Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Temporal dynamics and genomic programming of plasma cell fates.

Manakkat Vijay, Godhev Kumar; Zhou, Ming; Thakkar, Kairavee; Rothrauff, Abigail; Chawla, Amanpreet Singh; Chen, Dianyu; Lau, Louis Chi-Wai; Gerges, Peter Habib; Chetal, Kashish; Chhibbar, Prabal; Fan, Jingyu; Das, Jishnu; Joglekar, Alok; Borghesi, Lisa; Salomonis, Nathan; Xu, Heping; Singh, Harinder.

Nat Immunol ; 2024 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-38698087

2.

An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors.

Zhang, Xuan; Song, Baobao; Carlino, Maximillian J; Li, Guangyuan; Ferchen, Kyle; Chen, Mi; Thompson, Evrett N; Kain, Bailee N; Schnell, Dan; Thakkar, Kairavee; Kouril, Michal; Jin, Kang; Hay, Stuart B; Sen, Sidharth; Bernardicius, David; Ma, Siyuan; Bennett, Sierra N; Croteau, Josh; Salvatori, Ornella; Lye, Melvin H; Gillen, Austin E; Jordan, Craig T; Singh, Harinder; Krause, Diane S; Salomonis, Nathan; Grimes, H Leighton.

Nat Immunol ; 25(4): 703-715, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38514887

3.

Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis.

Zhang, Shiqun; Edwards, Tara N; Chaudhri, Virendra K; Wu, Jianing; Cohen, Jonathan A; Hirai, Toshiro; Rittenhouse, Natalie; Schmitz, Elizabeth G; Zhou, Paul Yifan; McNeil, Benjamin D; Yang, Yi; Koerber, H Richard; Sumpter, Tina L; Poholek, Amanda C; Davis, Brian M; Albers, Kathryn M; Singh, Harinder; Kaplan, Daniel H.

Cell ; 184(8): 2151-2166.e16, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33765440

4.

Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation.

Chen, Dianyu; Wang, Yan; Manakkat Vijay, Godhev K; Fu, Shujie; Nash, Colt W; Xu, Di; He, Danyang; Salomonis, Nathan; Singh, Harinder; Xu, Heping.

Nat Immunol ; 22(7): 904-913, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34031613

5.

Charting the cis-regulome of activated B cells by coupling structural and functional genomics.

Chaudhri, Virendra K; Dienger-Stambaugh, Krista; Wu, Zhiguo; Shrestha, Mahesh; Singh, Harinder.

Nat Immunol ; 21(2): 210-220, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31873292

6.

Competition for Active TGFß Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche.

Hirai, Toshiro; Yang, Yi; Zenke, Yukari; Li, Haiyue; Chaudhri, Virendra K; De La Cruz Diaz, Jacinto S; Zhou, Paul Yifan; Nguyen, Breanna Anh-Thu; Bartholin, Laurent; Workman, Creg J; Griggs, David W; Vignali, Dario A A; Singh, Harinder; Masopust, David; Kaplan, Daniel H.

Immunity ; 54(1): 84-98.e5, 2021 01 12.

Artigo em Inglês | MEDLINE | ID: mdl-33212014

7.

Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8.

Xu, Heping; Chaudhri, Virendra K; Wu, Zhiguo; Biliouris, Konstantinos; Dienger-Stambaugh, Krista; Rochman, Yrina; Singh, Harinder.

Nat Immunol ; 16(12): 1274-81, 2015 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-26437243

8.

DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina.

Zullo, Joseph M; Demarco, Ignacio A; Piqué-Regi, Roger; Gaffney, Daniel J; Epstein, Charles B; Spooner, Chauncey J; Luperchio, Teresa R; Bernstein, Bradley E; Pritchard, Jonathan K; Reddy, Karen L; Singh, Harinder.

Cell ; 149(7): 1474-87, 2012 Jun 22.

Artigo em Inglês | MEDLINE | ID: mdl-22726435

9.

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation.

Vander Lugt, Bryan; Khan, Aly A; Hackney, Jason A; Agrawal, Smita; Lesch, Justin; Zhou, Meijuan; Lee, Wyne P; Park, Summer; Xu, Min; DeVoss, Jason; Spooner, Chauncey J; Chalouni, Cecile; Delamarre, Lelia; Mellman, Ira; Singh, Harinder.

Nat Immunol ; 15(2): 161-7, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24362890

10.

Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1.

