Detalhe da pesquisa
1.
Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes.
Cell
; 157(6): 1309-1323, 2014 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24906149
2.
Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes.
Cell
; 161(5): 1229, 2015 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28910642
3.
Hypoxia as a potential inducer of immune tolerance, tumor plasticity and a driver of tumor mutational burden: Impact on cancer immunotherapy.
Semin Cancer Biol
; 97: 104-123, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38029865
4.
Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells.
Nat Immunol
; 12(8): 770-7, 2011 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21685908
5.
Role of Hypoxic Stress in Regulating Tumor Immunogenicity, Resistance and Plasticity.
Int J Mol Sci
; 19(10)2018 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30301213
6.
Granzyme B-activated p53 interacts with Bcl-2 to promote cytotoxic lymphocyte-mediated apoptosis.
J Immunol
; 194(1): 418-28, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25404359
7.
Mechanisms of Cytotoxic Lymphocyte-Mediated Apoptosis and Relationship with the Tumor Suppressor p53.
Crit Rev Immunol
; 35(6): 433-49, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-27279042
8.
Perforin: a key pore-forming protein for immune control of viruses and cancer.
Subcell Biochem
; 80: 197-220, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24798013
9.
Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling.
PLoS Genet
; 7(11): e1002363, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22102825
10.
Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis.
Blood
; 115(8): 1582-93, 2010 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20038786
11.
Modulation of the antitumor immune response by cancer-associated fibroblasts: mechanisms and targeting strategies to hamper their immunosuppressive functions.
Explor Target Antitumor Ther
; 3(5): 598-629, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36338519
12.
The Effect of Hypoxia and Hypoxia-Associated Pathways in the Regulation of Antitumor Response: Friends or Foes?
Front Immunol
; 13: 828875, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35211123
13.
p53 reactivating small molecule PRIMA1MET/APR246 regulates genomic instability in MDAMB231 cells.
Oncol Rep
; 47(4)2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35234267
14.
Hypoxia increases melanoma-associated fibroblasts immunosuppressive potential and inhibitory effect on T cell-mediated cytotoxicity.
Oncoimmunology
; 10(1): 1950953, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34367731
15.
Selection of tumorresistant variants following sustained natural killer cellmediated immune stress.
Oncol Rep
; 45(2): 582-594, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33416152
16.
The Most Common VHL Point Mutation R167Q in Hereditary VHL Disease Interferes with Cell Plasticity Regulation.
Cancers (Basel)
; 13(15)2021 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34359798
17.
Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival.
Cancers (Basel)
; 13(3)2021 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33573362
18.
Hypoxia increases mutational load of breast cancer cells through frameshift mutations.
Oncoimmunology
; 9(1): 1750750, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32363122
19.
Tumor resistance to specific lysis: a major hurdle for successful immunotherapy of cancer.
Clin Immunol
; 130(1): 34-40, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19013109
20.
The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy.
Cell Death Dis
; 10(10): 695, 2019 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31541080