Detalhe da pesquisa
1.
Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humans.
J Pharmacol Exp Ther
; 346(2): 219-28, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23709115
2.
Amide-based inhibitors of p38alpha MAP kinase. Part 1: discovery of novel N-pyridyl amide lead molecules.
Bioorg Med Chem Lett
; 20(8): 2556-9, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20346653
3.
Amide-based inhibitors of p38alpha MAP kinase. Part 2: design, synthesis and SAR of potent N-pyrimidyl amides.
Bioorg Med Chem Lett
; 20(8): 2560-3, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20346659
4.
Design and synthesis of piperazine-indole p38 alpha MAP kinase inhibitors with improved pharmacokinetic profiles.
Bioorg Med Chem Lett
; 20(3): 828-31, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20071169
5.
In vitro and in vivo characterization of irreversible mutant-selective EGFR inhibitors that are wild-type sparing.
Mol Cancer Ther
; 13(6): 1468-79, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24723450