Detalhe da pesquisa
1.
Neuroprotection by Drugs, Nutraceuticals and Physical Activity.
Int J Mol Sci
; 24(4)2023 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36834601
2.
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer's disease.
Bioorg Med Chem
; 71: 116952, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35930852
3.
Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases.
Neurochem Res
; 45(12): 3003-3020, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33079324
4.
Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3ß Inhibitors with Improved Metabolic Stability.
Int J Mol Sci
; 21(21)2020 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33105671
5.
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease.
Molecules
; 25(14)2020 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32664425
6.
Curcumin and Heme Oxygenase: Neuroprotection and Beyond.
Int J Mol Sci
; 20(10)2019 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31100781
7.
Protective Effects of 6-(Methylsulfinyl)hexyl Isothiocyanate on Aß1-42-Induced Cognitive Deficit, Oxidative Stress, Inflammation, and Apoptosis in Mice.
Int J Mol Sci
; 19(7)2018 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30021941
8.
Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer's Disease.
Molecules
; 23(8)2018 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061534
9.
The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones.
Molecules
; 23(7)2018 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30037040
10.
Isothiocyanates Are Promising Compounds against Oxidative Stress, Neuroinflammation and Cell Death that May Benefit Neurodegeneration in Parkinson's Disease.
Int J Mol Sci
; 17(9)2016 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27598127
11.
Naturally Inspired Molecules as Multifunctional Agents for Alzheimer's Disease Treatment.
Molecules
; 21(5)2016 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27196880
12.
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold.
Bioorg Med Chem Lett
; 25(14): 2804-8, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26003339
13.
Antioxidant and Anti-Melanogenesis Effects of Teucrium chamaedrys L. Cell Suspension Extract and Its Main Phenylethanoid Glycoside in B16-F10 Cells.
Plants (Basel)
; 13(6)2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38592786
14.
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3ß/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer's Disease.
ACS Chem Neurosci
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38747979
15.
Chrysin bonded to ß-d-glucose tetraacetate enhances its protective effects against the neurotoxicity induced by aluminum in Swiss mice.
J Pharm Pharmacol
; 76(4): 368-380, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38330395
16.
A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models.
Chem Biol Interact
; 395: 111026, 2024 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38679115
17.
PROTAC-Induced Glycogen Synthase Kinase 3ß Degradation as a Potential Therapeutic Strategy for Alzheimer's Disease.
ACS Chem Neurosci
; 14(11): 1963-1970, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37218653
18.
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.
Eur J Med Chem
; 252: 115297, 2023 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36996713
19.
Neuroprotective effects of erucin against 6-hydroxydopamine-induced oxidative damage in a dopaminergic-like neuroblastoma cell line.
Int J Mol Sci
; 13(9): 10899-10910, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23109827
20.
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3ß Inhibitors.
J Med Chem
; 65(2): 1283-1301, 2022 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34213342