Detalhe da pesquisa
1.
Induction of Transcriptional Inhibitor HES1 and the Related Repression of Tumor-Suppressor TXNIP Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase NPM-ALK.
Am J Pathol
; 192(8): 1186-1198, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35640677
2.
Yersinia effector protein (YopO)-mediated phosphorylation of host gelsolin causes calcium-independent activation leading to disruption of actin dynamics.
J Biol Chem
; 292(19): 8092-8100, 2017 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28280241
3.
Tilapia and human CLIC2 structures are highly conserved.
Biochem Biophys Res Commun
; 495(2): 1752-1757, 2018 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29198705
4.
Avathrin: a novel thrombin inhibitor derived from a multicopy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum.
FASEB J
; 31(7): 2981-2995, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28363953
5.
Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis.
Nature
; 483(7389): 355-8, 2012 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22388816
6.
Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5).
Proc Natl Acad Sci U S A
; 112(48): 14834-9, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26578813
7.
Affinity Selection of FGF2-Binding Heparan Sulfates for Ex Vivo Expansion of Human Mesenchymal Stem Cells.
J Cell Physiol
; 232(3): 566-575, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27291835
8.
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication.
PLoS Pathog
; 11(3): e1004682, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25775415
9.
Discovery of Mycobacterium tuberculosis α-1,4-glucan branching enzyme (GlgB) inhibitors by structure- and ligand-based virtual screening.
J Biol Chem
; 290(1): 76-89, 2015 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25384979
10.
Plant immunophilins: a review of their structure-function relationship.
Biochim Biophys Acta
; 1850(10): 2145-58, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25529299
11.
Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication.
J Virol
; 89(20): 10717-21, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269182
12.
Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - experimental validation in human breast and colon cancer.
Biosci Biotechnol Biochem
; 80(11): 2122-2131, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27362887
13.
Structural determinants of heparin-transforming growth factor-ß1 interactions and their effects on signaling.
Glycobiology
; 25(12): 1491-504, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26306634
14.
Crystal structure of Arabidopsis cyclophilin38 reveals a previously uncharacterized immunophilin fold and a possible autoinhibitory mechanism.
Plant Cell
; 24(6): 2666-74, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22706283
15.
Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule.
J Biol Chem
; 287(17): 13611-9, 2012 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22362761
16.
NMR structure of Carcinoscorpius rotundicauda thioredoxin-related protein 16 and its role in regulating transcription factor NF-κB activity.
J Biol Chem
; 287(35): 29417-28, 2012 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22763700
17.
Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design.
Mol Cell Proteomics
; 10(3): M110.004390, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21081668
18.
A NR2E1-interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells.
Cell Prolif
; 56(1): e13350, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36321378
19.
Crystal structure of mouse RhoA:GTPγS complex in a centered lattice.
J Struct Funct Genomics
; 13(4): 241-5, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23001747
20.
Lack of TNFalpha expression protects anaplastic lymphoma kinase-positive T-cell lymphoma (ALK+ TCL) cells from apoptosis.
Proc Natl Acad Sci U S A
; 106(37): 15843-8, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19717436