Detalhe da pesquisa
1.
Cardiac Sarcomere Signaling in Health and Disease.
Int J Mol Sci
; 23(24)2022 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36555864
2.
Advancing physiological maturation in human induced pluripotent stem cell-derived cardiac muscle by gene editing an inducible adult troponin isoform switch.
Stem Cells
; 38(10): 1254-1266, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32497296
3.
Sarcomere integrated biosensor detects myofilament-activating ligands in real time during twitch contractions in live cardiac muscle.
J Mol Cell Cardiol
; 147: 49-61, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32791214
4.
Chemoproteomic Identification of Serine Hydrolase RBBP9 as a Valacyclovir-Activating Enzyme.
Mol Pharm
; 17(5): 1706-1714, 2020 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32196348
5.
Cytoplasmic nucleic acid-based XNAs directly enhance live cardiac cell function by a Ca2+ cycling-independent mechanism via the sarcomere.
J Mol Cell Cardiol
; 130: 1-9, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30849419
6.
TnI Structural Interface with the N-Terminal Lobe of TnC as a Determinant of Cardiac Contractility.
Biophys J
; 114(7): 1646-1656, 2018 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29642034
7.
Sarcomere neutralization in inherited cardiomyopathy: small-molecule proof-of-concept to correct hyper-Ca2+-sensitive myofilaments.
Am J Physiol Heart Circ Physiol
; 311(1): H36-43, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27199134
8.
Molecular determinants of cardiac myocyte performance as conferred by isoform-specific TnI residues.
Biophys J
; 106(10): 2105-14, 2014 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24853739
9.
Myofilament-based physiological regulatory compensation preserves diastolic function in failing hearts with severe Ca2+ handling deficits.
JCI Insight
; 9(6)2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38329806
10.
Inducing positive inotropy in human iPSC-derived cardiac muscle by gene editing-based activation of the cardiac α-myosin heavy chain.
Sci Rep
; 14(1): 3915, 2024 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38365813
11.
Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers.
Skelet Muscle
; 13(1): 9, 2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37208786
12.
Physiologically-Based Pharmacokinetic Modeling to Predict Methylphenidate Exposure Affected by Interplay Among Carboxylesterase 1 Pharmacogenetics, Drug-Drug Interactions, and Sex.
J Pharm Sci
; 111(9): 2606-2613, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526575
13.
Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers.
Sci Rep
; 12(1): 18116, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302792
14.
Oxidative stress pathogenically remodels the cardiac myocyte cytoskeleton via structural alterations to the microtubule lattice.
Dev Cell
; 56(15): 2252-2266.e6, 2021 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34343476
15.
Pharmacokinetics of gemcitabine and its amino acid ester prodrug following intravenous and oral administrations in mice.
Biochem Pharmacol
; 180: 114127, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32603666
16.
Mechanisms of gemcitabine oral absorption as determined by in situ intestinal perfusions in mice.
Biochem Pharmacol
; 168: 57-64, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31207211
17.
Gene Transfer of Calcium-Binding Proteins into Adult Cardiac Myocytes.
Methods Mol Biol
; 1929: 187-205, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30710274
18.
Functional Equivalence of Retroviral MA Domains in Facilitating Psi RNA Binding Specificity by Gag.
Viruses
; 8(9)2016 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27657107
19.
Cell biology of sarcomeric protein engineering: disease modeling and therapeutic potential.
Anat Rec (Hoboken)
; 297(9): 1663-9, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25125179
20.
Fatty acid flux in adipocytes: the in's and out's of fat cell lipid trafficking.
Mol Cell Endocrinol
; 318(1-2): 24-33, 2010 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19720110