Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells.

La Manno, Gioele; Gyllborg, Daniel; Codeluppi, Simone; Nishimura, Kaneyasu; Salto, Carmen; Zeisel, Amit; Borm, Lars E; Stott, Simon R W; Toledo, Enrique M; Villaescusa, J Carlos; Lönnerberg, Peter; Ryge, Jesper; Barker, Roger A; Arenas, Ernest; Linnarsson, Sten.

Cell ; 167(2): 566-580.e19, 2016 Oct 06.

Artigo em Inglês | MEDLINE | ID: mdl-27716510

2.

Trial of Lixisenatide in Early Parkinson's Disease.

Meissner, Wassilios G; Remy, Philippe; Giordana, Caroline; Maltête, David; Derkinderen, Pascal; Houéto, Jean-Luc; Anheim, Mathieu; Benatru, Isabelle; Boraud, Thomas; Brefel-Courbon, Christine; Carrière, Nicolas; Catala, Hélène; Colin, Olivier; Corvol, Jean-Christophe; Damier, Philippe; Dellapina, Estelle; Devos, David; Drapier, Sophie; Fabbri, Margherita; Ferrier, Vanessa; Foubert-Samier, Alexandra; Frismand-Kryloff, Solène; Georget, Aurore; Germain, Christine; Grimaldi, Stéphane; Hardy, Clémence; Hopes, Lucie; Krystkowiak, Pierre; Laurens, Brice; Lefaucheur, Romain; Mariani, Louise-Laure; Marques, Ana; Marse, Claire; Ory-Magne, Fabienne; Rigalleau, Vincent; Salhi, Hayet; Saubion, Amandine; Stott, Simon R W; Thalamas, Claire; Thiriez, Claire; Tir, Mélissa; Wyse, Richard K; Benard, Antoine; Rascol, Olivier.

N Engl J Med ; 390(13): 1176-1185, 2024 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-38598572

3.

Survival of a Novel Subset of Midbrain Dopaminergic Neurons Projecting to the Lateral Septum Is Dependent on NeuroD Proteins.

Khan, Shabana; Stott, Simon R W; Chabrat, Audrey; Truckenbrodt, Anna M; Spencer-Dene, Bradley; Nave, Klaus-Armin; Guillemot, François; Levesque, Martin; Ang, Siew-Lan.

J Neurosci ; 37(9): 2305-2316, 2017 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-28130357

4.

Evidence for a Notch1-mediated transition during olfactory ensheathing cell development.

Miller, Sophie R; Perera, Surangi N; Benito, Cristina; Stott, Simon R W; Baker, Clare V H.

J Anat ; 229(3): 369-83, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27271278

5.

Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.

Stott, Simon R W; Metzakopian, Emmanouil; Lin, Wei; Kaestner, Klaus H; Hen, Rene; Ang, Siew-Lan.

J Neurosci ; 33(18): 8022-34, 2013 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-23637192

6.

Time course of dopamine neuron loss and glial response in the 6-OHDA striatal mouse model of Parkinson's disease.

Stott, Simon R W; Barker, Roger A.

Eur J Neurosci ; 39(6): 1042-1056, 2014 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24372914

7.

Twelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson's Disease: The International Linked Clinical Trials Initiative.

Wyse, Richard K; Isaacs, Tom; Barker, Roger A; Cookson, Mark R; Dawson, Ted M; Devos, David; Dexter, David T; Duffen, Joy; Federoff, Howard; Fiske, Brian; Foltynie, Thomas; Fox, Susan; Greenamyre, J Timothy; Kieburtz, Karl; Kordower, Jeffrey H; Krainc, Dimitri; Matthews, Helen; Moore, Darren J; Mursaleen, Leah; Schwarzschild, Michael A; Stott, Simon R W; Sulzer, David; Svenningsson, Per; Tanner, Caroline M; Carroll, Camille; Simon, David K; Brundin, Patrik.

J Parkinsons Dis ; 14(4): 657-666, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38578902

8.

Parkinson's Disease Drug Therapies in the Clinical Trial Pipeline: 2023 Update.

