Prevalence of diabetes mellitus among Uygur children in Hotan Prefecture of Xinjiang, China. / æ–°ç–†å’Œç”°åœ°åŒºç»´å¾å°”æ—å„¿ç«¥ç³–å°¿ç— æ‚£ç— çŽ‡è°ƒæŸ¥.

OBJECTIVES: To investigate the prevalence of diabetes mellitus (DM) among Uygur children in Hotan Prefecture of Xinjiang, China, as well as the factors influencing the development of DM. METHODS: The cluster random sampling method was used to select 5 308 children, aged 4-18 years, from the middle and primary schools and kindergartens in Hotan Prefecture of Xinjiang. The survey methods included questionnaire survey and the measurement of height and weight. All subjects were tested for fasting fingertip blood glucose to investigate the prevalence of DM and impaired fasting glucose (IFG). RESULTS: A total of 5 184 valid questionnaires were collected. Fourteen children (0.27%) were found to have DM, among whom 8 had type 1 DM, 2 had type 2 DM, and 4 had unclassified DM. Twenty-nine children (0.56%) were found to have IFG. There was no significant difference in the prevalence rate of DM and IFG between boys and girls (P>0.05). The prevalence rate of DM was 0.18% in the 4-<10 years group, 0.47% in the 10-<15 years group, and 0.07% in the 15-18 years group (P=0.072).The prevalence rate of IFG in the above three age groups was 0.18%, 0.94%, and 0.42%, respectively, with a significant difference among groups (P=0.007). The proportion of family history of DM and the proportion of overweight/obesity in children with DM were significantly higher than those in children without DM (P<0.05), while the proportion of children with DM who preferred coarse grains was significantly lower than that in children without DM (P<0.05). CONCLUSIONS: The prevalence of DM and IFG in Uyghur children in Hotan Prefecture of Xinjiang is relatively low. There is no significant difference in the prevalence of DM among children of different genders or age groups, but the prevalence of IFG in children of different age groups is different. A family history of DM, overweight or obesity, and low intake of coarse grains might be associated with the development of DM.

[Comparison of immunomagnetic beads and hespan precipitation for isolation of mononuclear cells from umbilical cord blood].

OBJECTIVE: To compare the characteristics of immunomagnetic beads and hespan precipitation for isolation of mononuclear cells (MNCs) from umbilical cord blood and try to find a better isolation method for MNCs. METHODS: Fifteen umbilical cord blood samples from healthy parturiens were collected between December 2007 and March 2008. MNCs were isolated using hespan precipitation and CD133 immunomagnetic beads, respectively. MNCs were identified using the surface marker CD34 by flow cytometry on the 30th of primary culture. Growth conditions and morphologic changes of primary cells were observed by an inverted microscope. RESULTS: The number of MNCs from umbilical cord blood isolated by hespan precipitation (15.23 +/- 4.30 x 10(6)/mL) was significantly greater than that by CD133 immunomagnetic beads (0.066 +/- 0.027 x 10(6)/mL) (p<0.05). The MNCs isolated by hespan precipitation suspended at the culture medium and their growth was slow after passage. The growth of MNCs isolated by CD133 immunomagnetic beads was kept in a good condition. The CD34 positive rate of MNCs isolated by hespan precipitation and immunomagnetic beads was 10.1% and 0.5%, respectively. CONCLUSIONS: The hespan precipitation is an effective method for MNCs isolation from human umbilical cord blood, but with a cell growth condition below the mark. The MNCs isolated by CD133 immunomagnetic beads are in a high purity quotient.

Bis[µ-2-(3-pyridylmeth-yl)-2H-benzo-triazole]bis-[nitratosilver(I)].

In the title centrosymmetric binuclear Ag(I) complex, [Ag(2)(NO(3))(2)(C(12)H(10)N(4))(2)], each Ag(I) center is coordinated by one pyridine and one benzotriazole N-donor atom of two inversion-related 2-(3-pyridylmeth-yl)-2H-benzotriazole (L) ligands, and an O atom of a coordinated NO(3) (-) anion in a distorted T-shaped geometry. This forms a unique box-like cyclic dimer with an intra-molecular non-bonding Ag⋯Ag separation of 6.327 (2) Å. Weak inter-molecular Ag⋯O(nitrate) inter-actions [2.728 (4) and 2.646 (3) Å] link the binuclear units, forming a two-dimensional network parallel to (100). Inter-molecular C-H⋯O hydrogen-bonding inter-actions, involving the L ligands and the coordinated NO(3) (-) anions, link the sheets, forming a three-dimensional framework.

Dichlorido[1-(1-naphthyl-meth-yl)-3-(2-pyrid-yl)-1H-pyrazole-κN,N]palladium(II).

In the title compound, [PdCl(2)(C(19)H(15)N(3))], the Pd(II) centre is four-coordinated by two N-atom donors from one 1-[3-(2-pyrid-yl)pyrazol-1-ylmeth-yl]naphthalene (L) ligand and by two Cl atoms in a distorted square-planar coordination geometry. In the crystal structure, adjacent Pd(II) mononuclear units form inter-molecular C-H⋯π inter-actions involving the benzene and pyridine rings of different L ligands and π-π stacking inter-actions between the pyrazolyl-pyridine and naphthalene rings of neighbouring L ligands, with a centroid-centroid separation of 3.522 (1) Å.

Nanofibrous patterns by direct electrospinning of nanofibers onto topographically structured non-conductive substrates.

Patterning of electrospun nanofibers has recently attracted much attention for its usefulness in a wide range of applications. This paper reports on the generation of spatially defined nanofibrous patterns by direct deposition of electrospun nanofibers onto a variety of insulating substrates. It was found that topographical features of different non-conducting substrates could be readily replicated by the electrospun nanofibers of interest. To elucidate the underlying mechanism of nanofiber patterning, we have systematically studied the effects of surface topography of non-conducting substrates (in particular protrusions) on the nanofiber deposition and assembly. Results from experiments and electric field simulation indicated that under a strong electric field the insulating substrates can be polarized, which could consequently affect the distribution of the original electric field. For particular non-conductive substrates with small mesh sizes or sufficient thickness, surface topography of the dielectric substrate may play a key role in determining the deposition and the arrangement of electrospun fibers. In addition, parameters that could influence the fineness of nanofibrous patterns have also been investigated. This contribution is believed to warrant further scientific understanding of the patterning mechanism of electrospun nanofibers, and to allow for design of specific and complex non-conductive substrate collectors for easy generation of patterned nanofibrous architectures, applicable in a variety of areas such as tissue engineering scaffolds and optoelectronic displays.