Detalhe da pesquisa
1.
In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity.
Drug Metab Dispos
; 44(10): 1682-91, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27504016
2.
Stable isotope-labelled intravenous microdose for absolute bioavailability and effect of grapefruit juice on ibrutinib in healthy adults.
Br J Clin Pharmacol
; 81(2): 235-45, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26382728
3.
Combination of ibrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) for treatment-naive patients with CD20-positive B-cell non-Hodgkin lymphoma: a non-randomised, phase 1b study.
Lancet Oncol
; 15(9): 1019-26, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25042202
4.
Comparative pharmacokinetics and bioavailability of tapentadol following oral administration of immediate- and prolonged-release formulations.
Int J Clin Pharmacol Ther
; 51(4): 338-48, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23357834
5.
Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism.
J Clin Invest
; 117(11): 3583-92, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17975676
6.
Predicting oral clearance in humans: how close can we get with allometry?
Clin Pharmacokinet
; 47(1): 35-45, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18076217
7.
Phase 1b Study of Abiraterone Acetate Plus Prednisone and Docetaxel in Patients with Metastatic Castration-resistant Prostate Cancer.
Eur Urol
; 70(5): 718-721, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26852075
8.
Phase I Dose-Escalation Study of JNJ-42756493, an Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients With Advanced Solid Tumors.
J Clin Oncol
; 33(30): 3401-8, 2015 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26324363
9.
Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs.
AIDS
; 16(17): 2295-301, 2002 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-12441801
10.
Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency.
J Clin Endocrinol Metab
; 99(8): 2763-70, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24780050
11.
Pharmacokinetic evaluation of tapentadol extended-release tablets in healthy subjects.
J Opioid Manag
; 9(4): 291-300, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24353023
12.
A phase I study of quisinostat (JNJ-26481585), an oral hydroxamate histone deacetylase inhibitor with evidence of target modulation and antitumor activity, in patients with advanced solid tumors.
Clin Cancer Res
; 19(15): 4262-72, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23741066
13.
Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects.
Pain
; 153(8): 1648-1656, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22703892
14.
Towards a better prediction of peak concentration, volume of distribution and half-life after oral drug administration in man, using allometry.
Clin Pharmacokinet
; 50(5): 307-18, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21456631
15.
Population pharmacokinetics of tapentadol immediate release (IR) in healthy subjects and patients with moderate or severe pain.
Clin Pharmacokinet
; 49(10): 671-82, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20818833
16.
Effects of acetaminophen, naproxen, and acetylsalicylic acid on tapentadol pharmacokinetics: results of two randomized, open-label, crossover, drug-drug interaction studies.
Pharmacotherapy
; 30(1): 25-34, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20030470
17.
Midazolam and cyclosporin a metabolism in transgenic mice with liver-specific expression of human CYP3A4.
Drug Metab Dispos
; 33(7): 892-5, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15845749
18.
Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir.
J Pharmacol Exp Ther
; 304(2): 596-602, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12538811