Spooner, Chauncey J; Lesch, Justin; Yan, Donghong; Khan, Aly A; Abbas, Alex; Ramirez-Carrozzi, Vladimir; Zhou, Meijuan; Soriano, Robert; Eastham-Anderson, Jeffrey; Diehl, Lauri; Lee, Wyne P; Modrusan, Zora; Pappu, Rajita; Xu, Min; DeVoss, Jason; Singh, Harinder.

Nat Immunol ; 14(12): 1229-36, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24141388

11.

Author Correction: Single-cell analysis of mixed-lineage states leading to a binary cell fate choice.

Olsson, Andre; Venkatasubramanian, Meenakshi; Chaudhri, Virendra K; Aronow, Bruce J; Salomonis, Nathan; Singh, Harinder; Grimes, H Leighton.

Nature ; 569(7755): E3, 2019 May.

Artigo em Inglês | MEDLINE | ID: mdl-31019298

12.

Cell fate dynamics and genomic programming of plasma cell precursors.

Manakkat Vijay, Godhev K; Singh, Harinder.

Immunol Rev ; 303(1): 62-71, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34195999

13.

Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling.

Seiler, Michael P; Mathew, Rebecca; Liszewski, Megan K; Spooner, Chauncey J; Spooner, Chauncey; Barr, Kenneth; Meng, Fanyong; Singh, Harinder; Bendelac, Albert.

Nat Immunol ; 13(3): 264-71, 2012 Feb 05.

Artigo em Inglês | MEDLINE | ID: mdl-22306690

14.

A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.

Ochiai, Kyoko; Maienschein-Cline, Mark; Mandal, Malay; Triggs, Joseph R; Bertolino, Eric; Sciammas, Roger; Dinner, Aaron R; Clark, Marcus R; Singh, Harinder.

Nat Immunol ; 13(3): 300-7, 2012 Jan 22.

Artigo em Inglês | MEDLINE | ID: mdl-22267219

15.

A cross-institutional analysis of the effects of broadening trainee professional development on research productivity.

Brandt, Patrick D; Sturzenegger Varvayanis, Susi; Baas, Tracey; Bolgioni, Amanda F; Alder, Janet; Petrie, Kimberly A; Dominguez, Isabel; Brown, Abigail M; Stayart, C Abigail; Singh, Harinder; Van Wart, Audra; Chow, Christine S; Mathur, Ambika; Schreiber, Barbara M; Fruman, David A; Bowden, Brent; Wiesen, Christopher A; Golightly, Yvonne M; Holmquist, Chris E; Arneman, Daniel; Hall, Joshua D; Hyman, Linda E; Gould, Kathleen L; Chalkley, Roger; Brennwald, Patrick J; Layton, Rebekah L.

PLoS Biol ; 19(7): e3000956, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34264929

16.

Teeing up transcription on CpG islands.

Singh, Harinder.

Cell ; 138(1): 14-6, 2009 Jul 10.

Artigo em Inglês | MEDLINE | ID: mdl-19596228

17.

Transcription factor c-Maf mediates the TGF-ß-dependent suppression of IL-22 production in T(H)17 cells.

Rutz, Sascha; Noubade, Rajkumar; Eidenschenk, Céline; Ota, Naruhisa; Zeng, Wenwen; Zheng, Yan; Hackney, Jason; Ding, Jiabing; Singh, Harinder; Ouyang, Wenjun.

Nat Immunol ; 12(12): 1238-45, 2011 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-22001828

18.

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.

Ramirez-Carrozzi, Vladimir; Sambandam, Arivazhagan; Luis, Elizabeth; Lin, Zhongua; Jeet, Surinder; Lesch, Justin; Hackney, Jason; Kim, Janice; Zhou, Meijuan; Lai, Joyce; Modrusan, Zora; Sai, Tao; Lee, Wyne; Xu, Min; Caplazi, Patrick; Diehl, Lauri; de Voss, Jason; Balazs, Mercedesz; Gonzalez, Lino; Singh, Harinder; Ouyang, Wenjun; Pappu, Rajita.

Nat Immunol ; 12(12): 1159-66, 2011 Oct 12.

Artigo em Inglês | MEDLINE | ID: mdl-21993848

19.

COVID-19db linkage maps of cell surface proteins and transcription factors in immune cells.

Ramjattun, Koushul; Ma, Xiaojun; Gao, Shou-Jiang; Singh, Harinder; Osmanbeyoglu, Hatice Ulku.

J Med Virol ; 95(6): e28887, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37341527

20.

Translational implications of humoral and cellular immune dysfunction in granulomatosis with polyangiitis.

Singh, Harinder; Kumar, Uma; Senapati, Sabyasachi.

Cytokine ; 164: 156154, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36812668

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