Detalhe da pesquisa
1.
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling.
Proc Natl Acad Sci U S A
; 121(15): e2320194121, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38568967
2.
ASCC1 structures and bioinformatics reveal a novel Helix-Clasp-Helix RNA-binding motif linked to a two-histidine phosphodiesterase.
J Biol Chem
; : 107368, 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38750793
3.
H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer.
Proc Natl Acad Sci U S A
; 119(21): e2114324119, 2022 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35584120
4.
Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death.
EMBO J
; 39(11): e101573, 2020 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32323871
5.
Zika virus employs the host antiviral RNase L protein to support replication factory assembly.
Proc Natl Acad Sci U S A
; 118(22)2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031250
6.
SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes.
Proc Natl Acad Sci U S A
; 118(16)2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33811184
7.
A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
Proc Natl Acad Sci U S A
; 117(40): 24802-24812, 2020 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32958664
8.
Ablation of SigH+ pDCs in B6.Nba2 mice prevents lupus-like disease development only if started before disease is fully established.
Lupus
; 31(13): 1619-1629, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36134524
9.
Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol Cell
; 53(2): 221-34, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24462203
10.
OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug.
Proc Natl Acad Sci U S A
; 116(11): 5071-5076, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30814222
11.
Reverse Genetics Reveals a Role of Rotavirus VP3 Phosphodiesterase Activity in Inhibiting RNase L Signaling and Contributing to Intestinal Viral Replication In Vivo.
J Virol
; 94(9)2020 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32051268
12.
Zika Virus Production Is Resistant to RNase L Antiviral Activity.
J Virol
; 93(16)2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31142667
13.
A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.
PLoS Pathog
; 14(4): e1006989, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29652922
14.
Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death.
EMBO J
; 39(20): e106593, 2020 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33058249
15.
Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication.
PLoS Pathog
; 13(2): e1006195, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28158275
16.
Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses.
Proc Natl Acad Sci U S A
; 113(8): 2241-6, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26858407
17.
Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L.
J Virol
; 91(5)2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003490
18.
Activation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on Basal Oas Gene Expression and Independent of Virus-Induced Interferon.
J Virol
; 90(6): 3160-72, 2016 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26739051
19.
Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activation.
J Gen Virol
; 97(4): 880-886, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26757803
20.
RNase L targets distinct sites in influenza A virus RNAs.
J Virol
; 89(5): 2764-76, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25540362