Detalhe da pesquisa
1.
Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer.
Nat Chem Biol
; 19(3): 292-300, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36280791
2.
Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells.
EMBO Rep
; 24(10): e56279, 2023 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37489735
3.
Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration.
J Hepatol
; 78(5): 1028-1036, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36702176
4.
Phase II proof-of-concept study of atorvastatin in castration-resistant prostate cancer.
BJU Int
; 131(2): 236-243, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35844167
5.
Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features.
Mol Cell Proteomics
; 11(6): M111.015131, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22223895
6.
Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing.
Nat Commun
; 15(1): 1931, 2024 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38431691
7.
ACOD1 deficiency offers protection in a mouse model of diet-induced obesity by maintaining a healthy gut microbiota.
Cell Death Dis
; 15(2): 105, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38302438
8.
PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle.
Cell Rep
; 43(3): 113868, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38421868
9.
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma.
Nat Cancer
; 5(4): 659-672, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38286828
10.
Influence of various endogenous and artefact modifications on large-scale proteomics analysis.
Rapid Commun Mass Spectrom
; 27(3): 443-50, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23280976
11.
Pyruvate transamination and NAD biosynthesis enable proliferation of succinate dehydrogenase-deficient cells by supporting aerobic glycolysis.
Cell Death Dis
; 14(7): 403, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37414778
12.
Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells.
Nat Commun
; 14(1): 4634, 2023 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37591854
13.
Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade.
bioRxiv
; 2023 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993533
14.
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target.
Nat Metab
; 5(8): 1303-1318, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37580540
15.
Multi-omics & pathway analysis identify potential roles for tumor N-acetyl aspartate accumulation in murine models of castration-resistant prostate cancer.
iScience
; 25(4): 104056, 2022 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35345457
16.
Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression.
Cancer Res
; 82(14): 2565-2575, 2022 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35675421
17.
Mesenchymal stromal cells cultured in physiological conditions sustain citrate secretion with glutamate anaplerosis.
Mol Metab
; 63: 101532, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35752287
18.
THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer.
EMBO Mol Med
; 14(3): e14764, 2022 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35014179
19.
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix.
Nat Metab
; 4(6): 693-710, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35760868
20.
The dioxygenase-encoding olsD gene from Burkholderia cenocepacia causes the hydroxylation of the amide-linked fatty acyl moiety of ornithine-containing membrane lipids.
Biochemistry
; 50(29): 6396-408, 2011 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21707055