed by further research. Nevertheless, it is safe to say that technology-based assets can be important tools to incorporate and complement health-related interventions in schools.

Anaerobic Threshold Biophysical Characterisation of the Four Swimming Techniques.

The anaerobic threshold (AnT) seems to be not only a physiologic boundary but also a transition after which swimmers technique changes, modifying their biomechanical behaviour. We expanded the AnT concept to a biophysical construct in the four conventional swimming techniques. Seventy-two elite swimmers performed a 5×200 m incremental protocol in their preferred swimming technique (with a 0.05 m·s-1 increase and a 30 s interval between steps). A capillary blood samples were collected from the fingertip and stroke rate (SR) and length (SL) determined for the assessment of [La], SR and SL vs. velocity inflexion points (using the interception of a pair of linear and exponential regression curves). The [La] values at the AnT were 3.3±1.0, 3.9±1.1, 2.9±1 .34 and 4.5±1.4 mmol·l-1 (mean±SD) for front crawl, backstroke, breaststroke and butterfly, and its corresponding velocity correlated highly with those at SR and SL inflection points (r=0.91-0.99, p<0.001). The agreement analyses confirmed that AnT represents a biophysical boundary in the four competitive swimming techniques and can be determined individually using [La] and/or SR/SL. Blood lactate increase speed can help characterise swimmers' anaerobic behaviour after AnT and between competitive swimming techniques.

On the nature of the solvated electron in ice Ih.

The water-solvated excess electron (EE) is a key chemical agent whose hallmark signature, its asymmetric optical absorption spectrum, continues to be a topic of debate. While nearly all investigation has focused on the liquid-water solvent, the fact that the crystalline-water solvated EE shows a very similar visible absorption pattern has remained largely unexplored. Here, we present spin-polarized density-functional theory calculations subject to periodic boundary conditions of the interplay between an EE and a number of intrinsic lattice defects in ice Ih. Our results show that the optical absorption signatures in the presence of three unsaturated hydrogen bonds (HB) are very similar to those observed experimentally. Its low-energy side can be attributed to transitions between the EE ground state and a single localized excited level, in a picture that is different from that for the liquid solvent, where this portion has been associated with hydrogen-like s → p excitations. The blue tail, on the other hand, relates to transitions between the EE ground state and delocalized excited states, which is in line with the bound-to-continuum transition interpretations for the EE in liquid water. Finally, we find that, depending on the number of dangling HBs participating in the EE trap, its charge density may spontaneously break the spin degeneracy through exchange interactions with the surrounding electrons, displaying the many-electron quantum nature of the EE problem in ice Ih.

Cyclic nucleotide-dependent relaxation pathways in vascular smooth muscle.

Vascular smooth muscle tone is controlled by a balance between the cellular signaling pathways that mediate the generation of force (vasoconstriction) and release of force (vasodilation). The initiation of force is associated with increases in intracellular calcium concentrations, activation of myosin light-chain kinase, increases in the phosphorylation of the regulatory myosin light chains, and actin-myosin crossbridge cycling. There are, however, several signaling pathways modulating Ca(2+) mobilization and Ca(2+) sensitivity of the contractile machinery that secondarily regulate the contractile response of vascular smooth muscle to receptor agonists. Among these regulatory mechanisms involved in the physiological regulation of vascular tone are the cyclic nucleotides (cAMP and cGMP), which are considered the main messengers that mediate vasodilation under physiological conditions. At least four distinct mechanisms are currently thought to be involved in the vasodilator effect of cyclic nucleotides and their dependent protein kinases: (1) the decrease in cytosolic calcium concentration ([Ca(2+)]c), (2) the hyperpolarization of the smooth muscle cell membrane potential, (3) the reduction in the sensitivity of the contractile machinery by decreasing the [Ca(2+)]c sensitivity of myosin light-chain phosphorylation, and (4) the reduction in the sensitivity of the contractile machinery by uncoupling contraction from myosin light-chain phosphorylation. This review focuses on each of these mechanisms involved in cyclic nucleotide-dependent relaxation of vascular smooth muscle under physiological conditions.

Resultant equations for training load monitoring during a standard microcycle in sub-elite youth football: a principal components approach.

