Detalhe da pesquisa
1.
SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D2 Receptor Mechanism of Action.
J Pharmacol Exp Ther
; 371(1): 1-14, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371483
2.
The evolution of library design: crafting smart compound collections for phenotypic screens.
Drug Discov Today Technol
; 23: 61-67, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28647087
3.
Pharmacodynamic effects of a D-amino acid oxidase inhibitor indicate a spinal site of action in rat models of neuropathic pain.
J Pharmacol Exp Ther
; 345(3): 502-11, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23520265
4.
Discovery of 1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydroquinolin-4-amine, a dual serotonin and dopamine reuptake inhibitor.
Bioorg Med Chem Lett
; 21(1): 520-3, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21095126
5.
Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor.
Bioorg Med Chem Lett
; 21(5): 1438-41, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21310609
6.
Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine reuptake inhibitor.
Bioorg Med Chem Lett
; 21(5): 1434-7, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21310612
7.
Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.
Bioorg Med Chem
; 19(1): 663-76, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21093273
8.
Aryl sulfonamido tetralin inhibitors of the Kv1.5 ion channel.
Bioorg Med Chem Lett
; 19(11): 3063-6, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19398199
9.
Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation.
Biosci Rep
; 34(4)2014 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25001371
10.
Effects of D-amino acid oxidase inhibition on memory performance and long-term potentiation in vivo.
Pharmacol Res Perspect
; 1(1): e00007, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505561
11.
Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules.
J Med Chem
; 56(9): 3710-24, 2013 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23631755
12.
Synthesis and pharmacological characterization of bicyclic triple reuptake inhibitor 3-aryl octahydrocyclopenta[c]pyrrole analogues.
J Med Chem
; 54(15): 5283-95, 2011 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21739935