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1.
Bull Tokyo Dent Coll ; 2024 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-38749759

RESUMO

Although the working environment may play a role in dental acid erosion, few studies have been conducted on this in Japanese workers in recent years. The purpose of this study was to investigate oral health status, including dental erosion, in workers who may have been exposed to an acidic environment. The study participants were recruited by an online research company. Oral examinations and questionnaire surveys were conducted on this cohort in January 2023. A total of 144 participants were finally included. Workers exposed to an acidic environment showed more use of protective equipment and underwent more dental examinations at the workplace (p<0.001). Possible dental erosion was observed in only 3 out of the total of 144 participants (2.1%), however. No significant difference was observed in the number of teeth, caries experience, or dental erosion according to the number of years of acid exposure in the workplace. The results of this study suggest that acid exposure exerts a relatively small effect on the oral health status of workers in Japan.

2.
Angew Chem Int Ed Engl ; 63(14): e202401117, 2024 Apr 02.
Artigo em Inglês | MEDLINE | ID: mdl-38380969

RESUMO

A sequential process via photoredox catalysis and Lewis acid mediation for C-F bond transformation of the CF2 unit in perfluoroalkyl groups has been achieved to transform perfluoroalkylarenes into complex fluoroalkylated compounds. A phenothiazine-based photocatalyst promotes the defluoroaminoxylation of perfluoroalkylarenes with (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) under visible light irradiation, affording the corresponding aminoxylated products. These products undergo a further defluorinative transformation with various organosilicon reagents mediated by AlCl3 to provide highly functionalized perfluoroalkyl alcohols. Our novel phenothiazine catalyst works efficiently in the defluoroaminoxylation. Transient absorption spectroscopy revealed that the catalyst regeneration step is crucial for the photocatalytic aminoxylation.

3.
Bull Tokyo Dent Coll ; 63(4): 159-165, 2023 Jan 11.
Artigo em Inglês | MEDLINE | ID: mdl-36384758

RESUMO

Fixed partial dentures (FPDs) made of 12% Au-Pd alloy are covered under Japan's national health insurance system. The survival rate of such 3-unit fixed FPDs remains unknown, however. The purpose of this retrospective study was to assess their survival rate in the replacement of first molars. A total of 140 FPDs were included, and the endpoint was removal of an FPD. During the observation period, 43 FPDs were removed. The FPD survival rate was 70.2% at 10 yr, 58.2% at 15 yr, and 42.1% at 20 yr according to the Kaplan-Meier method. The estimated mean survival period was 19.4 yr. The main reasons for FPD loss were dental caries (27.9%), separation from the abutment tooth (18.6%), and pulpitis (18.6%). Single factor analysis using the log-rank test showed that two factors influenced FPD survival: a smaller gonial angle and deep pockets around the abutment teeth. This effect was not statistically significant in either case, however (p>0.05). The present results suggest that the prevention of caries and of the separation of the dentures from the abutment teeth are important factors in the long-term survival of FPDs.


Assuntos
Cárie Dentária , Prótese Parcial Fixa , Humanos , Dente Suporte , Falha de Restauração Dentária , Planejamento de Dentadura , Dente Molar , Estudos Retrospectivos , Taxa de Sobrevida
4.
Acta Radiol ; 63(10): 1363-1373, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34636644

RESUMO

BACKGROUND: The need for quantitative assessment of interstitial lung involvement on thin-section computed tomography (CT) has arisen in interstitial lung diseases including connective tissue disease (CTD). PURPOSE: To evaluate the capability of machine learning (ML)-based CT texture analysis for disease severity and treatment response assessments in comparison with qualitatively assessed thin-section CT for patients with CTD. MATERIAL AND METHODS: A total of 149 patients with CTD-related ILD (CTD-ILD) underwent initial and follow-up CT scans (total 364 paired serial CT examinations), pulmonary function tests, and serum KL-6 level tests. Based on all follow-up examination results, all paired serial CT examinations were assessed as "Stable" (n = 188), "Worse" (n = 98) and "Improved" (n = 78). Next, quantitative index changes were determined by software, and qualitative disease severity scores were assessed by consensus of two radiologists. To evaluate differences in each quantitative index as well as in disease severity score between paired serial CT examinations, Tukey's honestly significant difference (HSD) test was performed among the three statuses. Stepwise regression analyses were performed to determine changes in each pulmonary functional parameter and all quantitative indexes between paired serial CT scans. RESULTS: Δ% normal lung, Δ% consolidation, Δ% ground glass opacity, Δ% reticulation, and Δdisease severity score showed significant differences among the three statuses (P < 0.05). All differences in pulmonary functional parameters were significantly affected by Δ% normal lung, Δ% reticulation, and Δ% honeycomb (0.16 ≤r2 ≤0.42; P < 0.05). CONCLUSION: ML-based CT texture analysis has better potential than qualitatively assessed thin-section CT for disease severity assessment and treatment response evaluation for CTD-ILD.