Applying data-reduction techniques to extract meaningful information from electronic performance and tracking systems (EPTS) has become a hot topic in football training load (TL) monitoring. The aim of this study was to reduce the dimensionality of the internal and external load measures, by a principal component approach, to describe and explain the resultant equations for TL monitoring during a standard in-season microcycle in sub-elite youth football. Additionally, it is intended to identify the most representative measure for each principal component. A principal component analysis (PCA) was conducted with a Monte Carlo parallel analysis and VariMax rotation to extract baseline characteristics, external TL, heart rate (HR)-based measures and perceived exertion. Training data were collected from sixty sub-elite young football players during a 6-week training period using 18 Hz global positioning system (GPS) with inertial sensors, 1 Hz short-range telemetry system, total quality recovery (TQR) and rating of perceived exertion (RPE). Five principal components accounted for 68.7% of the total variance explained in the training data. Resultant equations from PCA was subdivided into: (1) explosiveness, accelerations and impacts (27.4%); (2) high-speed running (16.2%); (3) HR-based measures (10.0%); (4) baseline characteristics (8.3%); and (5) average running velocity (6.7%). Considering the highest factor in each principal component, decelerations (PCA 1), sprint distance (PCA 2), average HR (PCA 3), chronological age (PCA 4) and maximal speed (PCA 5) are the conditional dimension to be considered in TL monitoring during a standard microcycle in sub-elite youth football players. Current research provides the first composite equations to extract the most representative components during a standard in-season microcycle in sub-elite youth football players. Futures research should expand the resultant equations within training days, by considering other well-being measures, technical-tactical skills and match-related contextual factors.

Non-genomic vasorelaxant effects of 17ß-estradiol and progesterone in rat aorta are mediated by L-type Ca2+ current inhibition.

AIM: The sex hormones 17ß-estradiol (ßES) and progesterone (PRG) induce rapid non-genomic vasodilator effects which could be protective for the cardiovascular system. The purpose of this study was to analyze the mechanisms underlying their vasodilator effect in rat aortic smooth muscle preparations. METHODS: Endothelium-denuded aorta artery rings were prepared from male Wistar rats and incubated in an organ bath. The contractions of the preparation were recorded through isometric transducers. The effects of the hormones on K(+) current and L-type Ca(2+) current (LTCC) were analyzed by using the whole cell voltage-clamp technique in A7r5 cells. RESULTS: Both ßES and PRG (1-100 µmol/L) concentration-dependently relaxed the endothelium-denuded aortic rings contracted by (-)-Bay K8644 (0.1 µmol/L) or by KCl (60 mmol/L). The IC(50) values of the two hormones were not statistically different. The K(V) channel blocker 4-aminopyridine (2 mmol/L), BK(Ca) channel blocker tetraethylammonium (1 mmol/L) and K(ATP) channel blocker glibenclamide (10 µmol/L) did not significantly modify the relaxant effect of the hormones. On the other hand, the blockage of the intracellular ßES and PRG receptors with estradiol receptor antagonists ICI 182,780 (1 µmol/L) and PRG receptor antagonist mifepristone (30 µmol/L), respectively, did not significantly modify the relaxant action of the hormones. In A7r5 cells, both the hormones (1-100 µmol/L) rapidly and reversibly inhibited the basal and BAY-stimulated LTCC. However, these hormones had no effect on the basal K(+) current. CONCLUSION: The vasorelaxant effects of ßES and PRG are due to the inhibition of LTCC. The K(+) channels are not involved in the effects.

Physical activity and determinants of sedentary behavior in Brazilian adolescents from an underdeveloped region.

The purpose of the study was to analyze the physical activity and the determinants of sedentary behavior in 1,268 Brazilian adolescents (638 girls, 630 boys) between the ages of 15 and 18 years, randomly selected from a relatively underdeveloped region. Data were collected from a community-based survey in the city of João Pessoa, Paraiba, Brazil. Information related to physical activity was derived on the short version of the International Physical Activity Questionnaire. The prevalence of sedentary behavior was 28.2% for girls and 19.1% for boys, whilst 28.9% of the girls and 36.7% of the boys showed high physical activity. The sedentary behavior varied by sociodemographic and environmental determinants studied. Parents' education, socioeconomic status, school's characteristics, transport to school, paid work, smoking, alcohol use, and BMI scores were significantly related to sedentary behavior for boys and girls.

Integrating physical and tactical factors in football using positional data: a systematic review.

