Detalhe da pesquisa
1.
Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment.
Antimicrob Agents Chemother
; 62(8)2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866875
2.
Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties.
Bioorg Med Chem Lett
; 27(8): 1840-1847, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28274633
3.
Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug.
Antimicrob Agents Chemother
; 58(4): 1930-42, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24419349
4.
Novel, sulfonamide linked inhibitors of the hepatitis C virus NS3 protease.
Bioorg Med Chem Lett
; 24(3): 969-72, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24405705
5.
Novel mutations in a tissue culture-adapted hepatitis C virus strain improve infectious-virus stability and markedly enhance infection kinetics.
J Virol
; 85(8): 3978-85, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21289124
6.
Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors.
Bioorg Med Chem Lett
; 22(13): 4288-92, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22664130
7.
A biodegradable, acellular xenogeneic scaffold for regeneration of the vocal fold lamina propria.
Tissue Eng
; 13(3): 551-66, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17518602
8.
Elasticity of the human false vocal fold.
Ann Otol Rhinol Laryngol
; 115(5): 370-81, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16739670
9.
Structural and regulatory elements of HCV NS5B polymerase--ß-loop and C-terminal tail--are required for activity of allosteric thumb site II inhibitors.
PLoS One
; 9(1): e84808, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24416288
10.
Highly potent HCV NS4B inhibitors with activity against multiple genotypes.
J Med Chem
; 57(5): 2161-6, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24512292
11.
Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors.
ACS Med Chem Lett
; 2(10): 715-9, 2011 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900257
12.
Relative contributions of collagen and elastin to elasticity of the vocal fold under tension.
Ann Biomed Eng
; 35(8): 1471-83, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17453348