Detalhe da pesquisa
1.
The Discovery of Weddellamycin, a Tricyclic Polyene Macrolactam Antibiotic from an Antarctic Deep-Sea-Derived Streptomyces sp. DSS69, by Heterologous Expression.
Mar Drugs
; 22(4)2024 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38667806
2.
The regulatory gene wblA is a target of the orphan response regulator OrrA in Streptomyces coelicolor.
Environ Microbiol
; 24(7): 3081-3096, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35384219
3.
Unexpected Role of a Short-Chain Dehydrogenase/Reductase Family Protein in Type II Polyketide Biosynthesis.
Angew Chem Int Ed Engl
; 61(7): e202110445, 2022 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34927786
4.
Impact of MtrA on phosphate metabolism genes and the response to altered phosphate conditions in Streptomyces.
Environ Microbiol
; 23(11): 6907-6923, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390613
5.
Enhancing Ristomycin A Production by Overexpression of ParB-Like StrR Family Regulators Controlling the Biosynthesis Genes.
Appl Environ Microbiol
; 87(19): e0106621, 2021 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34505824
6.
RedH and PigC Catalyze the Biosynthesis of Hybrubins via Phosphorylation of 4'-Methoxy-2,2'-Bipyrrole-5'-Carbaldehyde.
Appl Environ Microbiol
; 86(2)2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31704680
7.
A novel XRE family regulator that controls antibiotic production and development in Streptomyces coelicolor.
Appl Microbiol Biotechnol
; 104(23): 10075-10089, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33057789
8.
Functional Genome Mining Reveals a Class V Lanthipeptide Containing a d-Amino Acid Introduced by an F420 H2 -Dependent Reductase.
Angew Chem Int Ed Engl
; 59(41): 18029-18035, 2020 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32648341
9.
Genome-Wide Mutagenesis Links Multiple Metabolic Pathways with Actinorhodin Production in Streptomyces coelicolor.
Appl Environ Microbiol
; 85(7)2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30709825
10.
Novel Two-Component System MacRS Is a Pleiotropic Regulator That Controls Multiple Morphogenic Membrane Protein Genes in Streptomyces coelicolor.
Appl Environ Microbiol
; 85(4)2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530707
11.
Biosynthesis of Tropolones in Streptomyces spp.: Interweaving Biosynthesis and Degradation of Phenylacetic Acid and Hydroxylations on the Tropone Ring.
Appl Environ Microbiol
; 84(12)2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29654178
12.
Reconstitution of Kinamycin Biosynthesis within the Heterologous Host Streptomyces albus J1074.
J Nat Prod
; 81(1): 72-77, 2018 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29338229
13.
Large-Scale Transposition Mutagenesis of Streptomyces coelicolor Identifies Hundreds of Genes Influencing Antibiotic Biosynthesis.
Appl Environ Microbiol
; 83(6)2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062460
14.
Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy.
Metab Eng
; 38: 418-426, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27746324
15.
Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp.
Appl Environ Microbiol
; 82(19): 5795-805, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27451447
16.
BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin.
Biochemistry
; 53(44): 6901-9, 2014 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25299801
17.
Operon for biosynthesis of lipstatin, the Beta-lactone inhibitor of human pancreatic lipase.
Appl Environ Microbiol
; 80(24): 7473-83, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25239907
18.
Identification and characterization of the biosynthetic gene cluster of polyoxypeptin A, a potent apoptosis inducer.
BMC Microbiol
; 14: 30, 2014 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24506891
19.
Bacterial cellulose membranes used as artificial substitutes for dural defection in rabbits.
Int J Mol Sci
; 15(6): 10855-67, 2014 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24937688
20.
Streptomyces-based whole-cell biosensors for detecting diverse cell envelope-targeting antibiotics.
Biosens Bioelectron
; 249: 116004, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38199083