Assuntos
Doenças do Tecido Conjuntivo , Doenças Pulmonares Intersticiais , Doenças do Tecido Conjuntivo/diagnóstico , Doenças do Tecido Conjuntivo/tratamento farmacológico , Humanos , Pulmão/diagnóstico por imagem , Doenças Pulmonares Intersticiais/diagnóstico por imagem , Doenças Pulmonares Intersticiais/terapia , Aprendizado de Máquina , Índice de Gravidade de Doença , Tomografia Computadorizada por Raios X/métodos
5.
Angew Chem Int Ed Engl ; 61(27): e202201883, 2022 07 04.
Artigo em Inglês | MEDLINE | ID: mdl-35485137

RESUMO

We have achieved the first anti-borylstannylation of alkynes by using (o-phenylenediaminato)borylstannanes. This reaction afforded 1-boryl-2-stannylalkenes with excellent regio- and stereoselectivity by a radical mechanism. This anti-addition manner is in sharp contrast to the syn-selectivity obtained during transition metal-catalyzed borylstannylation. The mild radical conditions enabled a broad substrate scope, and various types of aromatic and aliphatic alkynes were applicable. The origin of regio- and stereoselectivity was elucidated by DFT calculation of the reaction mechanism. The application of the borylstannylation products to cross- or homocoupling reactions provided ready access to either triarylethenes or bisborylbutadienes.


Assuntos
Alcinos , Elementos de Transição , Catálise
6.
J Am Chem Soc ; 143(25): 9308-9313, 2021 06 30.
Artigo em Inglês | MEDLINE | ID: mdl-34075740

RESUMO

Site-selective and direct C-F bond transformation of perfluoroalkylarenes was achieved with allylic stannanes via an iridium photoredox catalyst system. The present defluoroallylation proceeds exclusively at the benzylic position through perfluoroalkyl radicals generated by a single-electron transfer from an excited photoredox catalyst to perfluoroalkylarenes. A variety of perfluoroalkyl groups are applicable: linear perfluoroalkyl-substituted arenes such as Ar-nC4F9 and Ar-nC6F13 and heptafluoroisopropylarenes (Ar-CF(CF3)2) underwent site-selective defluoroallylation. DFT calculation studies revealed that the in situ generated Bu3SnF traps F- to prevent a retroreaction from the unstable perfluoroalkyl radical intermediate, and the radical intermediate favorably reacts with allylic stannanes. The synthesis of a bis(trifluoromethyl)methylene unit containing compound, which is an analog that is useful as a pharmaceutical agent for the prophylaxis or treatment of diabetes and inflammatory diseases, demonstrated the utility of this reaction.

7.
Bull Tokyo Dent Coll ; 62(4): 205-214, 2021 Dec 04.
Artigo em Inglês | MEDLINE | ID: mdl-34776474

RESUMO

The purpose of this study was to investigate the survival of removable partial dentures with a mandibular bilateral free end saddle (BFES) and abutment teeth in a clinical setting. Only mandibular dentures with a BFES were included (10 or fewer present teeth, and fewer than 4 occlusal units). The endpoints were replacement of denture and loss of abutment teeth. A total of 128 dentures and 595 abutment teeth were analyzed. Nineteen dentures had to be replaced during the observation period (mean duration: 11.4±6.9 years; range: 3 to 36 years). According to Kaplan-Meier analysis, the survival rate was 93.2% at 10 years and 68.6% at 20 years. The estimated mean survival period was 27.8 years. Single-factor analysis using the log-rank test showed that no factor investigated had a significant influence. The main reason for denture replacement was loss of abutment teeth (47.4%). The survival rate of the abutment teeth was 91.3% at 10 years and 77.3% at 20 years. The analysis revealed 4 significant risk factors: male sex (hazard ratio [HR]: 1.78); premolars (HR: 1.67); a lower number of abutment teeth (HR: 3.24); and history of endodontic treatment (HR: 2.79). The removable partial dentures with a mandibular BFES in this study lasted over 20 years, and their survival was influenced by loss of abutment teeth. Dentures are used continuously over long periods of time and should therefore be designed to allow easy adjustment when abutment teeth are lost.


