Detalhe da pesquisa
1.
Implementation of in vitro glycoengineering of monoclonal antibodies into downstream processing of industrial production.
Glycobiology
; 32(2): 123-135, 2022 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34939096
2.
Oxidation of M252 but not M428 in hu-IgG1 is responsible for decreased binding to and activation of hu-FcγRIIa (His131).
Biologicals
; 50: 125-128, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28988621
3.
Two N-terminally truncated variants of human ß-galactoside α2,6 sialyltransferase I with distinct properties for in vitro protein glycosylation.
Glycobiology
; 26(10): 1097-1106, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27102286
4.
High-quality production of human α-2,6-sialyltransferase in Pichia pastoris requires control over N-terminal truncations by host-inherent protease activities.
Microb Cell Fact
; 13(1): 138, 2014 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25365915
5.
Assessing production variability in empty and filled adeno-associated viruses by single molecule mass analyses.
Mol Ther Methods Clin Dev
; 27: 491-501, 2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36458114
6.
Clearance of therapeutic antibody glycoforms after subcutaneous and intravenous injection in a porcine model.
MAbs
; 14(1): 2145929, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36383465
7.
Glycoform-resolved pharmacokinetic studies in a rat model employing glycoengineered variants of a therapeutic monoclonal antibody.
MAbs
; 13(1): 1865596, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33382957
8.
Interaction analysis of glycoengineered antibodies with CD16a: a native mass spectrometry approach.
MAbs
; 12(1): 1736975, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32167012
9.
The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange.
Antibodies (Basel)
; 8(4)2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31581521
10.
Effects of sialic acid linkage on antibody-fragment crystallizable receptor binding and antibody dependent cytotoxicity depend on levels of fucosylation/bisecting.
Bioanalysis
; 11(15): 1437-1449, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31490109
11.
Fc-galactosylation modulates antibody-dependent cellular cytotoxicity of therapeutic antibodies.
Mol Immunol
; 73: 69-75, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27058641
12.
In vitro glycoengineering of IgG1 and its effect on Fc receptor binding and ADCC activity.
PLoS One
; 10(8): e0134949, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26266936
13.
Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants.
PLoS One
; 10(12): e0143520, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26657484