Detalhe da pesquisa
1.
The BET inhibitor GNE-987 effectively induces anti-cancer effects in T-cell acute lymphoblastic leukemia by targeting enhancer regulated genes.
Carcinogenesis
; 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38302114
2.
Super enhancer related gene ANP32B promotes the proliferation of acute myeloid leukemia by enhancing MYC through histone acetylation.
Cancer Cell Int
; 24(1): 81, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383388
3.
The RNA polymerase II subunit B (RPB2) functions as a growth regulator in human glioblastoma.
Biochem Biophys Res Commun
; 674: 170-182, 2023 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37423037
4.
BRD4 inhibitor MZ1 exerts anti-cancer effects by targeting MYCN and MAPK signaling in neuroblastoma.
Biochem Biophys Res Commun
; 604: 63-69, 2022 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35299072
5.
BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes.
Cancer Cell Int
; 21(1): 230, 2021 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33888130
6.
CEBPG promotes acute myeloid leukemia progression by enhancing EIF4EBP1.
Cancer Cell Int
; 21(1): 598, 2021 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34743716
7.
Molecular mechanism of G1 arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells.
Cancer Cell Int
; 17: 35, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28286417
8.
mRNA expression profiling of histone modifying enzymes in pediatric acute monoblastic leukemia.
Pharmazie
; 72(3): 177-186, 2017 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29442054
9.
Analyzing the gene expression profile of anaplastic histology Wilms' tumor with real-time polymerase chain reaction arrays.
Cancer Cell Int
; 15: 44, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26136641
10.
Hypermethylation of the GATA binding protein 4 (GATA4) promoter in Chinese pediatric acute myeloid leukemia.
BMC Cancer
; 15: 756, 2015 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26490736
11.
Molecular targeting of the oncoprotein PLK1 in pediatric acute myeloid leukemia: RO3280, a novel PLK1 inhibitor, induces apoptosis in leukemia cells.
Int J Mol Sci
; 16(1): 1266-92, 2015 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25574601
12.
Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation.
J Transl Med
; 12: 182, 2014 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24962166
13.
METTL14 promotes neuroblastoma formation by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanism.
Cell Death Discov
; 10(1): 186, 2024 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38649363
14.
CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma.
Cancer Lett
; 591: 216882, 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38636893
15.
Differential mRNA expression levels of human histone-modifying enzymes in normal karyotype B cell pediatric acute lymphoblastic leukemia.
Int J Mol Sci
; 14(2): 3376-94, 2013 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23389039
16.
Super Enhancer Regulatory Gene FYB1 Promotes the Progression of T Cell Acute Lymphoblastic Leukemia by Activating IGLL1.
J Immunol Res
; 2023: 3804605, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37767202
17.
BRD4 PROTAC degrader MZ1 exhibits anti-B-cell acute lymphoblastic leukemia effects via targeting CCND3.
Hematology
; 28(1): 2247253, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37594294
18.
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1.
Cell Death Dis
; 14(8): 518, 2023 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37573405
19.
Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells.
BMC Cancer
; 12: 619, 2012 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23267699
20.
BRD4 Inhibitor GNE-987 Exerts Anticancer Effects by Targeting Super-Enhancer-Related Gene LYL1 in Acute Myeloid Leukemia.
J Immunol Res
; 2022: 7912484, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35958877