Assuntos
Prótese Parcial Removível , Dente Suporte , Humanos , Masculino , Mandíbula , Estudos Retrospectivos , Taxa de Sobrevida
8.
Bull Tokyo Dent Coll ; 62(1): 55-60, 2021 Mar 13.
Artigo em Inglês | MEDLINE | ID: mdl-33583882

RESUMO

The relationship between public health expenditure and number of teeth was investigated in patients with diabetes mellitus using data obtained from the Japanese National Database of Health Insurance Claims and Specific Health Checkups. Data on medical, dental, and pharmacy claims generated between April 2015 and March 2016 were analyzed in patients with diabetes mellitus aged 50-74 years who used outpatient services during this period. Patients initiating medical and pharmacy claims related to diabetes mellitus were defined as having diabetes mellitus. Number of teeth was defined as number of teeth in conjunction with periodontitis due to the nature of the data source. Descriptive statistics were used to investigate the association between number of teeth and public health expenditure. Data on a total of 1,017,758 patients with diabetes mellitus were analyzed. Patients with the fewest teeth incurred higher medical expenses. The largest mean difference in medical expenditure was observed between patients with 5-9 teeth and those with over 28 teeth. The results of this study suggest that public health expenditure on patients with diabetes mellitus differs based on number of teeth.


Assuntos
Diabetes Mellitus , Gastos em Saúde , Idoso , Diabetes Mellitus/epidemiologia , Humanos , Pessoa de Meia-Idade , Pacientes Ambulatoriais
9.
Bull Tokyo Dent Coll ; 62(4): 235-243, 2021 Dec 04.
Artigo em Inglês | MEDLINE | ID: mdl-34776478

RESUMO

This report describes a validation study of data in the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) obtained by nationwide surveys on tooth extractions. The following 3 data sources on tooth extractions in Japan were compared: (1) the Nationwide Survey of the Reasons for Permanent Tooth Extractions in Japan (a previous survey conducted by the present authors); (2) the Statistics on Medical Care Activities in Public Health Insurance; and (3) the 4th NDB Open Data Japan. Source 1 was a nationwide survey conducted in 2018; sources 2 and 3 comprised data that are freely available for use by the public. In Source 1, 2,345 of 5,250 dentists approached responded to the questionnaire (recovery rate: 44.8%). The number of extracted teeth among younger age groups (aged 25-50 years) reported in Source 1 was lower than that in the other two sources. In contrast, the number of extracted teeth among older age groups reported in Source 1 was higher than that reported in the other two sources. However, when stratified by age group, all differences across the 3 sources regarding the mean annual number of tooth extractions were <0.05 teeth/year. The present results suggest that the NDB is a reliable resource for data on tooth extractions performed across the entire Japanese population.


Assuntos
Seguro Saúde , Extração Dentária , Bases de Dados Factuais , Japão/epidemiologia , Inquéritos e Questionários
10.
Clin Oral Investig ; 24(4): 1543-1549, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31352518

RESUMO

OBJECTIVES: The purpose of this study was to clinically investigate double-crown-retained removable partial dentures (DRPDs) and abutment teeth at dental clinics. MATERIALS AND METHODS: Only cases with complete arch reconstruction were included. Endpoints were replacement of denture and loss of abutment tooth. A total of 213 dentures with 1030 abutment teeth were analyzed. RESULTS: During the observation period, 32 dentures were replaced. The mean observation period was 12.7 (± 6.6) years (range 3 to 36). By the Kaplan-Meier method, survival rate at 10 years was 94.7% and at 20 years was 70.8%. Estimated mean survival period was 27.1 years. Cox regression analysis showed that risk factor for replacement was good occlusion as indicated by Eichner index groups A to B3 (HR 2.81). The main reason for denture replacement was loss of abutment teeth. Survival rate of abutment teeth at 10 years was 83.8% and at 20 years was 66.3%. The analysis revealed six risk factors: male gender (HR 1.76), age range 65-89 years (HR 1.51), posterior teeth (HR 1.60), higher number of present teeth in opposite jaw (HR 1.69), lower number of abutment teeth (HR 1.76), and short inner crown (HR 2.28). CONCLUSION: DRPDs last over 20 years, making them a durable investment in one's oral health; their survival is influenced by loss of abutment teeth. CLINICAL RELEVANCE: In cases where there are few teeth remaining in a jaw, DRPDs represent a suitable treatment that makes use of the remaining teeth, even if the abutment teeth are non-vital.


