Detalhe da pesquisa
1.
Lack of CYP3A4 protein induction despite mRNA induction in primary hepatocytes exposed to rifabutin as a possible explanation for its low interaction risk in vivo.
Arch Toxicol
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38713375
2.
Rifabutin but not rifampicin can partly out-balance P-glycoprotein induction by concurrent P-glycoprotein inhibition through high affinity binding to the inhibitory site.
Arch Toxicol
; 98(1): 223-231, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37833491
3.
Molecular prediction of clinical response to anti-PD-1/anti-PD-L1 immune checkpoint inhibitors: New perspectives for precision medicine and mass spectrometry-based investigations.
Int J Cancer
; 153(2): 252-264, 2023 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36408912
4.
Comprehensive in vitro analysis evaluating the variable drug-drug interaction risk of rifampicin compared to rifabutin.
Arch Toxicol
; 97(8): 2219-2230, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37285043
5.
How to avoid misinterpretation of dual reporter gene assay data affected by cell damage.
Arch Toxicol
; 96(9): 2501-2510, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35678845
6.
A nuclear factor kappa B reporter cell line used to evaluate ex vivo the net inflammatory effect of plasma samples from patients with rheumatoid arthritis, psoriasis, or COVID-19.
Cytokine
; 138: 155399, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33338916
7.
Approaching sites of action of drugs in clinical pharmacology: New analytical options and their challenges.
Br J Clin Pharmacol
; 87(3): 858-874, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32881012
8.
Reporter cell assay-based functional quantification of TNF-α-antagonists in serum - a proof-of-principle study for adalimumab.
Anal Biochem
; 596: 113646, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32112722
9.
Methadone against cancer: Lost in translation.
Int J Cancer
; 143(8): 1840-1848, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29516505
10.
Physiology-based pharmacokinetic modelling and experimental data suggest that rifabutin alters dolutegravir kinetics by both P-glycoprotein induction and concurrent inhibition.
Br J Clin Pharmacol
; 89(7): 2329-2331, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37077127
11.
Impact of enzalutamide and its main metabolite N-desmethyl enzalutamide on pharmacokinetically important drug metabolizing enzymes and drug transporters.
Biopharm Drug Dispos
; 38(9): 517-525, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28865089
12.
Under-Reported Aspects of Platinum Drug Pharmacology.
Molecules
; 22(3)2017 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29760371
13.
Bortezomib and ixazomib protect firefly luciferase from degradation and can flaw respective reporter gene assays.
Anal Biochem
; 509: 124-129, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27325500
14.
Fetal calf sera can distort cell-based luminescent proteasome assays through heat-resistant chymotrypsin-like activity.
Anal Biochem
; 471: 23-5, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25447494
15.
Desmethyl bosentan displays a similar in vitro interaction profile as bosentan.
Pulm Pharmacol Ther
; 30: 80-6, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25535031
16.
Bosentan enhances in vitro bortezomib's anti-proliferative potency against multiple myeloma by mechanisms going beyond endothelin receptor blockade.
Br J Haematol
; 184(6): 1052-1055, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29676451
17.
Given the Data of Hommers and Colleagues, Valproic Acid Is Not an Unequivocal Inducer of Clozapine Metabolism.
J Clin Psychopharmacol
; 39(4): 419-420, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31188239
18.
RNA is a pro-apoptotic target of cisplatin in cancer cell lines and C. elegans.
Biomed Pharmacother
; 173: 116450, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38503239
19.
The differences in drug disposition gene induction by rifampicin and rifabutin are unlikely due to different effects on important pregnane X receptor (NR1I2) splice variants.
Naunyn Schmiedebergs Arch Pharmacol
; 397(4): 2485-2496, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37851058
20.
Watch out for reporter gene assays with Renilla luciferase and paclitaxel.
Anal Biochem
; 437(2): 109-10, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23499973