Detalhe da pesquisa
1.
Wnt/ß-catenin and NFκB signaling synergize to trigger growth factor-free regeneration of adult primary human hepatocytes.
Hepatology
; 2023 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37870288
2.
Discovery of 3-Amino-1H-pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family.
Int J Mol Sci
; 23(23)2022 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499165
3.
Image-Based Annotation of Chemogenomic Libraries for Phenotypic Screening.
Molecules
; 27(4)2022 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35209227
4.
Annotation of the Effect of Chemogenomic Compounds on Cell Health Using High-Content Microscopy in Live-Cell Mode.
Methods Mol Biol
; 2706: 59-73, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558941
5.
Characterization of Cellular Viability Using Label-Free Brightfield Live-Cell Imaging.
Methods Mol Biol
; 2706: 75-88, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558942
6.
A machine learning and live-cell imaging tool kit uncovers small molecules induced phospholipidosis.
Cell Chem Biol
; 30(12): 1634-1651.e6, 2023 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37797617
7.
Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum.
ACS Chem Biol
; 18(4): 822-836, 2023 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36944371
8.
Shifting the selectivity of pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily.
Eur J Med Chem
; 254: 115347, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37094449
9.
High-content live-cell multiplex screen for chemogenomic compound annotation based on nuclear morphology.
STAR Protoc
; 3(4): 101791, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36317177
10.
Compilation and evaluation of a fatty acid mimetics screening library.
Biochem Pharmacol
; 204: 115191, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35907497
11.
Illuminating the Dark: Highly Selective Inhibition of Serine/Threonine Kinase 17A with Pyrazolo[1,5-a]pyrimidine-Based Macrocycles.
J Med Chem
; 65(11): 7799-7817, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35608370
12.
Development of a potent and selective chemical probe for the pleiotropic kinase CK2.
Cell Chem Biol
; 28(4): 546-558.e10, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33484635
13.
Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe.
J Med Chem
; 64(18): 13451-13474, 2021 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34506142
14.
Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor.
Eur J Med Chem
; 208: 112770, 2020 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32883634
15.
A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice.
Commun Chem
; 3(1): 174, 2020 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36703463