Assuntos
Coroas , Dente Suporte , Prótese Parcial Removível , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Perda de Dente
11.
Bull Tokyo Dent Coll ; 61(3): 187-193, 2020 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-32814724

RESUMO

It has been reported that people who brush their teeth frequently might be more health-conscious and maintain healthier lifestyle habits. The relationship between obesity and oral health behavior in childhood is unknown, however. The aim of the present study was to fill this gap by investigating obesity and factors associated with oral health behavior in Japanese primary and junior high school students. A total of 475 primary school students (fifth-grade, age 10-11 years) and 408 junior high school students (first-grade, age 12-13 years) were included. All the participants underwent a regular health check-up and completed a self-reported questionnaire. The data thus obtained were subjected to multiple logistic regression analyses to identify the relationship between obesity and factors associated with oral health behavior. In primary school students, a dislike of physical activity was the only factor showing a significant association with obesity (p<0.05). In addition, however, tooth brushing <2 times per day and a lack of regular clinical dental care showed a significant association with obesity in junior high school students (p<0.05). The present results suggest a significant association between regular clinical dental care and tooth brushing and obesity in junior school students.


Assuntos
Obesidade , Estudantes , Criança , Estudos Transversais , Comportamentos Relacionados com a Saúde , Humanos , Saúde Bucal , Inquéritos e Questionários
12.
Bull Tokyo Dent Coll ; 61(3): 153-160, 2020 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-32801262

RESUMO

The purpose of this study was to investigate the relationship among the waist-to-height ratio (WHtR) and the body mass index (BMI) as obesity indicators and gingival inflammation as determined by bleeding on probing (BOP). The participants comprised employees of a milk products company based in Tokyo, Japan. A total of 159 non-diabetic men aged 40 to 59 yr and with a minimum of 28 teeth were included. Multiple logistic regression analysis controlling for age, smoking status, pocket depth, frequency of daily brushing, frequency of weekly interdental brushing, and regular dental attendance was performed to compare the relationships among the obesity indicators and BOP. Participants with good oral hygiene had significantly less BOP than those with poor oral hygiene (p<0.001). No significant differences were observed among the other items investigated. A significant association was observed between WHtR and BOP (odds ratio: 2.40, 95% confidence interval: 1.11-5.22); no such association was observed with the BMI, however. The present results showed that obesity, as determined according to a visceral fat index, was associated with BOP, but not with BMI. This suggests that the WHtR is a more accurate index of obesity than the BMI in studies on BOP.


Assuntos
Gengivite , Obesidade , Adulto , Humanos , Inflamação , Japão , Masculino , Pessoa de Meia-Idade , Tóquio
13.
Bull Tokyo Dent Coll ; 60(4): 261-266, 2019 Dec 10.
Artigo em Inglês | MEDLINE | ID: mdl-31761892

RESUMO

Active oxygen and free radicals are involved in metabolism in cells and tissues. Immunohistological studies of related enzymes are few, and the morphological dynamics of these enzymes in dental pulp and odontoblasts remain to be elucidated. Nitric oxide synthase (NOS) has 3 isoforms: nNOS, iNOS, and eNOS. The aim of this study was to investigate the profiles of NOS isoforms in the absence of nNOS in dental pulp and odontoblasts. Five-week-old male C57BL/6 and nNOS knockout (KO) mice were sacrificed and expression of nNOS, iNOS, and eNOS determined immunohistochemically. Expression of nNOS was positive, whereas that of iNOS was negative and eNOS weakly positive in the dental pulp and odontoblasts of the control mice. In nNOS KO mice, expression of iNOS was positive in dental pulp and strongly positive in odontoblasts, whereas that of eNOS was stronger in fibroblasts, endothelial cells in the vicinity of blood vessels in the dental pulp, and odontoblasts. Expression of nNOS was negative in the nNOS KO mice. This suggests that iNOS and eNOS compensate for nNOS deficiency in vascular endothelial cells and fibroblasts in the dental pulp and odontoblasts.


