Detalhe da pesquisa
1.
The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female mice.
Diabetologia
; 65(3): 490-505, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34932133
2.
Polyglutamine-Related Aggregates Can Serve as a Potent Antigen Source for Cross-Presentation by Dendritic Cells.
J Immunol
; 205(10): 2583-2594, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33067378
3.
Endoplasmic Reticulum Homeostasis Regulates TLR4 Expression and Signaling in Mast Cells.
Int J Mol Sci
; 23(19)2022 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36233127
4.
Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation.
Mol Cell Proteomics
; 18(7): 1330-1344, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31010818
5.
Opposing effects of intracellular versus extracellular adenine nucleotides on autophagy: implications for ß-cell function.
J Cell Sci
; 131(15)2018 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30002135
6.
Aripiprazole Cytotoxicity Coincides with Activation of the Unfolded Protein Response in Human Hepatic Cells.
J Pharmacol Exp Ther
; 374(3): 452-461, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32554435
7.
Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1.
FASEB J
; 33(3): 3481-3495, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30452881
8.
The direction of protein entry into the proteasome determines the variety of products and depends on the force needed to unfold its two termini.
Mol Cell
; 48(4): 601-11, 2012 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23041283
9.
Towards Enhancing Therapeutic Glycoprotein Bioproduction: Interventions in the PI3K/AKT/mTOR Pathway.
Cell Struct Funct
; 44(2): 75-83, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31353334
10.
Low concentrations of cadmium chloride promotes protein translation and improve cell line productivity.
Biotechnol Bioeng
; 116(3): 569-580, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30512193
11.
mTORC1 activation in B cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity.
Immunology
; 155(4): 505-518, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30144045
12.
Engineering CHO cells with an oncogenic KIT improves cells growth, resilience to stress, and productivity.
Biotechnol Bioeng
; 114(11): 2560-2570, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28627778
13.
Metabolic Control of Plasma Cell Differentiation- What We Know and What We Don't Know.
J Clin Immunol
; 36 Suppl 1: 12-7, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26910101
14.
CHO cells knocked out for TSC2 display an improved productivity of antibodies under fed batch conditions.
Biotechnol Bioeng
; 113(9): 1942-52, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26888596
15.
Regulated IRE1-dependent decay participates in curtailing immunoglobulin secretion from plasma cells.
Eur J Immunol
; 44(3): 867-76, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24242955
16.
Cytomegalovirus downregulates IRE1 to repress the unfolded protein response.
PLoS Pathog
; 9(8): e1003544, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23950715
17.
Placing a disrupted degradation motif at the C terminus of proteasome substrates attenuates degradation without impairing ubiquitylation.
J Biol Chem
; 288(18): 12645-53, 2013 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23519465
18.
Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization.
J Biol Chem
; 288(43): 30904-16, 2013 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24019516
19.
DR5 disulfide bonding as a sensor and effector of protein folding stress.
bioRxiv
; 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38496520
20.
IRE1 endoribonuclease signaling promotes myeloid cell infiltration in glioblastoma.
Neuro Oncol
; 26(5): 858-871, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38153426