Detalhe da pesquisa
1.
Differential resting-state patterns across networks are spatially associated with Comt and Trmt2a gene expression patterns in a mouse model of 22q11.2 deletion.
Neuroimage
; 243: 118520, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34455061
2.
Brexpiprazole II: antipsychotic-like and procognitive effects of a novel serotonin-dopamine activity modulator.
J Pharmacol Exp Ther
; 350(3): 605-14, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947464
3.
Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator.
J Pharmacol Exp Ther
; 350(3): 589-604, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947465
4.
Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis.
PLoS Med
; 9(10): e1001326, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23091423
5.
Differential effects of gamma-secretase and BACE1 inhibition on brain Abeta levels in vitro and in vivo.
J Neurochem
; 110(5): 1377-87, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19519664
6.
An acetylcholine alpha7 positive allosteric modulator rescues a schizophrenia-associated brain endophenotype in the 15q13.3 microdeletion, encompassing CHRNA7.
Eur Neuropsychopharmacol
; 26(7): 1150-60, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27061851
7.
Changes in KCNQ2 immunoreactivity in the amygdala in two rat models of temporal lobe epilepsy.
Brain Res Mol Brain Res
; 141(1): 66-73, 2005 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16154661
8.
The preclinical profile of brexpiprazole: what is its clinical relevance for the treatment of psychiatric disorders?
Expert Rev Neurother
; 15(10): 1219-29, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26402059
9.
The AMPA receptor binding site: focus on agonists and competitive antagonists.
Curr Pharm Des
; 8(10): 857-72, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-11945136
10.
Characterization of [³H]Lu AE60157 ([³H]8-(4-methylpiperazin-1-yl)-3-phenylsulfonylquinoline) binding to 5-hydroxytryptamine6 (5-HT6) receptors in vivo.
Eur J Pharmacol
; 676(1-3): 6-11, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22155399
11.
Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder.
J Med Chem
; 54(9): 3206-21, 2011 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21486038
12.
NEWMEDS special issue commentary.
Psychopharmacology (Berl)
; 232(21-22): 3849-51, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26407600
13.
Synthesis of enantiomerically pure milnacipran analogs and inhibition of dopamine, serotonin, and norepinephrine transporters.
Bioorg Med Chem Lett
; 17(10): 2834-7, 2007 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17350257
14.
Synthesis and preliminary biological evaluation of 2'-substituted 2-(3'-carboxybicyclo[1.1.1]pentyl)glycine derivatives as group I selective metabotropic glutamate receptor ligands.
ChemMedChem
; 1(3): 358-65, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16892370