Assuntos
Polpa Dentária , Odontoblastos , Animais , Células Endoteliais , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Camundongos Knockout , Óxido Nítrico Sintase , Isoformas de Proteínas
14.
Bull Tokyo Dent Coll ; 60(4): 297-302, 2019 Dec 10.
Artigo em Inglês | MEDLINE | ID: mdl-31761880

RESUMO

The purpose of this study was to investigate the effectiveness of the Communication Studies Program at Tokyo Dental College as a tool in behavioral education. The number of Patient Community members who had participated in multiple sets of the program for third-year students in the same year within the 3-year period spanning 2016 to 2018 (152, 148, and 129 students in 2016, 2017, and 2018 respectively), and the period during which they had participated in multiple sets were investigated. Comments on student behavior, including on hairstyle, clothes, and attitude, were also analyzed. The total number of members who had participated in multiple sets (1 set comprised 1 lecture and 2 training sessions) was 5; and their comments were more favorable during the second (sets 3 and 4) than the first half of the 1-month program (sets 1 and 2). During the first half, the students were criticized for speaking softly, having bad posture, not concentrating, and having an attitude inappropriate for a medical worker; but in the second half, they were praised for beginning to adopt the proper attitude for a medical worker, speaking louder, having better posture, and a very serious attitude. These findings suggest that the Communication Studies Program is effective in improving student behavior.


Assuntos
Faculdades de Odontologia , Humanos , Tóquio
15.
Bull Tokyo Dent Coll ; 60(3): 153-161, 2019 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-31308308

RESUMO

The purpose of this study was to identify factors associated with untreated decayed teeth (DT) in male sales workers. The participants were recruited by screening a pool of Japanese registrants in an online database for eligibility for inclusion in the study. Between 20 February 2015 and 11 March 2015, those deemed eligible were asked to complete a questionnaire on the status of their oral health. Responses from a total of 142 male sales workers aged between 30 and 49 years were analyzed. Of these, 40 reported DT and 102 no untreated decayed teeth (NDT). The percentage of participants with DT was higher than that with NDT among night shift workers (p<0.001). A higher percentage of participants with DT reported pain when eating or drinking something cold (p=0.041), pain in the teeth or gingiva (p<0.001), or frequent stomatitis (p=0.030). A higher percentage of participants with DT reported eating between meals (p=0.027) and a lower percentage visiting a dental clinic in the past 6 months (p=0.017) compared with among participants with NDT. Those with NDT were more likely to report an inability to visit a dental clinic when they wanted to (p=0.033), but those with DT were more likely to report that their reasons for not visiting a dental clinic were that multiple visits were required for treatment (p=0.012) or that they did not like the treatment (p=0.005). Working the night shift (Odds Ratio [OR], 3.492; 95% Confidence Interval [CI], 1.347-8.725) and visiting a dental clinic in the past 6 months (OR, 0.084; 95%CI, 0.010-0.733) were identified as independent variables correlated with leaving DT untreated. Requiring oral health education and dental checkups at least once every 6 months may have a positive effect on oral health among male sales workers, especially those doing night shifts.


Assuntos
Cárie Dentária , Adulto , Educação em Saúde Bucal , Humanos , Internet , Masculino , Pessoa de Meia-Idade , Saúde Bucal , Inquéritos e Questionários
16.
Bull Tokyo Dent Coll ; 60(2): 89-96, 2019 Jun 21.
Artigo em Inglês | MEDLINE | ID: mdl-30971676

RESUMO

The purpose of this cross-sectional study was to determine whether there is an association between hemoglobin A1c (HbA1c) level and the presence or absence of decayed teeth in patients with type 2 diabetes mellitus. The patients and data on their age and sex, the presence or absence of dental claims, medical history of diabetes mellitus, and workplace dental examinations were obtained from a Japanese healthcare database available for epidemiological studies. The HbA1c levels were obtained from results of the Specific Health Checkups and Specific Health Guidance tests conducted by the Japanese Ministry of Health, Labour and Welfare. Data on a total of 1,897 patients were analyzed. Patients with poorly controlled diabetes (HbA1c≥6.5, n=779) had more decayed teeth than those in whom it was well controlled (HbA1c<6.5, n=1,118). Multiple logistic regression analysis with the presence or absence of decayed teeth as a dependent variable revealed a significant association between an HbA1c level of ≥8.0 and decayed teeth (odds ratio: 1.69; 95% confidence interval, 1.24-2.29), even after adjusting for dental attendance. This suggests that a poorly controlled blood HbA1c level is a risk factor for dental caries. More thorough oral hygiene instruction and education on preventive treatment for dental caries in patients with poorly controlled diabetes are needed.


