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5.
Indian J Malariol ; 27(4): 217-22, 1990 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-2093005

RESUMO

A number of growth promoting substances used in plant tissue culture were investigated for their effect on cultures of malaria parasites. In all, seven such growth promoting substances were employed. Out of these, only three substances, namely indoleacetic acid, indolebutyric acid and gibberellic acid improved P. falciparum growth in vitro.


Assuntos
Eritrócitos/parasitologia , Substâncias de Crescimento/farmacologia , Plasmodium falciparum/efeitos dos fármacos , Animais , Células Cultivadas , Meios de Cultura , Plasmodium falciparum/crescimento & desenvolvimento
6.
Indian J Malariol ; 29(2): 73-82, 1992 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-1459308

RESUMO

To date RPMI-1640 has been the best medium for cultivation of Plasmodium falciparum in vitro. In addition to this medium, several alternative media, essentially the ones used in animal and plant tissue culture, were employed for the cultivation of P. falciparum. Only the media rich in glucose content, viz. Nitsch medium and White's medium S-3, supported the parasite multiplication.


Assuntos
Meios de Cultura , Plasmodium falciparum/crescimento & desenvolvimento , Animais , Estudos de Avaliação como Assunto , Técnicas In Vitro , Parasitologia/métodos
7.
Chemotherapy ; 35(3): 160-3, 1989.
Artigo em Inglês | MEDLINE | ID: mdl-2670480

RESUMO

A modified Rieckmann test was developed for assessing chloroquine sensitivity of Plasmodium vivax strains. This test envisages the evaluation of parasite growth with different concentrations of the drug and its comparison with controls, at the end of a 48-hour experimental period. Using this test, 16 strains were assessed for their chloroquine sensitivity. Twelve strains were found to be sensitive, and 4 were resistant to chloroquine.


Assuntos
Antimaláricos/farmacologia , Plasmodium vivax/efeitos dos fármacos , Animais , Resistência a Medicamentos
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