Background: Positional data have been used to capture physical and tactical factors in football, however current research is now looking to apply spatiotemporal parameters from an integrative perspective. Thus, the aim of this article was to systematically review the published articles that integrate physical and tactical variables in football using positional data. Methods and Materials: Following the Preferred Reporting Item for Systematic Reviews and Meta-analyses (PRISMA), a systematic search of relevant English-language articles was performed from earliest record to August 2021. The methodological quality of the studies was evaluated using the modified Downs and Black Quality Index (observational and cross-sectional studies) and the Physiotherapy Evidence Database (PEDro) scale (intervention studies). Results: The literature search returned 982 articles (WoS = 495; PubMed = 232 and SportDiscus = 255). After screening, 26 full-text articles met the inclusion criteria and data extraction was conducted. All studies considered the integration of physical and tactical variables in football using positional data (n = 26). Other dimensions were also reported, such as psychophysiological and technical factors, however the results of these approaches were not the focus of the analysis (n = 5). Quasi-experimental approaches considered training sets (n = 20) and match contexts (n = 6). One study analysed both training and play insights. Small sided-games (SSG) were the most common training task formats in the reviewed studies, with only three articles addressing medium-sided (MSG) (n = 1) and large-sided games (LSG) (n = 2), respectively. Conclusions: Among the current systematic review, the physical data can be integrated by player's movement speed. Positional datasets can be computed by spatial movement, complex indexes, playing areas, intra-team and inter-team dyads. Futures researches should consider applying positional data in women's football environments and explore the representativeness of the MSG and LSG.

Effects of social and environmental determinants on overweight and obesity among Brazilian schoolchildren from a developing region.

OBJECTIVE: To identify the social and environmental determinants most strongly associated with overweight and obesity in Brazilian schoolchildren from a developing region. METHODS: Data were collected from a community-based survey of schoolchildren from the Valley of Jequitinhonha, Minas Gerais, Brazil. The sample was composed of 5 100 school children aged 6-18 years. Overweight and obesity were defined by body mass index based on the current method recommended by the World Health Organization in 2007. Social and environmental determinants were collected by using a structured questionnaire. RESULTS: The prevalence of overweight and obesity was 11.1% and 2.7% in girls and 8.2% and 1.5% in boys, respectively. The chance of overweight was higher in schoolchildren who engaged in remunerated work (odds ratio [OR] = 2.19, 95% confidence interval [CI] 1.30- 3.26), whose parents had higher education levels (OR = 1.52, 95% CI 1.12-2.07), who had two or fewer siblings (OR = 1.74, 95% CI 1.21-2.49), and who were in a high economic class (OR = 1.93, 95% CI 1.32-2.85). Schoolchildren who traveled by car to school (OR = 1.50, 95% CI 1.14-1.91), lived < 5 km from school (OR = 1.64, 95% CI 1.06-2.39), and consumed foods sold in the school cafeteria (OR = 1.56, 95% CI 1.19-2.16) presented high odds of being overweight. CONCLUSIONS: The background from a particular region of a country should be considered when implementing preventive measures regarding overweight and obesity, especially for very poor, developing regions like the Valley of Jequitinhonha. Measures taken should consider a multilevel intervention that includes the family, school, and physical environment.

Numerical simulations of a swimmer's head and cap wearing different types of goggles.

The aim of this study was to analyse the effect of swimming goggles on swimming hydrodynamics by numerical simulations. An elite swimmer volunteered for this research. The swimmer's head was scanned both without goggles, and while wearing 3 different types of goggles (Nikko, Ankor and Swedish). Numerical simulations were conducted at 2 m/s with the Fluent code. The condition without goggles showed the highest viscous drag (1.65 N), followed by the Ankor (1.64 N), Swedish (1.63 N) and Nikko (1.62 N) goggles, respectively. The highest pressure drag was found in the situation without goggles (11.34 N), followed by the Ankor (10.87 N), Nikko (10.78 N) and Swedish (10.20 N) goggles. The condition without goggles presented the highest total drag (12.99 N), followed by the Ankor (12.52 N), Nikko (12.40 N) and Swedish (11.83 N) goggles. Thus, Swedish goggles yields the best hydrodynamics, followed by the Nikko and Ankor goggles and lastly without goggles. Thus, goggles minimise the swimmer's drag comparing to not wearing any. The design of the goggles may impose varying drag forces and therefore it is advised to use goggles at least in competition.

