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1.
Pan Afr Med J ; 47: 88, 2024.
Artigo em Francês | MEDLINE | ID: mdl-38737225

RESUMO

Ectopic ACTH-secreting pheochromocytoma is a very rare cause of Cushing´s syndrome, posing diagnostic and therapeutic challenges. We here report the case of a female patient with suspected severe Cushing´s syndrome associated with melanoderma, arterial hypertension resistant to triple therapy and unbalanced diabetes treated with insulin therapy. Biologically, urinary ethoxylated, 24-hour urinary free cortisol and ACTH were very high. Imaging showed a 3.5 cm left adrenal mass. The patient underwent left adrenalectomy after medical preparation, with good clinico-biological outcome. Anatomopathological examination confirmed the diagnosis of pheochromocytoma. This case study highlights the importance of measuring methoxylated derivatives in any patient with ACTH-dependent Cushing´s syndrome associated with an adrenal mass. The aim is to ensure early treatment and avoid life-threatening complications.


Assuntos
Neoplasias das Glândulas Suprarrenais , Hormônio Adrenocorticotrópico , Feocromocitoma , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias das Glândulas Suprarrenais/diagnóstico , Neoplasias das Glândulas Suprarrenais/metabolismo , Neoplasias das Glândulas Suprarrenais/complicações , Adrenalectomia/métodos , Hormônio Adrenocorticotrópico/metabolismo , Síndrome de Cushing/etiologia , Síndrome de Cushing/diagnóstico , Hidrocortisona/metabolismo , Hipertensão/etiologia , Feocromocitoma/diagnóstico , Feocromocitoma/metabolismo , Feocromocitoma/complicações
2.
Pan Afr Med J ; 44: 186, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37484588

RESUMO

Carpal tunnel syndrome (CTS) is the most common neuropathy in acromegalic patients and is often the initial complaint. However, the diagnosis of acromegaly is often made years after the diagnosis of CTS. In our case report, we describe the case of a patient in whom acromegaly was discovered after presenting bilateral carpal tunnel syndrome, without having acrofacial signs. Increased awareness of signs of acromegaly in patients with CTS might help to shorten the diagnostic delay in acromegaly.


Assuntos
Acromegalia , Síndrome do Túnel Carpal , Humanos , Síndrome do Túnel Carpal/etiologia , Acromegalia/diagnóstico , Diagnóstico Tardio/efeitos adversos
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