Detalhe da pesquisa
1.
Acute and Direct Effects of Sodium-Glucose Cotransporter 2 Inhibition on Glomerular Filtration Rate in Spontaneously Diabetic Torii Fatty Rats.
Biol Pharm Bull
; 42(10): 1707-1712, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31582658
2.
In Vitro Pharmacological Profile of Ipragliflozin, a Sodium Glucose Co-transporter 2 Inhibitor.
Biol Pharm Bull
; 42(3): 507-511, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30828082
3.
First-dose effect of the SGLT2 inhibitor ipragliflozin on cardiovascular activity in spontaneously diabetic Torii fatty rats.
Clin Exp Pharmacol Physiol
; 46(3): 266-273, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30485488
4.
Protective Effect of Ipragliflozin on Pancreatic Islet Cells in Obese Type 2 Diabetic db/db Mice.
Biol Pharm Bull
; 41(5): 761-769, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29709913
5.
The Sodium Glucose Cotransporter 2 Inhibitor Ipragliflozin Promotes Preferential Loss of Fat Mass in Non-obese Diabetic Goto-Kakizaki Rats.
Biol Pharm Bull
; 40(5): 675-680, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28458353
6.
Antihyperglycemic effect of ipragliflozin, a sodium-glucose co-transporter 2 inhibitor, in combination with oral antidiabetic drugs in mice.
Clin Exp Pharmacol Physiol
; 42(1): 87-93, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25311502
7.
Pharmacokinetics and pharmacodynamics of ASP2151, a helicase-primase inhibitor, in a murine model of herpes simplex virus infection.
Antimicrob Agents Chemother
; 57(3): 1339-46, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23274658
8.
Susceptibility of herpes simplex virus isolated from genital herpes lesions to ASP2151, a novel helicase-primase inhibitor.
Antimicrob Agents Chemother
; 56(7): 3587-91, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22526302
9.
Unique "delta lock" structure of telmisartan is involved in its strongest binding affinity to angiotensin II type 1 receptor.
Biochem Biophys Res Commun
; 404(1): 434-7, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21130741
10.
Preventive and therapeutic effects of tacrolimus in an interleukin-10-deficient mouse model of colitis.
Inflamm Res
; 60(11): 1049-59, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21830095
11.
Tacrolimus ameliorates dextran sulfate sodium-induced colitis in mice: implication of interferon-γ and interleukin-1ß suppression.
Biol Pharm Bull
; 34(12): 1823-7, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22130237
12.
Constitutive increase in active GLP-1 levels by the DPP4 inhibitor ASP4000 on a new meal tolerance test in Zucker fatty rats.
Pharmacol Res
; 60(4): 264-9, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19520592
13.
Effect of ipragliflozin, an SGLT2 inhibitor, on cardiac histopathological changes in a non-diabetic rat model of cardiomyopathy.
Life Sci
; 230: 19-27, 2019 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31125563
14.
ASP4,000, a novel, selective, dipeptidyl peptidase 4 inhibitor with antihyperglycemic activity.
Eur J Pharmacol
; 590(1-3): 444-9, 2008 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18582861
15.
Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats.
Life Sci
; 147: 125-31, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26829386
16.
Functional imaging of pharmacological action of SGLT2 inhibitor ipragliflozin via PET imaging using 11C-MDG.
Pharmacol Res Perspect
; 4(4): e00244, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28116097
17.
A chronic renal rejection model with a fully MHC-mismatched rat strain combination under immunosuppressive therapy.
Transpl Immunol
; 38: 19-26, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27545900
18.
Ameliorating effect of FK614, a novel nonthiazolidinedione peroxisome proliferator-activated receptor gamma agonist, on insulin resistance in Zucker fatty rat.
Eur J Pharmacol
; 519(1-2): 182-90, 2005 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-16039648
19.
FR177391, a new anti-hyperlipidemic agent from Serratia. II. Pharmacological activity of FR177391.
J Antibiot (Tokyo)
; 58(10): 640-7, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16392680
20.
Ipragliflozin, an SGLT2 inhibitor, exhibits a prophylactic effect on hepatic steatosis and fibrosis induced by choline-deficient l-amino acid-defined diet in rats.
Eur J Pharmacol
; 754: 19-24, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25701721