Molecular and cellular basis of hyperassembly and protein aggregation driven by a rare pathogenic mutation in DDX3X.

Current studies estimate that 1-3% of females with unexplained intellectual disability (ID) present de novo splice site, nonsense, frameshift, or missense mutations in the DDX3X protein (DEAD-Box Helicase 3 X-Linked). However, the cellular and molecular mechanisms by which DDX3X mutations impair brain development are not fully comprehended. Here, we show that the ID-linked missense mutation L556S renders DDX3X prone to aggregation. By using a combination of biophysical assays and imaging approaches, we demonstrate that this mutant assembles solid-like condensates and amyloid-like fibrils. Although we observed greatly reduced expression of the mutant allele in a patient who exhibits skewed X inactivation, this appears to be enough to sequestrate healthy proteins into solid-like ectopic granules, compromising cell function. Therefore, our data suggest ID-linked DDX3X L556S mutation as a disorder arising from protein misfolding and aggregation.

Examining the accumulated oxygen deficit method in breaststroke swimming.

The present study investigated the accumulated oxygen deficit (AOD) method in breaststroke swimming with the aims to assess the reliability of the oxygen uptake/swimming velocity regression line and to quantify the precision of the AOD. Sixteen male swimmers performed two swimming tests in different days, with a 24-h recovery between tests: a graded swimming test and an all-out test. The all-out test was performed in one of two distances: 100 m (n = 7) or 200 m (n = 9). Through all testing, expired gases were collected breath by breath and analysed with a K4b2 Gas Analyser (Cosmed, Rome, Italy) connected to an AquaTrainer Valve (Cosmed, Rome, Italy). The standard error of the regression lines was approximately 5-6 ml kg(-1) min(-1) and the regressions allowed an extrapolation of the energy cost to higher intensities with a standard error of the predicted value that was lower in the 200-m bout (approximately 3.5 ml kg(-1) min(-1)) comparatively to the 100-m bout (approximately 6 ml kg(-1) min(-1)). The AOD imprecision was calculated as the square root of the sum of the oxygen uptake measurement error and the standard error of the predicted value for energy cost. AOD imprecision was smaller in the 200-m bout (approximately 9 ml kg(-1) min(-1)) comparatively to the 100-m bout (approximately 12 ml kg(-1) min(-1)). However, since the AOD values during the two distances were small, the AOD relative errors can be viewed as high. Additionally, the data variability was considerable (95% confidence intervals of the linear extrapolation larger than 20 ml kg(-1) min(-1)).

Kinematical changes in swimming front Crawl and Breaststroke with the AquaTrainer snorkel.

The aim of the present study was to assess the kinematical changes when swimming maximal bouts in Front Crawl and Breaststroke with the AquaTrainer snorkel. Thirteen male swimmers (7 at Breaststroke and 6 at Front Crawl) of national level performed randomly two maximal bouts of 100-m swims: one bout using the AquaTrainer snorkel (snorkel swim) and another one without the snorkel (free swim). The swims were videotaped in sagittal plane with a pair of cameras providing 2D kinematics evaluation. The following measures were assessed: swimming performance (T100), stroke cycle period (P), stroke rate (SR), stroke length (SL), swimming velocity (v), swimming efficiency as estimated by the stroke index (SI), speed fluctuation (dv) and the mathematical characterisation of dv. T100 was significantly higher when swimming with the snorkel than in free swimming at Breaststroke (Delta = 6.26%) and at Front Crawl (Delta = 4.75%). P, SR and SL, as well as SI and dv did not present significant differences. The main finding of the study was that changes in the swimming velocity imposed by the use of the Aquatrainer do not seem due to changes in general kinematics or swimming efficiency.

Physical growth of schoolchildren from the Jequitinhonha Valley, Minas Gerais, Brazil: Comparison with the CDC-2000 reference using the LMS method.

