Detalhe da pesquisa
1.
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel.
Nature
; 469(7330): 428-31, 2011 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21248852
2.
Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family.
Proc Natl Acad Sci U S A
; 108(29): 12143-8, 2011 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21730130
3.
3-Hydroxybutyric acid interacts with lipid monolayers at concentrations that impair consciousness.
Langmuir
; 29(6): 1948-55, 2013 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23339286
4.
Conserved role of unc-79 in ethanol responses in lightweight mutant mice.
PLoS Genet
; 6(8)2010 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20714347
5.
Gamma-aminobutyric acid type A receptor ß3 subunit forebrain-specific knockout mice are resistant to the amnestic effect of isoflurane.
Anesth Analg
; 113(3): 500-4, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21813630
6.
Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel.
Anesth Analg
; 110(1): 59-63, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19933531
7.
Tolerance to isoflurane does not occur in developing Xenopus laevis tadpoles.
Anesth Analg
; 108(1): 176-80, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19095846
8.
Isovaleric, methylmalonic, and propionic acid decrease anesthetic EC50 in tadpoles, modulate glycine receptor function, and interact with the lipid 1,2-dipalmitoyl-Sn-glycero-3-phosphocholine.
Anesth Analg
; 108(5): 1538-45, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19372333
9.
Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isoflurane.
Anesth Analg
; 109(6): 1816-22, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19923508
10.
Knockout of the gene encoding the K(2P) channel KCNK7 does not alter volatile anesthetic sensitivity.
Behav Brain Res
; 193(2): 192-6, 2008 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-18572259
11.
A hypothesis on the origin and evolution of the response to inhaled anesthetics.
Anesth Analg
; 107(3): 849-54, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18713893
12.
The anesthetic-like effects of diverse compounds on wild-type and mutant gamma-aminobutyric acid type A and glycine receptors.
Anesth Analg
; 106(3): 838-45, table of contents, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18292428
13.
Anesthetic-like modulation of receptor function by surfactants: a test of the interfacial theory of anesthesia.
Anesth Analg
; 107(3): 868-74, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18713898
14.
Is synergy the rule? A review of anesthetic interactions producing hypnosis and immobility.
Anesth Analg
; 107(2): 494-506, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18633028
15.
Is a new paradigm needed to explain how inhaled anesthetics produce immobility?
Anesth Analg
; 107(3): 832-48, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18713892
16.
Inhaled anesthetics do not combine to produce synergistic effects regarding minimum alveolar anesthetic concentration in rats.
Anesth Analg
; 107(2): 479-85, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18633026
17.
Anesthetic properties of carbon dioxide in the rat.
Anesth Analg
; 105(1): 103-6, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17578964
18.
Alterations in spinal, but not cerebral, cerebrospinal fluid Na+ concentrations affect the isoflurane minimum alveolar concentration in rats.
Anesth Analg
; 105(3): 661-5, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17717220
19.
Anesthetic properties of the ketone bodies beta-hydroxybutyric acid and acetone.
Anesth Analg
; 105(3): 673-9, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17717222
20.
Mouse chromosome 7 harbors a quantitative trait locus for isoflurane minimum alveolar concentration.
Anesth Analg
; 105(2): 381-5, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17646494