Assuntos
Cárie Dentária , Diabetes Mellitus Tipo 2 , Estudos Transversais , Hemoglobinas Glicadas , Humanos , Fatores de Risco
17.
AJR Am J Roentgenol ; 210(2): W45-W53, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29220212

RESUMO

OBJECTIVE: The objective of this study was to compare the capability of xenon-enhanced area-detector CT (ADCT) performed with a subtraction technique and coregistered 81mKr-ventilation SPECT/CT for the assessment of pulmonary functional loss and disease severity in smokers. SUBJECTS AND METHODS: Forty-six consecutive smokers (32 men and 14 women; mean age, 67.0 years) underwent prospective unenhanced and xenon-enhanced ADCT, 81mKr-ventilation SPECT/CT, and pulmonary function tests. Disease severity was evaluated according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification. CT-based functional lung volume (FLV), the percentage of wall area to total airway area (WA%), and ventilated FLV on xenon-enhanced ADCT and SPECT/CT were calculated for each smoker. All indexes were correlated with percentage of forced expiratory volume in 1 second (%FEV1) using step-wise regression analyses, and univariate and multivariate logistic regression analyses were performed. In addition, the diagnostic accuracy of the proposed model was compared with that of each radiologic index by means of McNemar analysis. RESULTS: Multivariate logistic regression showed that %FEV1 was significantly affected (r = 0.77, r2 = 0.59) by two factors: the first factor, ventilated FLV on xenon-enhanced ADCT (p < 0.0001); and the second factor, WA% (p = 0.004). Univariate logistic regression analyses indicated that all indexes significantly affected GOLD classification (p < 0.05). Multivariate logistic regression analyses revealed that ventilated FLV on xenon-enhanced ADCT and CT-based FLV significantly influenced GOLD classification (p < 0.0001). The diagnostic accuracy of the proposed model was significantly higher than that of ventilated FLV on SPECT/CT (p = 0.03) and WA% (p = 0.008). CONCLUSION: Xenon-enhanced ADCT is more effective than 81mKr-ventilation SPECT/CT for the assessment of pulmonary functional loss and disease severity.


Assuntos
Doença Pulmonar Obstrutiva Crônica/diagnóstico por imagem , Doença Pulmonar Obstrutiva Crônica/fisiopatologia , Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único , Fumantes , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Criptônio , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Testes de Função Respiratória , Índice de Gravidade de Doença , Xenônio
18.
Bull Tokyo Dent Coll ; 59(1): 59-61, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29563363

RESUMO

Diagnosing vertical root fracture (VRF) is difficult. Here, we retrospectively investigated the duration from initial symptoms to a definite diagnosis of VRF in dental offices. Data were collected on patients with VRF between July 2013 and June 2015. Initial symptoms were ascertained from clinical records. The focus was on the maxillary second premolars and mesial roots of the mandibular first molars, where VRF is most frequent. All VRF in the bilateral dentition was analyzed. Only cases in which the buccal-lingual plane of the root was fractured were included. Data from 31 dental offices revealed a total of 39 VRFs in the maxillary second premolars and 43 in the mandibular mesial roots of the first molars. The patients comprised 42 males and 40 females, and the average age was 59.7±11.6 years at initial onset of symptoms. The mean duration from initial symptoms to a definite diagnosis in the maxillary second premolars was 18.3±22.5 months, while that in the mandibular first molars was 16.1±17.8 months. The cumulative diagnostic rate was 48.7% at 12 months and 79.5% at 24 months in the maxillary second premolars, and 38.1% at 12 months and 86.0% at 24 months in the mandibular first molars. No significant difference was observed between tooth type. If VRF is suspected, doctors should explain the risks of tooth extraction and begin considering treatment options. The present results revealed that 80% of VRFs were diagnosed within 2 years of initial onset of symptoms.


