Detalhe da pesquisa
1.
The PqsE and RhlR proteins are an autoinducer synthase-receptor pair that control virulence and biofilm development in Pseudomonas aeruginosa.
Proc Natl Acad Sci U S A
; 115(40): E9411-E9418, 2018 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30224496
2.
The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer.
PLoS Pathog
; 13(7): e1006504, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28715477
3.
Flavonoids Suppress Pseudomonas aeruginosa Virulence through Allosteric Inhibition of Quorum-sensing Receptors.
J Biol Chem
; 292(10): 4064-4076, 2017 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28119451
4.
Selective sodium-dependent glucose transporter 1 inhibitors block glucose absorption and impair glucose-dependent insulinotropic peptide release.
Am J Physiol Gastrointest Liver Physiol
; 308(11): G946-54, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25767259
5.
Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production.
ACS Chem Biol
; 16(4): 740-752, 2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33793200
6.
Discovery of PqsE Thioesterase Inhibitors for Pseudomonas aeruginosa Using DNA-Encoded Small Molecule Library Screening.
ACS Chem Biol
; 15(2): 446-456, 2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31880429
7.
PPARgamma agonists inhibit vasopressin-mediated anion transport in the MDCK-C7 cell line.
Am J Physiol Renal Physiol
; 297(1): F55-62, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19403648
8.
An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
ACS Chem Biol
; 14(3): 378-389, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30763066
9.
Inhibitor binding in the human renal low- and high-affinity Na+/glucose cotransporters.
J Pharmacol Exp Ther
; 324(3): 985-91, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18063724
10.
Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes.
Diabetes
; 54(12): 3427-34, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16306358
11.
Development of a novel high-throughput surrogate assay to measure HIV envelope/CCR5/CD4-mediated viral/cell fusion using BacMam baculovirus technology.
J Biomol Screen
; 8(4): 463-70, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-14567799
12.
Synthesis and SAR of Benzisothiazole- and Indolizine-ß-d-glucopyranoside Inhibitors of SGLT2.
ACS Med Chem Lett
; 1(1): 19-23, 2010 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900169
13.
PPARgamma agonists do not directly enhance basal or insulin-stimulated Na(+) transport via the epithelial Na(+) channel.
Pflugers Arch
; 451(3): 445-53, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16170524
14.
Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94.
J Lipid Res
; 43(8): 1320-30, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12177176