OBJECTIVE: To analyse the physical growth of a representative school population sample from the Jequitinhonha Valley, Minas Gerais, Brazil, in comparison with the reference proposed by the Centre for Disease Control and Prevention (CDC-2000). METHODS: The sample was composed of 5100 individuals (2730 girls and 2370 boys), aged 6-18 years. Body weight-for-age and height-for-age percentiles were obtained using the LMS method. Statistical and graphical comparisons were made with the corresponding percentiles of the CDC-2000 reference, estimated using the same method. RESULTS: Overall, the calculated values of the L (asymmetry) and the S (variability) parameters were quite similar to the CDC-2000 reference values. However, M (median) was substantially different from the reference used in the study, mainly in schoolchildren over 12-13 years of age of both genders. The magnitude of the deficits of height-for-age and body weight-for-age observed in the schoolchildren from the Jequitinhonha Valley, Minas Gerais, Brazil, varied from 4 to 6 cm and from 3 to 6 kg, respectively. CONCLUSION: The body weight-for-age and height-for-age percentiles of schoolchildren population in the Jequitinhonha Valley, Minas Gerais, Brazil differed substantially from those referenced.

Effect of seasonal variations on fatty acid composition and nutritional profiles of siluriformes fish species from the amazon basin.

Siluriformes is a highly diverse order of species that exhibit a wide array of morphologies, diets and life strategies. This study evaluated the effect of seasonal variations on the proximate composition, fatty acid composition and nutritional profiles of nine fish species of Siluriformes order from the Amazon Basin. The proximate composition varied throughout seasonal periods with larger differences in total lipid content. Hypophthalmus edentaus showed the largest variation (9.26-26.29%) between drought and flood periods, respectively. The fatty acid composition also varied throughout seasonal periods; the polyunsaturated fatty acid (PUFA) contents significantly (p < 0.05) increased for most of the studied species in the flood period and n-3 fatty acids represented 23% of this increase. Docosahexaenoic acid was the most abundant PUFA during the flood period and Pseudoplatystoma tigrinum (40.17 mg g-1) and Pseudoplatystoma fasciatum (39.93 mg g-1) showed the highest contents. Some species such as Ageneiosus inermis exceed the recommended daily intake of EPA + DHA. All the fish species presented favorable indices of nutritional quality for total lipids. The principal component analysis resulted in a two-principal component model that described 85.15% of the total data variance. It also highlighted that the nine fish species were affected by seasonal variations in their habitat, some to a greater extent than others. The results suggested that the consumption of those fish species contributed to human health.

The Effectiveness of a Dry-Land Shoulder Rotators Strength Training Program in Injury Prevention in Competitive Swimmers.

Competitive swimmers usually undergo large mileage of daily training, in which propulsive force is produced mainly by the upper limbs. Some studies claim that dry-land shoulder rotators injury prevention programs before the in-water swim practice are paramount. However, the effect of shoulder strengthening prior to water training is unclear. This study aimed to analyse the acute effects of training programs conducted on dry land with the goal of preventing shoulder rotators injuries. A group of young swimmers (N = 23) was recruited to participate in this research. The peak torques of shoulder internal and external rotators were assessed before and after the completion of the compensatory strength training program. The isokinetic assessment was performed using two different protocols: 3 repetitions at 60⍛/s and 20 repetitions at 180⍛/s. Except for a trivial reduction in strength after the training program, there were no other significant differences in any of the studied variables (shoulders rotators endurance, strength and muscle balance). All results showed trivial to small effect sizes. Our findings suggest that a compensatory strength training program does not have a significant acute effect on the strength, endurance and muscle balance of shoulder rotators in young swimmers.

Association between ACE D allele and elite short distance swimming.

The influence of ACE gene on athletic performance has been widely explored, and most of the published data refers to an I/D polymorphism leading to the presence (I allele) or absence (D allele) of a 287-bp sequence in intron 16, determining ACE activity in serum and tissues. A higher I allele frequency has been reported among elite endurance athletes, while the D allele was more frequent among those engaged in more power-orientated sports. However, on competitive swimming, the reproducibility of such associations is controversial. We thus compared the ACE genotype of elite swimmers with that of non-elite swimming cohort and of healthy control subjects. We thus sought an association of the ACE genotype of elite swimmers with their competitive distance. 39 Portuguese Olympic swimming candidates were classified as: short (<200 m) and middle (400-1,500 m) distance swimmers, respectively. A group of 32 non-elite swimmers were studied and classified as well, and a control group (n = 100) was selected from the Portuguese population. Chelex 100 was used for DNA extraction and genotype was determined by PCR-RFLP methods. We found that ACE genotype distribution and allelic frequency differs significantly by event distance only among elite swimmers (P < or = 0.05). Moreover, the allelic frequency of the elite short distance swimmers differed significantly from that of the controls (P = 0.021). No associations were found between middle distance swimmers and controls. Our results seem to support an association between the D allele and elite short distance swimming.

