Detalhe da pesquisa
1.
Microglia-specific knock-out of NF-κB/IKK2 increases the accumulation of misfolded α-synuclein through the inhibition of p62/sequestosome-1-dependent autophagy in the rotenone model of Parkinson's disease.
Glia
; 71(9): 2154-2179, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37199240
2.
Rotenone induces regionally distinct α-synuclein protein aggregation and activation of glia prior to loss of dopaminergic neurons in C57Bl/6 mice.
Neurobiol Dis
; 167: 105685, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35257879
3.
COVID-19 Infection Enhances Susceptibility to Oxidative Stress-Induced Parkinsonism.
Mov Disord
; 37(7): 1394-1404, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35579496
4.
Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity.
Nat Immunol
; 9(6): 658-66, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18469818
5.
Exogenous activation of tumor necrosis factor receptor 2 promotes recovery from sensory and motor disease in a model of multiple sclerosis.
Brain Behav Immun
; 81: 247-259, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31220564
6.
Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo.
Brain
; 141(6): 1753-1769, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29800472
7.
SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus.
J Neurosci
; 35(29): 10510-22, 2015 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26203146
8.
p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1.
J Biol Chem
; 289(45): 31458-72, 2014 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25253694
9.
GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults.
NPJ Parkinsons Dis
; 10(1): 83, 2024 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38615030
10.
Normal midbrain dopaminergic neuron development and function in miR-133b mutant mice.
J Neurosci
; 32(32): 10887-94, 2012 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22875923
11.
Inflammatory effects of highly pathogenic H5N1 influenza virus infection in the CNS of mice.
J Neurosci
; 32(5): 1545-59, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22302798
12.
Neuroanatomical and neurochemical effects of prolonged social isolation in adult mice.
Front Neuroanat
; 17: 1190291, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37662476
13.
GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults.
Res Sq
; 2023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37886524
14.
Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes.
Hum Mol Genet
; 19(9): 1633-50, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20106867
15.
Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells.
J Immunol
; 184(9): 4863-70, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20348424
16.
Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration.
Proc Natl Acad Sci U S A
; 106(33): 14063-8, 2009 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19667183
17.
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte.
Proc Natl Acad Sci U S A
; 106(8): 2933-8, 2009 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19196989
18.
Mutant LRRK2 in lymphocytes regulates neurodegeneration via IL-6 in an inflammatory model of Parkinson's disease.
NPJ Parkinsons Dis
; 8(1): 24, 2022 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35292674
19.
Alzheimer's disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment.
Nat Aging
; 2(10): 923-940, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36636325
20.
Infection and Risk of Parkinson's Disease.
J Parkinsons Dis
; 11(1): 31-43, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33361610