Detalhe da pesquisa
1.
Structural basis of omega-3 fatty acid transport across the blood-brain barrier.
Nature
; 595(7866): 315-319, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34135507
2.
Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport.
Proc Natl Acad Sci U S A
; 120(10): e2215290120, 2023 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36848557
3.
Destabilization of ß Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes.
Proc Natl Acad Sci U S A
; 119(11): e2113074119, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35254894
4.
Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage.
Proc Natl Acad Sci U S A
; 119(40): e2210353119, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36161949
5.
Mfsd2a-mediated lysolipid transport is important for renal recovery after acute kidney injury.
J Lipid Res
; 64(8): 100416, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37467896
6.
The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis.
J Biol Chem
; 298(3): 101709, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35150739
7.
Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss.
Circ Res
; 128(4): e46-e62, 2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375813
8.
Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets.
Nature
; 550(7677): 524-528, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045386
9.
Application of Neuron-Selective Fluorescent Probe, NeuA, To Identify Mouse Retinal Degeneration.
Chembiochem
; 22(11): 1915-1919, 2021 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33617145
10.
The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain.
PLoS Biol
; 16(8): e2006443, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30074985
11.
The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection.
J Immunol
; 203(1): 117-126, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127034
12.
Fat storage-inducing transmembrane protein 2 (FIT2) is less abundant in type 2 diabetes, and regulates triglyceride accumulation and insulin sensitivity in adipocytes.
FASEB J
; 33(1): 430-440, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30020828
13.
Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid.
Nature
; 509(7501): 503-6, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24828044
14.
Mfsd2a: A Physiologically Important Lysolipid Transporter in the Brain and Eye.
Adv Exp Med Biol
; 1276: 223-234, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32705603
15.
Homozygous mutation in MFSD2A, encoding a lysolipid transporter for docosahexanoic acid, is associated with microcephaly and hypomyelination.
Neurogenetics
; 19(4): 227-235, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30043326
16.
A mutation of EPT1 (SELENOI) underlies a new disorder of Kennedy pathway phospholipid biosynthesis.
Brain
; 140(3): 547-554, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28052917
17.
Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A.
J Biol Chem
; 291(18): 9383-94, 2016 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26945070
18.
Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development.
J Biol Chem
; 291(20): 10501-14, 2016 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27008858
19.
Cytosolic lipid droplets: from mechanisms of fat storage to disease.
Crit Rev Biochem Mol Biol
; 49(4): 304-26, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25039762
20.
Postnatal Deletion of Fat Storage-inducing Transmembrane Protein 2 (FIT2/FITM2) Causes Lethal Enteropathy.
J Biol Chem
; 290(42): 25686-99, 2015 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26304121