Detalhe da pesquisa
1.
Efficacy, Safety, and Tolerability of Inclisiran in Patients With Homozygous Familial Hypercholesterolemia: Results From the ORION-5 Randomized Clinical Trial.
Circulation
; 149(5): 354-362, 2024 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37850379
2.
Nonsteroidal anti-inflammatory drug-sparing effect of secukinumab in patients with radiographic axial spondyloarthritis: 4-year results from the MEASURE 2, 3 and 4 phase III trials.
Rheumatol Int
; 42(2): 205-213, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34773130
3.
Secukinumab shows sustained efficacy and low structural progression in ankylosing spondylitis: 4-year results from the MEASURE 1 study.
Rheumatology (Oxford)
; 58(5): 859-868, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30590813
4.
Long-term effects of interleukin-17A inhibition with secukinumab in active ankylosing spondylitis: 3-year efficacy and safety results from an extension of the Phase 3 MEASURE 1 trial.
Clin Exp Rheumatol
; 36(1): 50-55, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-28516874
5.
Inclisiran administration potently and durably lowers LDL-C over an extended-term follow-up: the ORION-8 trial.
Cardiovasc Res
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753448
6.
Long-term efficacy and safety of inclisiran in patients with high cardiovascular risk and elevated LDL cholesterol (ORION-3): results from the 4-year open-label extension of the ORION-1 trial.
Lancet Diabetes Endocrinol
; 11(2): 109-119, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36620965
7.
Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy.
J Neurosci
; 31(6): 2125-35, 2011 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21307249
8.
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.
J Clin Invest
; 118(2): 777-88, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18172548
9.
Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.
Hum Mol Genet
; 17(11): 1540-55, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18276609
10.
Methamphetamine inhibits antigen processing, presentation, and phagocytosis.
PLoS Pathog
; 4(2): e28, 2008 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18282092
11.
Secukinumab Demonstrates Sustained Efficacy and Safety in a Taiwanese Subpopulation With Active Ankylosing Spondylitis: Four-Year Results From a Phase 3 Study, MEASURE 1.
Front Immunol
; 11: 561748, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33324394
12.
Long-term efficacy and safety of secukinumab 150 mg in ankylosing spondylitis: 5-year results from the phase III MEASURE 1 extension study.
RMD Open
; 5(2): e001005, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31565244
13.
Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease.
J Neurochem
; 106(1): 24-36, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18384642
14.
Efficacy and Safety of Secukinumab 150 mg with and Without Loading Regimen in Ankylosing Spondylitis: 104-week Results from MEASURE 4 Study.
Rheumatol Ther
; 5(2): 447-462, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30121827
15.
Autophagy protects against Sindbis virus infection of the central nervous system.
Cell Host Microbe
; 7(2): 115-27, 2010 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20159618
16.
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Nat Neurosci
; 13(5): 567-76, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20383138
17.
Adaptive autophagy in Alexander disease-affected astrocytes.
Autophagy
; 4(5): 701-703, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28186854
18.
Adaptive autophagy in Alexander disease-affected astrocytes.
Autophagy
; 4(5): 701-3, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18414043
19.
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein.
Cell Host Microbe
; 1(1): 23-35, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18005679
20.
PKR-dependent autophagic degradation of herpes simplex virus type 1.
Autophagy
; 2(1): 24-9, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16874088