Detalhe da pesquisa
1.
Engineered Wnt7a ligands rescue blood-brain barrier and cognitive deficits in a COVID-19 mouse model.
Brain
; 147(5): 1636-1643, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38306655
2.
Endothelial Cell APOE3 Regulates Neurovascular, Neuronal, and Behavioral Function.
Arterioscler Thromb Vasc Biol
; 43(10): 1952-1966, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37650329
3.
Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease.
Mol Ther
; 29(5): 1883-1902, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33508430
4.
EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer's disease.
J Lipid Res
; 58(9): 1733-1755, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28389477
5.
The role of APOE in cerebrovascular dysfunction.
Acta Neuropathol
; 131(5): 709-23, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26884068
6.
Amyloid-ß pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo.
J Biol Chem
; 289(44): 30538-30555, 2014 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25217640
7.
APOE-modulated Aß-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective.
J Neurochem
; 133(4): 465-88, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25689586
8.
Levels of soluble apolipoprotein E/amyloid-ß (Aß) complex are reduced and oligomeric Aß increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
J Biol Chem
; 288(8): 5914-26, 2013 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23293020
9.
Human APOE4 increases microglia reactivity at Aß plaques in a mouse model of Aß deposition.
J Neuroinflammation
; 11: 111, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24948358
10.
Higher Neuronal Facilitation and Potentiation with APOE4 Suppressed by Angiotensin II.
Mol Neurobiol
; 61(1): 120-131, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37589833
11.
Induced saturation transfer recovery steady states (iSTRESS) for proton exchange rate mapping with CEST MRI, a preliminary study.
Magn Reson Imaging
; 109: 264-270, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38522624
12.
APOE2 Heterozygosity Reduces Hippocampal Soluble Amyloid-ß42 Levels in Non-Hyperlipidemic Mice.
J Alzheimers Dis
; 97(4): 1629-1639, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38306049
13.
Estradiol improves behavior in FAD transgenic mice that express APOE3 but not APOE4 after ovariectomy.
Front Endocrinol (Lausanne)
; 15: 1374825, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38742194
14.
Caveolin-1 mediates blood-brain barrier permeability, neuroinflammation, and cognitive impairment in SARS-CoV-2 infection.
J Neuroimmunol
; 388: 578309, 2024 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38335781
15.
APOE4-specific changes in Aß accumulation in a new transgenic mouse model of Alzheimer disease.
J Biol Chem
; 287(50): 41774-86, 2012 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23060451
16.
Preferential interactions between ApoE-containing lipoproteins and Aß revealed by a detection method that combines size exclusion chromatography with non-reducing gel-shift.
Biochim Biophys Acta
; 1821(2): 295-302, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22138302
17.
Higher Neuronal Facilitation and Potentiation with APOE4 Suppressed by Angiotensin II.
Res Sq
; 2023 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292788
18.
A small-molecule TLR4 antagonist reduced neuroinflammation in female E4FAD mice.
Alzheimers Res Ther
; 15(1): 181, 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37858252
19.
APOE genotype and sex modulate Alzheimer's disease pathology in aged EFAD transgenic mice.
Front Aging Neurosci
; 15: 1279343, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38020764
20.
APOE genotype alters glial activation and loss of synaptic markers in mice.
Glia
; 60(4): 559-69, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22228589