Detalhe da pesquisa
1.
Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer.
Immunity
; 55(4): 701-717.e7, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35364006
2.
Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells.
Nature
; 611(7936): 603-613, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36352230
3.
Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance.
Immunity
; 49(6): 1132-1147.e7, 2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30552022
4.
cDC2 plasticity and acquisition of a DC3-like phenotype mediated by IL-6 and PGE2 in a patient-derived colorectal cancer organoids model.
Eur J Immunol
; 54(6): e2350891, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509863
5.
IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction.
J Hepatol
; 80(4): 634-644, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38160941
6.
TGFß drives immune evasion in genetically reconstituted colon cancer metastasis.
Nature
; 554(7693): 538-543, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29443964
7.
Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation.
J Proteome Res
; 22(1): 138-151, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36450103
8.
Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.
Nature
; 530(7590): 340-3, 2016 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26863187
9.
TMEM59 potentiates Wnt signaling by promoting signalosome formation.
Proc Natl Acad Sci U S A
; 115(17): E3996-E4005, 2018 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29632210
10.
Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl.
Mol Cell
; 37(5): 607-19, 2010 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20227366
11.
Wnt/ß-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled.
Proc Natl Acad Sci U S A
; 109(14): E812-20, 2012 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22411803
12.
Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts.
J Cell Sci
; 125(Pt 14): 3430-42, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22467858
13.
Exploring immune status in peripheral blood and tumor tissue in association with survival in patients with multi-organ metastatic colorectal cancer.
Oncoimmunology
; 13(1): 2361971, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38868078
14.
Targeting CAFs to Improve Anti-PD-1 Checkpoint Immunotherapy.
Cancer Res
; 83(5): 655-656, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36861359
15.
Dendritic cell phenotype and function in a 3D co-culture model of patient-derived metastatic colorectal cancer organoids.
Front Immunol
; 14: 1105244, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36761758
16.
Overcoming TGFß-mediated immune evasion in cancer.
Nat Rev Cancer
; 22(1): 25-44, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34671117
17.
Lost in translation: Revisiting the use of tyrosine kinase inhibitors in colorectal cancer.
Cancer Treat Rev
; 110: 102466, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36183569
18.
Mutant RAS and the tumor microenvironment as dual therapeutic targets for advanced colorectal cancer.
Cancer Treat Rev
; 109: 102433, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35905558
19.
High-Dose Intermittent Treatment with the Multikinase Inhibitor Sunitinib Leads to High Intra-Tumor Drug Exposure in Patients with Advanced Solid Tumors.
Cancers (Basel)
; 14(24)2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36551546
20.
Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy.
Nat Cancer
; 3(9): 1052-1070, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35773527