Accuracy, reliability, linearity of Accutrend and Lactate Pro versus EBIO plus analyzer.

The accuracy, reliability and linearity in two hand-portable lactate analyzers, the Accutrend Lactate (AL) and the Lactate Pro (LP) versus the EBIO plus analyzer (EP) were evaluated. For accuracy, duplicate samples recorded on both the AL and LP revealed an overall average difference versus EP (P < 0.05). The limits of agreement between AL and EP were -0.7 to +1.0, and -1.3 to +1.5 mM between LP and EP. Reliability of AL and LP was assessed at different lactate concentrations; coefficient of variation ranged between 1.8 and 3.3% for AL and between 2.8 and 5.0% for LP. AL and LP had a good reliability for intra-, inter-analyzers, and between test strips (ICC r = 0.999). The linearity was determined versus the EP as reference. The slope coefficient of AL (1.0394) was closer to 1 than that of LP (1.1053). On these bases, AL and LP can be individually considered suitable for the sports research field.

Angiotensin-converting enzyme genotype affects skeletal muscle strength in elite athletes.

Previous studies have associated angiotensin-converting enzyme (ACE) D allele with variability in the skeletal muscle baseline strength, though conclusions have been inconsistent across investigations. The purpose of this study was to examine the possible association between ACE genotype and skeletal muscle baseline strength in elite male and female athletes involved in different event expertise. A group of 58 elite athletes, designated as Olympic candidates, were studied: 35 swimmers (19 males and 16 females, 18.8 ± 3.2 years) and 23 triathletes (15 males and 8 females, 18.7 ± 3.0 years). The athletes were classified as: short (≤ 200m) and middle (400m to 1500m) distance athletes, respectively. For each subject the grip strength in both hands was measure using an adjustable mechanical hand dynamometer. The maximum height in both squat jump (SJ) and counter movement jump (CMJ) were also assessed, using a trigonometric carpet (Ergojump Digitime 1000; Digitest, Jyvaskyla, Finland). DNA extraction was obtained with Chelex 100(®) and genotype determination by PCR-RFLP methods. Both males and females showed significantly higher right grip strength in D allele carriers compared to II homozygote's. We found that allelic frequency differs significantly by event distance specialization in both genders (p < 0.05). In fact, sprinter D allele carriers showed the superior scores in nearly all strength measurements (p < 0.05), in both genders. Among endurance athletes, the results also demonstrated that female D allele carriers exhibited the higher performance right grip and CMJ scores (p < 0.05). In conclusion, the ACE D allele seems associated with skeletal muscle baseline strength in elite athletes, being easily identified in females. Key pointsDD homozygote's and D allele carriers from both genders shows significantly higher right grip strength.Right grip strength remains significantly higher in the D allele carrier's female endurance group.Female's D allele carriers exhibited the higher performance counter-movement jump scores.ACE genotype effects in skeletal-muscle strength are diverse by gender, being easily identified in females.

Behavioral, contextual and biological factors associated with obesity during adolescence: A systematic review.

INTRODUCTION/OBJECTIVE: Adolescence is a critical period for the development of obesity. Obesity arises from a complex interaction between several factors, which are not yet fully understood. Therefore, the purpose of this review was to identify and assess the peer-reviewed scientific literature on the behavioral, contextual and biological factors associated with obesity in adolescents. METHODS: PubMed and Scopus were systematically searched to identify prospective cohort studies concerning the relation between behavioral, contextual and biological factors and obesity in adolescents aged 10 to 18 years. RESULTS: 40 studies published between the year 2000 and 2018 were included. A positive consistent association between genetic factors and obesity during adolescence was found. Also, there is evidence to support the association between socioeconomic status and obesity. There was conflicting evidence for the contribution of dietary intake, physical activity, sedentary behavior, sleep, food store environment, school food environment. For the remaining factors no associations were found, or no conclusions could be drawn due to the limited number of studies identified. CONCLUSIONS: Further prospective studies that assess multiple obesity determinants simultaneously and use state-of-art measures are warranted to aid in the development of effective strategies and interventions to prevent obesity during adolescence.