McFarthing, Kevin; Buff, Susan; Rafaloff, Gary; Fiske, Brian; Mursaleen, Leah; Fuest, Rosie; Wyse, Richard K; Stott, Simon R W.

J Parkinsons Dis ; 13(4): 427-439, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37302040

9.

Parkinson's Disease Drug Therapies in the Clinical Trial Pipeline: 2022 Update.

McFarthing, Kevin; Rafaloff, Gary; Baptista, Marco; Mursaleen, Leah; Fuest, Rosie; Wyse, Richard K; Stott, Simon R W.

J Parkinsons Dis ; 12(4): 1073-1082, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35527571

10.

Waiting for PARIS-A Biological Target in Search of a Drug.

Wyse, Richard K; Stott, Simon R W; Mursaleen, Leah; Matthews, Helen; Dawson, Valina L; Dawson, Ted M.

J Parkinsons Dis ; 12(1): 95-103, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-34744054

11.

Polyclonal T-cell reconstitution of X-SCID recipients after in utero transplantation of lymphoid-primed multipotent progenitors.

Liuba, Karina; Pronk, Cornelis J H; Stott, Simon R W; Jacobsen, Sten-Eirik W.

Blood ; 113(19): 4790-8, 2009 May 07.

Artigo em Inglês | MEDLINE | ID: mdl-19074736

12.

Drug Repurposing for Parkinson's Disease: The International Linked Clinical Trials experience.

Stott, Simon R W; Wyse, Richard K; Brundin, Patrik.

Front Neurosci ; 15: 653377, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33815053

13.

Parkinson's Disease Drug Therapies in the Clinical Trial Pipeline: 2021 Update.

McFarthing, Kevin; Rafaloff, Gary; Baptista, Marco A S; Wyse, Richard K; Stott, Simon R W.

J Parkinsons Dis ; 11(3): 891-903, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34151864

14.

The wrong James Parkinson.

Stott, Simon R W.

Pract Neurol ; 15(2): 148, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25561574

15.

Novel approaches to counter protein aggregation pathology in Parkinson's disease.

Stott, Simon R W; Wyse, Richard K; Brundin, Patrik.

Prog Brain Res ; 252: 451-492, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32247372

16.

Parkinson's Disease Drug Therapies in the Clinical Trial Pipeline: 2020.

McFarthing, Kevin; Buff, Sue; Rafaloff, Gary; Dominey, Thea; Wyse, Richard K; Stott, Simon R W.

J Parkinsons Dis ; 10(3): 757-774, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32741777

17.

Hyperosmotic stress induces cell-dependent aggregation of α-synuclein.

Fragniere, Alexandra M C; Stott, Simon R W; Fazal, Shaline V; Andreasen, Maria; Scott, Kirsten; Barker, Roger A.

Sci Rep ; 9(1): 2288, 2019 02 19.

Artigo em Inglês | MEDLINE | ID: mdl-30783136

18.

Erythromyeloid-Derived TREM2: A Major Determinant of Alzheimer's Disease Pathology in Down Syndrome.

Raha-Chowdhury, Ruma; Henderson, James W; Raha, Animesh Alexander; Stott, Simon R W; Vuono, Romina; Foscarin, Simona; Wilson, Liam; Annus, Tiina; Fincham, Robert; Allinson, Kieren; Devalia, Vinod; Friedland, Robert P; Holland, Anthony; Zaman, Shahid H.

J Alzheimers Dis ; 61(3): 1143-1162, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29278889

19.

CD24 expression does not affect dopamine neuronal survival in a mouse model of Parkinson's disease.

Stott, Simon R W; Hayat, Shaista; Carnwath, Tom; Garas, Shaady; Sleeman, Jonathan P; Barker, Roger A.

PLoS One ; 12(2): e0171748, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28182766

20.

Neuroprotective Effect of TREM-2 in Aging and Alzheimer's Disease Model.

Raha, Animesh Alexander; Henderson, James W; Stott, Simon R W; Vuono, Romina; Foscarin, Simona; Friedland, Robert P; Zaman, Shahid H; Raha-Chowdhury, Ruma.

J Alzheimers Dis ; 55(1): 199-217, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-27662313

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