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J Glob Antimicrob Resist ; 10: 1-2, 2017 09.
Artigo em Inglês | MEDLINE | ID: mdl-28576740

RESUMO

The genus Kluyvera comprises potential pathogens that can cause many infections. This study reports a Kluyvera intermedia strain (FOSA7093) from a pancreatic cyst specimen from a long-term hospitalised patient. Whole-genome sequencing (WGS) of the K. intermedia isolate was performed and the strain was reported as sensitive to Danish-registered antibiotics although it had a fosA-like gene in the genome. There were nine contigs that aligned to a plasmid, and these contigs contained several heavy metal resistance gene homologues. Furthermore, a prophage was discovered in the genome. WGS represents an efficient tool for monitoring Kluyvera spp. and its role as a reservoir of multidrug resistance. Therefore, this susceptible K. intermedia genome has many characteristics that allow comparison of resistant K. intermedia that might be discovered in the future.


Assuntos
Abscesso/microbiologia , Infecções por Enterobacteriaceae/microbiologia , Kluyvera/genética , Kluyvera/isolamento & purificação , Kluyvera/patogenicidade , Antibacterianos , Proteínas de Bactérias/genética , DNA Bacteriano , Farmacorresistência Bacteriana Múltipla/genética , Humanos , Kluyvera/efeitos dos fármacos , Testes de Sensibilidade Microbiana , Plasmídeos , Sequenciamento Completo do Genoma , beta-Lactamases/genética
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