Assuntos
Dente Pré-Molar/lesões , Dente Molar/lesões , Fraturas dos Dentes/diagnóstico , Raiz Dentária/lesões , Estudos de Coortes , Consultórios Odontológicos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Tempo
19.
Bull Tokyo Dent Coll ; 59(4): 229-236, 2018 Nov 30.
Artigo em Inglês | MEDLINE | ID: mdl-30333368

RESUMO

The purpose of this study was to determine the distribution of healthy elderly individuals undergoing regular dental check-ups and identify any environmental or associated oral factors. A cross-sectional questionnaire survey was used to interview 216 individuals attending 2 welfare facilities for the elderly, of whom 160 were included in the final analysis. Items comprised age, sex, number of residual teeth, frequency of teeth/denture cleaning, subjective chewing ability, denture use, oral status, regular dental check-ups, visitation of the same dentist, number of dental visits in the past year, General Oral Health Assessment Index (GOHAI) (Japanese version) score, living situation, and use of routine medication. Individuals undergoing regular dental check-ups were defined as those with a primary dentist whom they saw for dental check-ups at least once a year. The rate of individuals undergoing regular dental check-ups was 75.0% in men aged 60-74 years, 58.8% in women aged 60-74 years, 70.0% in men aged 75 years or over, and 45.3% in women aged 75 years or over. Logistic regression analysis revealed a higher number of residual teeth (odds ratio [OR]=2.664 in comparison with those with fewer than 20 teeth, p=0.0427); cleaning teeth/dentures 3 or more times per day (OR=2.546 in comparison with cleaning them twice per day or less, p=0.0157); and a higher GOHAI score (OR=2.742 in comparison with those with a GOHAI score of less than 58, p=0.0263) as factors significantly correlated with undergoing regular dental check-ups. In conclusion, the results revealed that individuals undergoing regular dental check-ups had 20 or more residual teeth, cleaned their teeth/denture 3 or more times per day, and had a higher GOHAI score. This indicates that the best predictive factor for undergoing regular dental check-ups in healthy elderly individuals is their GOHAI score.


Assuntos
Assistência Odontológica para Idosos/estatística & dados numéricos , Prótese Parcial Removível/psicologia , Saúde Bucal/estatística & dados numéricos , Qualidade de Vida , Idoso , Atitude Frente a Saúde , Estudos Transversais , Profilaxia Dentária/estatística & dados numéricos , Higienizadores de Dentadura , Prótese Total/psicologia , Feminino , Humanos , Japão , Modelos Logísticos , Masculino , Mastigação/fisiologia , Pessoa de Meia-Idade , Razão de Chances , Inquéritos e Questionários
20.
Eur Radiol ; 27(7): 2978-2988, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-27913913

RESUMO

OBJECTIVES: To determine the value of a raw data-based metal artifact reduction (SEMAR) algorithm for image quality improvement in abdominal CT for patients with small metal implants. METHODS: Fifty-eight patients with small metal implants (3-15 mm in size) who underwent treatment for hepatocellular carcinoma were imaged with CT. CT data were reconstructed by filtered back projection with and without SEMAR algorithm in axial and coronal planes. To evaluate metal artefact reduction, mean CT number (HU and SD) and artefact index (AI) values within the liver were calculated. Two readers independently evaluated image quality of the liver and pancreas and visualization of vasculature using a 5-point visual score. HU and AI values and image quality on images with and without SEMAR were compared using the paired Student's t-test and Wilcoxon signed rank test. Interobserver agreement was evaluated using linear-weighted κ test. RESULTS: Mean HU and AI on images with SEMAR was significantly lower than those without SEMAR (P < 0.0001). Liver and pancreas image qualities and visualizations of vasculature were significantly improved on CT with SEMAR (P < 0.0001) with substantial or almost perfect agreement (0.62 ≤ κ ≤ 0.83). CONCLUSIONS: SEMAR can improve image quality in abdominal CT in patients with small metal implants by reducing metallic artefacts. KEY POINTS: • SEMAR algorithm significantly reduces metallic artefacts from small implants in abdominal CT. • SEMAR can improve image quality of the liver in dynamic CECT. • Confidence visualization of hepatic vascular anatomies can also be improved by SEMAR.


Assuntos
Abdome/diagnóstico por imagem , Algoritmos , Artefatos , Carcinoma Hepatocelular/diagnóstico , Neoplasias Hepáticas/diagnóstico , Próteses e Implantes , Tomografia Computadorizada por Raios X/normas , Idoso , Carcinoma Hepatocelular/terapia , Terapia Combinada , Feminino , Humanos , Processamento de Imagem Assistida por Computador , Neoplasias Hepáticas/terapia , Masculino , Metais , Pessoa de Meia-Idade , Curva ROC , Reprodutibilidade dos Testes , Estudos Retrospectivos
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